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Quick ViewThis practical guide to the management of thyroid nodules and cancer offers the practitioner a common-sense approach to the management of an increasingly common clinical problem. Thyroid cancer is the most rapidly increasing cancer diagnosis in the United States and is now the fifth most common cancer among women. Indeed, an estimated 65,000 adults (15,000…
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Quick ViewThe prevalence of gestational diabetes mellitus (GDM) is increasing among women worldwide. Gestational diabetes mellitus is defined as abnormal glucose metabolism that initially occurs, or is first recognized, during pregnancy. Early diagnosis of GDM minimizes the exposure of the developing fetus to suboptimal conditions and prevents perinatal complications. This book discusses the risk factors GDM…
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Quick ViewMetabolic syndrome is a clustering of cardio-metabolic risk factors that include obesity, insulin resistance, hypertension and dyslipidemia. These risk factors also contribute to cellular dysfunction and redox imbalance that enhance the progression of a pro-oxidative environment leading to damaged biomolecules, which are highly reactive in nature and can promote cell and tissue dysfunction leading to…
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Quick ViewEndocrinology and metabolic diseases involve very common diseases like diabetes, obesity, polycystic ovary syndrome, hypertension and thyroid disorders. Endocrinology diseases especially adrenal, pituitary, thyroid, gonadal, and metabolic-related diseases require clinical experience, expertise and collaboration with other departments, and are so important for evaluating endocrine diseases. Expertise can only be gained by different case evaluations. Endocrinologists…
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Quick ViewThis practical guide to the management of thyroid nodules and cancer offers the practitioner a common-sense approach to the management of an increasingly common clinical problem. Thyroid cancer is the most rapidly increasing cancer diagnosis in the United States and is now the fifth most common cancer among women. Indeed, an estimated 65,000 adults (15,000…
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Quick ViewThis book presents an overview of the research advances and clinical challenges of the pineal gland. The topics analyzed cover a broad spectrum of functions played by the pineal gland and present new information in this area of research. These topics include: the physiology and pathology of skeletal and cardiac muscles; the beneficial actions of…
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Quick ViewCystic tumors of the pancreas today are diagnosed more frequently in clinical practice, mainly due to an increased use of the modern advanced imaging modalities. Bland cysts of the pancreas most often develop after chronic or acute inflammation of the pancreas. However, the current knowledge concerning the development of cystic neoplasias of the pancreas is…
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Quick ViewSomatic growth is a crucial component in the development of an organism. Growth is manifested in many levels during an organism’s lifespan; rapid intrauterine growth is followed by extrauterine development that subsides with age. The control of growth is exerted via particularly complex and multifaceted mechanisms that affect every cell of the body, regulating the…
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Quick ViewThis book focuses on the regulation, function and further research insights on aldosterone. Chapter One discusses the role of aldosterone in the causation of cardiac oedema and highlights areas for potential future research. Chapter Two reviews secondary arterial hypertension due to primary hyperaldosteronism. Chapter Three summarizes the present knowledge about the role of aldosterone in…
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Quick ViewThe Art of Neuroendocrinology: A Case-based Approach to Medical Decision-Making is not your standard textbook of pituitary endocrinology. This comprehensive collection of works presents unique, interesting, and often challenging patient cases. These reports illustrate the complexities of medical decision-making, incorporating evidence-based medicine and the practice of the art of medicine, in the evaluation and management…
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Quick ViewIn Chapter One, Dr. Med. Ioannis Iakovou examines whether the link between weight and bone mineral density is caused by or directly correlated with leptin and adiponectin. Afterwards, Chapter Two by Martha A. Ramirez, Adrian A. Arellano, Fang Xie, Elizabeth A. Benavides, Robin A. Katchko, Luis Ayala, Alexandra Calderon, Rita A. Flores, Jean M. Escudero,…
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Quick ViewMucopolysaccharidoses (MPS) are caused by a deficiency of lysosomal enzyme activities needed to degrade glycosaminoglycans (GAGs), which are long unbranched polysaccharides consisting of repeating disaccharides. GAGs include: Chondroitin sulfate (CS), dermatan sulfate (DS), heparan sulfate (HS), keratan sulfate (KS), and hyaluronan. Their catabolism may be blocked singly or in combination depending on the specific enzyme…
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Quick ViewIn this compilation, the authors begin with a review of the mechanisms of synthesis and secretion, cellular effects and the involvement of serotonin (5-HT) in physiological and behavioral functions horses. In addition, the pathological conditions in which 5-HT is involved at the level of equine clinics are studied. Following this, the capabilities and limitations of…
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Quick ViewObesity is a major risk for both cardiovascular disease (CVD) and type 2 diabetes mellitus (T2DM). Obesity has reached epidemic proportions globally, and evidence suggests that the situation is likely to get worse in both developed and developing countries. It is considered to be a predisposing factor for several chronic diseases which include CVD, ischemic…
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Quick ViewThis book raises very important issues that concern the severe hypercholesterolemia phenotype. The severe hypercholesterolemia phenotype such as familial hypercholesterolemia (FH) is characterised by increased plasma low density lipoprotein (LDL) cholesterol concentration above 190 mg/dl, regardless of the cause. The majority of patients with FH present mutations in genes controlling LDL concentration, such as genes…
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