Wound Healing: Cellular Mechanisms, Alternative Therapies and Clinical Outcomes

Lacie E. Wade (Editor)

Series: Public Health in the 21st Century
BISAC: MED078000




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Non-steroidal anti-inflammatory drugs (NSAIDs) are among the most widely used drugs for the suppression of inflammation and pain. However, the therapeutic uses of NSAIDs are frequently limited by the significant negative side effects including ulceration, most notably in the gastrointestinal tract. This book examines alternative therapies to healing wounds such as negative pressure wound therapy; and the use of honey and biomaterials. The book also examines the implications of involvement of NSAID-activated gene 1 in ulceration and wound healing.

(Imprint: Nova Biomedical)


Chapter 1 - The Use of Negative Pressure Wound Therapy in Children: An Updated Review (pp. 1-24)
Fariha Sheikh, MD, Irving J. Zamora, MD, MPH and Oluyinka O. Olutoye, MD, PhD (Division of Pediatric Surgery, Michael E. DeBakey Department of Surgery, Baylor College of Medicine, Texas Children’s Hospital, Houston, TX, USA)

Chapter 2 - Reduction of Profibrotic Connective Tissue Growth Factor in Wounded Rat Corneas Using a Ribozyme Expressed in Self Complimentary Adeno-Associated Virus (pp. 25-42)
P. M. Robinson, S. S. Kim, S. Sriram, S. Tuli, W. W. Hauswirth, A. S. Lewin and G. S. Schultz (OB/GYN, Ophthalmology, Molecular Genetics and Microbiology, University of Florida, Gainesville, FL, USA)
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Chapter 3 - Honey and Wound Healing: New Solutions from an Old Remedy (pp. 43-48)
Simona Martinotti, Giorgio Calabrese and Elia Ranzato (University of Piemonte Orientale, DiSIT - Dipartimento di Scienze e Innovazione Tecnologica, viale Teresa Michel, Alessandria, Italy, and others)

Chapter 4 - Biomaterials for Wound-Healing Applications (pp. 49-104)
Pornanong Aramwit, Pharm.D., Ph.D. (Department of Pharmacy Practices, Faculty of Pharmaceutical Sciences, Chulalongkorn University, Bangkok, Thailand)

Chapter 5 - Implications of Involvement of NSAID-Activated Gene 1 in Ulceration and Wound Healing: Lessons from the Oncological and Cardiovascular Studies (pp. 105-122)
Yuseok Moon (Laboratory of Mucosal Exposome and Biomodulation, Department of Biomedical Sciences, Pusan National University School of Medicine, Yangsan, Korea, and others)


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