Type 2 Diabetes: Causes, Treatment and Preventive Strategies


Isidoros Calpis (Editor)
Stefanos Frangopoulos (Editor)

Series: Endocrinology Research and Clinical Developments, Metabolic Diseases – Laboratory and Clinical Research
BISAC: HEA039050

Type 2 diabetes is a major health problem reaching epidemic dimensions. It’s complications, micro- and macrovascular, have a great impact in health economics as well as in the diabetic patient’s quality of life. In this book, the authors present current research in the study of the causes, treatment and preventive strategies of type 2 diabetes. Topics include the molecular genetics of type 2 diabetes mellitus; the pharmacogenetics and personalized therapy of oral antidiabetic drugs; gastric bypass and sleeve gastrectomy as effective treatment strategies in obese patients with type 2 diabetes; ACP1 genetic variability; and the study of biomarkers for diabetes mellitus type 2 and the role of high dose thiamine. (Imprint: Nova Biomedical )

Table of Contents

Table of Contents


An Overview and Molecular Genetics of Type 2 Diabetes Mellitus
(Monisha Banerjee, Madhukar Saxena, Molecular & Human Genetics Laboratory, Department of Zoology, University of Lucknow, India)

Type 2 Diabetes: Causes, Treatment and Preventive Strategies
(Athanasia K. Papazafiropoulou, Marina S. Kardara, 3rd Department of Internal Medicine and Center of Diabetes, General Hospital of Nikaia “Ag. Panteleimon” Piraeus, Greece)

Pharmacogenetics and Personalized Therapy of Oral Antidiabetic Drugs
(Zhao-Qian Liu, Hong Sun, Institute of Clinical Pharmacology, Hunan Key Laboratory of Pharmacogenetics, Central South University, Changsha, Hunan, People’s Republic of China, and others)

Roux-en-Y Gastric Bypass and Sleeve Gastrectomy are Effective Treatment Strategies in Obese Individuals with Type 2 Diabetes Mellitus
(Richdeep S. Gill, Kevin Whitlock, David Al-Adra, Daniel W. Birch, Shahzeer Karmali, Department of Surgery, University of Alberta, Edmonton, Alberta, Canada, and others)

ACP1 Genetic Variability and the Development of Diabetes in Obese Subjects
(F. Gloria-Bottini, M. Banci, P. Saccucci, A. Neri, A. Pietroiusti, E. Bottini, A. Magrini, Department of Biopathology and Imaging Diagnostics, University of Rome, Tor Vergata, Rome, Italy, and others)

Treatment of Type 2 Diabetes: Adjustments to Changes in Insulin Resistance and Secretion and to Variations in Basal and Prandial Glucose along the Diabetes Continuum
(L. Monnier, C. Colette, Dr. Owens, Laboratory of Human Nutrition, University Institute of Clinical Research, Montpellier Cedex, France, and others)*

Study of Protein Biomarkers for Diabetes Mellitus Type 2 and Role of High Dose Thiamine on their Level
(Samreen Riaz, Department Bioscience Division, Faculty of Life Sciences, Department of Structural and Molecular Biology, University College London, United Kingdom, and others)*


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