Table of Contents
Table of Contents
Abstract
Introduction
Method
Results
Discussion
Conclusion
Acknowledgements
References
Index
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Rafael Coveñas, Arturo Mangas, Dominique Bodet, Sebastien Duleu, Pilar Marcos and Michel Geffard
Institute of Neurosciences of Castilla y LeĂłn (INCYL), Salamanca, Spain, and others
Series: Animal Science, Issues and Research, Neurology – Laboratory and Clinical Research Developments
BISAC: SCI070000
In general, the metabolic roles played by vitamins are well known, but to date less is known about the anatomical localization of these substances in the mammalian brain. Using a highly specific antiserum directed against vitamin C, the distribution of vitamin C-immunoreactive structures in the monkey (Macaca fascicularis) brain was studied. Antibody avidity and specificity were checked using the ELISA method, and it was estimated that antibody avidity (IC50) was 10-7 M for anti-conjugated ascorbic acid antibodies.
Thus, using an immunoperoxidase technique that increases the immunohistochemical reaction product, no immunoreactive fibers containing vitamin C were found in the monkey brain, but a moderate density of vitamin C-immunoreactive cell bodies was observed in the primary somatosensory cortex (postcentral gyrus). (Imprint: Nova Biomedical)
Table of Contents
Abstract
Introduction
Method
Results
Discussion
Conclusion
Acknowledgements
References
Index
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