Botulinum Toxin: Uses, Mechanisms of Action and Complications


Fausto E. Marino (Editor)
Sebastiano De Luca (Editor)

Series: Bacteriology Research Developments, Neuroscience Research Progress
BISAC: SCI006000

Botulinum toxin (BoNT) is a powerful neurotoxin produced by the bacterium Clostridium botulinum. Its mechanism of action consists of the induction of a temporary muscle paralysis through the inhibition of the release of acetylcholine into the synaptic cleft. In this book, the authors discuss the uses and complications of botulinum toxin. Topics include the potential therapeutic applications of botulinum toxin in pain management and human epilepsy; a review of the efficacy and safety of currently available products; lower facial contouring with botulinum toxin; BoNT in urology, facial palsy, treatment of body deformities due to muscle hypertrophy, and for drug-refractory trigeminal neuralgia. (Imprint: Nova Biomedical )


Table of Contents

Table of Contents


Botox: Mechanism Of Action, Uses And Side Effects
(Penny Robshaw MRCOG, Urogynaecology Department, St Mary’s Hospital, London W2, and others)

Effects of Botulinum Toxin on Neuronal Communication: Converging Evidences of Central Effects
(C. Rasetti-Escargueil, National Institute for Biological Standards and Control, A Centre of Health Protection Agency, South Mimms, Potters Bar, United Kingdom)

Aesthetic Indications of Botulinum Toxin: A Review of the Efficacy and Safety of Currently Available Products
(Luca A. Dessy, Nefer Fallico, Marco Mazzocchi, Nicolò Scuderi, Department of Plastic and Reconstructive Surgery, ‘‘Sapienza’’ University of Rome, Rome, Italy, and others)

The Use of Botulinum Toxin in the Treatment of Pain
(Dominique Batifol, Pierre-Jacques Finiels, Unité de Neurochirurgie et de Pathologie Rachidienne, Polyclinique Chirurgicale, Kennedy, Nîmes, France)

Lower Facial Contouring with Botulinum Toxin: Functional and Aesthetic Aspects
(Raffaele Rauso, Roberto Amore, Consultant Aesthetic-Plastic Surgery, Consultant Cranio-Facial Surgery, Centro Polispecialistico Santa Apollonia, S.M.C.V. (CE), Italy, and others)

Botulinum Toxin in Urology: Uses, Mechanisms of Action, Results and Complications
(Cristobal Marchal, Felipe Saez-Barranquero, Maximino Redondo, Urology Department, Virgen de la Victoria Hospital, Málaga, Spain, and others)

Botulinum Toxin and Facial Palsy
(M.L. Navarrete, L. Torrent, J. Junyent, J.F. Fuentes, J.R. Moya, A.L. Arellano, Otorhinolaryngology and Rehabilitation Departments, Vall d´Hebron Hospital, Autònoma University of Barcelona, Spain, and others)

Treatment of Body Deformities Due to Muscle Hypertrophy with Botulinum Toxin A
(Luca A. Dessy, Marco Mazzocchi, Nefer Fallico, Nicolò Scuderi, Department of Plastic and Reconstructive Surgery, ‘‘Sapienza’’ University of Rome, Rome, Italy, and others)

Effectiveness of Botulinum Toxin Type A Injection for TMJ Pain and Clicking
(Ali Hassani, Mohammad Hosein Kalantar Motamedi, Sarang Saadat, Mohammad Hamed Mansouri, Oral and Maxillofacial Surgery, Azad University of Medical Sciences, Tehran, Iran, and others)

Botulinum Toxin A for Drug-Refractory Trigeminal Neuralgia
(Behnam Bohluli, Mohammad Hosein Kalantar Motamedi, Azad University, Dept. of OMF Surgery, Dental Branch, Tehran, Iran, and others)



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