Gastric Peritoneal Carcinomatosis: Principles of Surgery and Treatment Options

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Fernando López Mozos, Md, PhD. (Editor) – Associate Professor, Chief of Upper Gastrointestinal and Peritoneal Oncology Surgery Unit, Hospital Clínico Universitario, Valencia, Spain
Roberto Martí Obiol, Md, PhD. (Editor) – Staff Surgeon, Upper Gastrointestinal and Peritoneal Oncology Surgery Unit, Hospital Clínico Universitario, Valencia, Spain

Series: Cancer Etiology, Diagnosis and Treatments

BISAC: MED062000

Target Audience: Surgeons, Residents of surgery, Surgical Oncologists, Oncologists, Radiologists, Pathologists, Medical Students

Gastric cancer is the fourth most common cancer in the world. Most gastric cancers are diagnosed in advanced stages, and the prognosis remains poor. The 5-year survival rate is 40-60% in eastern countries and around 25% in the west. Among advanced gastric cancer cases, peritoneal implantation is one of the most common forms of metastasis and around 14% of cases present peritoneal metastases at initial diagnosis, presenting a survival of 3-6 months. Until the early 1990s it was considered a terminal disease. But today these patients have some opportunities to be treated with curative intent or to prolong their life. Although the prognosis remains poor, there are some treatment options including cytoreductive surgery, neoadjuvant therapy, and some forms of intraperitoneal chemotherapy with or without hyperthermia. These are aggressive treatments, so we must be careful when selecting patients. Imaging and preoperative staging are also crucial in selecting patients for appropriate treatment. The surgical technique is described and a detailed demonstration video is available in the e-book version. New forms of treatment such as PIPAC and new scientific advances and future perspectives are discussed. This book is an update on this topic and attempts to provide an overview for all medical personnel involved in the treatment of these patients.

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Preface

Chapter 1. Epidemiology of gastric cancer
(R. Martí, R. Martí, F.López – Hospital Clínico Universitario, Valencia, Spain)

Chapter 2. Role of imaging in peritoneal surface malignancies
(A. Vera, A.  Alcolado, S. Torondel – Hospital Clínico Universitario, Valencia, Spain)

Chapter 3. Diagnosis and staging in advanced gastric cancer
(Benjamin L. Green, Jeremy L. Davis – Center for Cancer Research, National Cancer Institute, Bethesda, Washington, USA) )

Chapter 4.Histopathological and molecular classifications of gastric cancer
(C. Martinez-Ciarpaglini,  C. Alfaro-Cervelló, L. Alarcon, T. Fleitas – Hospital Clínico Universitario, Valencia, Spain)

Chapter 5. Patient selection and preoperative considerations
(M.E. Barrios, M.C. Fernández, R. Martí – Hospital Clínico Universitario, Valencia, Spain)

Chapter 6. Neoadjuvant and adjuvant therapy
(M. Huerta, V. Gambardella , T. Fleitas – Hospital Clínico Universitario, Valencia, Spain)

Chapter 7. Principles of cytoreductive surgery
(P. Barrios , I. Ramos , L. Bijelic – Hospital de Sant Joan Despí Moisès Broggi, Sant Joan Despí, Barcelona, Spain)

Chapter 8. Role of intraperitoneal chemotherapy.
(I. Manzanedo and F. Pereira – Hospital de Fuenlabrada – Madrid, Spain)

Chapter 9. Current role of PIPAC in peritoneal metastases of gastric origin
(M.C. Fernández, M.E. Barrios, F. López – Hospital Clínico Universitario, Valencia, Spain)

Chapter 10.Scientific Advances and future perspectives
(A. Saif,  A. Blakely – Center for Cancer Research, National Cancer Institute, Bethesda, Washington, USA)

Index

Additional information

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