Table of Contents
Preface
Ackowledgments
Chapter 1. Epidemiology
Inês Teixeira Farinha, MD
Department Pneumology, Pulmonology Department, Coimbra Hospital and University Centre, Coimbra, Portugal
Chapter 2. Dyspnea in Spontaneous Acute Lung Injury: Pathophysiology
Catarina Carvalho Cordes Amaral Barata, MD
Centro Hospitalar Lisboa Occidental, Lisboa, Portugal
Chapter 3. Lung Mechanics and Inflammatory Response
Laura Expósito Calamardo, MD
Department of Cardiology, Hospital Virgen de la Luz, Cuenca, Spain
Chapter 4. Barotrauma, Volutrauma and Atelectrauma: Pathophysiology
Rosana Mara da Silva1 and Thales Cantelle Baggio2
1Respiratory Physiotherapist, Hospital Municipal Health Department Jaraguá do Sul (SC), Brazil
2Physician, Cardiovascular Surgeon, Intensive Care Physician, Hospital Jaraguá and Hospital São José, Jaraguá do Sul (SC), Brazil
Chapter 5. Barotrauma, Volutrauma and Atelectrauma: Pathophysiology
Aneesa S. Shahul1, MD, DM, DNB, EDARM, MRC and B. L. Parvathi2, MD
1Respiratory Medicine, Consultant Pulmonologist, AHRI, India
2Pulmonology Department, ESI Hospital, India
Chapter 6. Positive End-Expiratory Pressure and Ventilator-Induced Lung Injury: Mechanisms and Clinical Recommendations
Greta Zunino, MD1,2, Denise Battaglini, MD1, Paolo Pelosi, MD1,2 and Patricia R.M. Rocco3
1Anesthesia and Intensive Care, San Martino Policlinico Hospital, IRCCS for Oncology and Neurosciences, Genoa, Italy
2Department of Surgical Sciences and Integrated Diagnostics (DISC), University of Genoa, Genoa, Italy
3Laboratory of Pulmonary Investigation, Carlos Chagas Filho Institute of Biophysics, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil
Chapter 7. Time Course of Ventilator-Induced Lung Injury
Fernanda Ferreira Cruz1, MD, PhD, Paolo Pelosi2,3, MD and Patricia Rieken Macêdo Rocco1, MD, PhD
1Laboratory of Pulmonary Investigation, Carlos Chagas Filho Institute of Biophysics, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil
2Department of Surgical Sciences and Integrated Diagnostics, University of Genoa, Genoa, Italy
3Anesthesia and Intensive Care, San Martino Policlinico Hospital, IRCCS for Oncology and Neurosciences, Genoa, Italy
Chapter 8. Hyperoxic Acute Lung Injury: Pathophysiology
Martina Flora, MD, Anna Annunziata, MD, Lidia Atripaldi, MD and Giuseppe Fiorentino, MD
Division of Respiratory Physiopathology and Rehabilitation, A.O.R.N. “Dei Colli” – Monaldi Hospital, Naples, Italy
Chapter 9. Ventilatory Approaches and High-Flow Nasal Cannula: Clinical Implications
Dimitrios A. Lagonidis, MD, PhD
Intensive Care Unit German Oncologic Center, Limassol, Cyprus
Chapter 10. Ventilatory Mode Approaches
Mario Agreda Fernández, MD
Medical Health Science, Emergency Department, Hospital Universitario Ramón y Cajal., Madrid, Spain
Chapter 11. High Frequency Non-Invasive Ventilation
Deniz Heppekcan, MD
Intensive Care Department, Darica Farabi Training and Education Hospital Kocaeli, Turkey
Chapter 12. A Summary of Animal Studies and Clinical Implications
Alejandro Úbeda Iglesias1, MD, PhD and Irene Fernández Burgos2, MD
1Intensive Care Unit, Hospital Punta de Europa, Algeciras, Spain
2Intensive Care Unit, Hospital Regional Universitario de Málaga, Málaga, Spain
Chapter 13. Pathophysiology, Treatment and Prevention
Lucía Hinojosa Díaz, MD
Emergency Department, Río Hortega Hospital, Valladolid, Spain
Chapter 14. Non-Invasive Negative Pressure Ventilation and Prevention of Lung Injuries
Mohammad Sallam1, MD, Nikhil Patankar2, MD and Omar Alibrahim3, MD
1Boston Children’s Hospital, Harvard Medical School, Department of Pediatrics Boston, Massachusetts, USA
2Beacon Children’s Hospital, Beacon Health System, South Bend, Indiana, USA
3Duke University Medical Center, Duke Children’s Hospital, Department of Pediatrics, Division of Pediatric Critical Care Medicine, Durham, North Carolina, USA
Chapter 15. Ventilator-Induced Lung Injury in Preterm Infants
M. O’Reilly, PhD, and G. M. Schmölzer, MD, PhD
Centre for the Studies of Asphyxia and Resuscitation, Neonatal Research Unit, Royal Alexandra Hospital, Edmonton, Alberta, Canada
Department of Paediatrics, University of Alberta, Edmonton, Alberta, Canada
Chapter 16. Management and Prevention of Ventilator Lung Injury in Children and Neonates with CPAP
Mariana Miranda1, MD, Rebecca Mitting1, MbCHB MRCPCH and Padmanabhan Ramnarayan1,2, MD PhD
1Pediatric Intensive Care Unit, St. Mary’s Hospital, Imperial College Healthcare NHS Trust, London, UK
2Imperial College, London, UK
Chapter 17. Surfactant Therapy in Prevention of Lung Injury in Neonates
Erika Pineda1, MD, Hari Gourabathini2, MD and Omar Alibrahim3,4, MD
1Oishei Children’s Hospital, University of Buffalo, Department of Pediatrics, Division of Pediatric Critical Care Medicine, Buffalo, New York, USA
2Beacon Children’s Hospital Beacon Health System, South Bend, Idiana, USA
3Duke University Medical Center
4Duke Children’s Hospital, Department of Pediatrics, Division of Pediatric Critical Care Medicine, Durham, North Carolina, USA
Chapter 18. Lung-Protective Ventilation Strategies in Preterm Infants
M. O’Reilly1,2, PhD and G. M. Schmölzer1,2, MD, PhD
1Centre for the Studies of Asphyxia and Resuscitation, Neonatal Research Unit, Royal Alexandra Hospital, Edmonton, Alberta, Canada
2Department of Pediatrics, University of Alberta, Edmonton, Alberta, Canada
Chapter 19. Biological Markers of Ventilator-Associated Lung Injury: Experimental and Clinical Studies
Ricardo Belo Quita, MD
Pneumology Department, Centro Hospitalar e Universitário do Porto, Portugal
Chapter 20. Monitoring Techniques: The Pressure/Volume Curve
Riccardo La Rosa, MD, Savino Spadaro, MD, PhD and Gaetano Scaramuzzo, MD
Department of Translational Medicine, University of Ferrara, Ferrara, Italy
Chapter 21. Non-Invasive Ventilatory Support and Patient Self-Induced Lung Injury: Pathophysiology
Nermin Zerman, MD
Ahi Evran University Training and Research Hospital, Kirsehir, Turkey
Index
Editor’s ORCID iD
Antonio M. Esquinas – 0000-0003-0571-2050
