A Closer Look at Fibroblasts

Justin O’Shane (Editor)

Series: Cell Biology Research Progress
BISAC: SCI017000

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Volume 10

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Special issue: Resilience in breaking the cycle of children’s environmental health disparities
Edited by I Leslie Rubin, Robert J Geller, Abby Mutic, Benjamin A Gitterman, Nathan Mutic, Wayne Garfinkel, Claire D Coles, Kurt Martinuzzi, and Joav Merrick

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A Closer Look at Fibroblasts first summarizes the molecular mechanisms of fibroblasts induced by photobiomodulation, reviewing current therapeutic approaches. Photobiomodulation, previously called low intensity laser irradiation, is a safe and efficient mechanism used to stimulate a positive response through absorbed light or light emitting diodes, and to reduce pain and inflammation promoting healing of the wound area.

Following this, the authors demonstrate the importance of fibroblasts in the process of development and progression of ovarian cancer, helping to establish new therapeutic management targeted towards cancer-associated fibroblasts.
In the penultimate study, the effects of the combination of andiroba, copaíba and guarana in the form of biphasic oil and emulsion is examined in the context of wound healing.

The concluding study focuses on the implications of the previously mentioned guarana in the context of skin aging and the oxy-inflammatory metabolism.
(Imprint: Nova)

Preface

Chapter 1. Molecular Mechanism of Photobiomodulation Associated with Fibroblasts
(Sandra M. Ayuk, DTech, and Heidi Abrahamse, PhD, Laser Research Centre, University of Johannesburg, Johannesburg, South Africa)

Chapter 2. The Role of Fibroblasts in Ovarian Cancer
(Rosekeila Simões Nomelini, Isa Beatriz Carminatti Batista, Simone Paula Queiroz, Ana Carolinne da Silva and Eddie Fernando Candido Murta, Research Institute of Oncology, Department of Gynecology and Obstetrics, Federal University of Triângulo Mineiro, Uberaba, MG, Brazil)

Chapter 3. Analysis of the Effect of an Andiroba, Copaíba and Guaraná Combination on in Vitro and in Vivo Scar Models
(Euler Esteves Ribeiro Filho, Bárbara Osmarin Turra, Bruna Chitolina, Beatriz Sadigursky Cunha, Cibele Ferreira Teixeira, Verônica Farina Azzolin, Ednea Aguiar Maia Ribeiro, Euler Esteves Ribeiro, Raquel de Souza Praia, Juscimar Carneiro Nunes, Ivana Beatrice Mânica da Cruz and Fernanda Barbisan, Universidade Federal do Amazonas, Manaus, Amazonas, Brazil, and others)

Chapter 4. Laser Therapy Associated With Guaraná as a Therapeutic Alternative on the Skin of Oxy-Inflammatory Metabolism
(Daíse Raquel Maldaner, MD, Cibele Ferreira Teixeira, MD, Marta Maria Medeiros Frescura Duarte, PhD, Verônica Farina Azzolin, PhD, Ivana Beatrice Mânica da Cruz, PhD, Ednea Aguiar Ribeiro, PhD, Neida Luiza Pellenz, PhD, and Fernanda Barbisan, PhD, Universidade Luterana do Brasil, Campus Santa Maria
Santa Maria, RS, Brazil, and others)

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