Vitamin C: Its Antioxidant Effects on Periodontitis

Daisuke Ekuni, Takaaki Tomofuji, Koichiro Irie, Tetsuji Azuma, Naofumi Tamaki, Tatsuo Yamamoto and Manabu Morita (Editors)
Okayama University, Japan, and others

Series: Nutrition and Diet Research Progress
BISAC: MED060000



Volume 10

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Special issue: Resilience in breaking the cycle of children’s environmental health disparities
Edited by I Leslie Rubin, Robert J Geller, Abby Mutic, Benjamin A Gitterman, Nathan Mutic, Wayne Garfinkel, Claire D Coles, Kurt Martinuzzi, and Joav Merrick


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Oxidative stress is involved in the pathogenesis of periodontitis. The effects of a variety of antioxidants on the prevention and treatment of periodontitis have been examined in animal studies. Vitamin C is a well-known water-soluble vitamin having antioxidant, anticarcinogenic, and immunomodulatory actions. Epidemiological studies have indicated a negative association between plasma vitamin C levels and the severity of periodontitis.

A clinical study reports that the intake of grapefruit leads to an increase in plasma vitamin C levels and reduces gingival bleeding. Recent animal studies show that vitamin C intake improves oxidative damage of periodontal tissue and increases the level of serum vitamin C. This book presents research which suggests that an adequate level of vitamin C intake may function as an antioxidant therapy to control oxidative stress, and be clinically beneficial in suppressing the progression of human periodontitis. (Imprint: Nova Biomedical)



Role of Oxidative Stress in Periodontitis

Effects of Vitamin C on Experimental Periodontitis

Possibility of Vitamin C Therapy for Human Periodontitis

Limitations of Antioxidant Therapy




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