Transcriptomics and their Importance

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Sarah Naiyer, PhD – Research Scientist, Department of Microbiology and Immunology, University of Illinois at Chicago, USA
Khalid Hussain Bhat, PhD – Assistant professor, Division of Basic Sciences and Humanities, FOA, Wadura, Sopore, SKUAST-Kashmir

Series: Cell Biology Research Progress; Genetics – Research and Issues
BISAC: SCI029000; SCI049000
DOI: https://doi.org/10.52305/IZBB7081

Transcriptomics refers to the study of the transcriptome, which is the complete set of RNA transcripts produced by the genome of a specific cell. This book provides an overview of the information that the transcriptome provides and how developments in transcriptomics has transformed our understanding of cell biology. This book is comprised of three parts. Part I serves as an introduction to describe the development of transcriptomics as a technique and the way by which it has enhanced our knowledge and provided a better understanding of the basic biology of cellular function. Part II of the book is written to understand the milestones and contributions of transcriptomics in understanding the dynamics of cancer biology. Part III provides an insight on how transcriptomics is helping us to understand microbes and host-pathogen interaction including bioremediation.

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Table of Contents

Preface

Chapter 1. The Nuts and Bolts in Transcriptomics
Sarah Naiyer¹ and Khalid Hussain Bhat²
¹Department of Microbiology and Immunology, University of Illinois at Chicago, Il, USA
²Division of Basic Sciences and Humanities, FOA, Wadura, Sopore, SKUAST-Kashmir, India

Chapter 2. Transcriptomics in Understanding the Basic Biology of the Cell
Mrigya Babuta¹ and Kunwar Somesh Vikramdeo²
¹Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA
²Mitchell Cancer Institute, University of South Alabama, Mobile, AL, USA

Chapter 3. Transcriptomics in Basic Cancer Biology
Meenu A. Qureshi¹, Tawseeq Abdullah¹,², Asiya Batool¹ and Nishawar Jan¹
¹Department of Biotechnology, Science Block, University of Kashmir, Hazratbal, Srinagar, Jammu and Kashmir, India
²Department of Biotechnology, Central University of Kashmir, Ganderbal, Jammu and Kashmir, India

Chapter 4. Single-Cell Transcriptomics in Cancer Stem Cells (CSCs): Implications in Carcinogenesis and Drug Resistance
Sonam Sinha¹, Abhilasha Sharma² and Hamidullah Khan³
¹Kashiv Biosciences, Block-B Opp. Apple Woods Township, Ahmedabad, Gujarat, India
²Department of Life Science, Gujarat University, Ahmedabad, Gujarat, India
³Department of Dermatology, University of Wisconsin-Madison, Madison, WI, USA

Chapter 5. Transcriptome: A Tool for Precision Oncology
Lalita Dwivedi¹ and Km Anjaly²
¹Biological Product division, Indian veterinary Research Institute, Bareilly, India
²School of Life Sciences, Jawaharlal Nehru University, New Delhi, India

Chapter 6. Role of Transcriptomics in Understanding the Dynamics of Host-Pathogen Interaction
Sekhu Ansari¹, Kasturi Roy² and Dharmendra Nath Bhatt³
¹Division of Pathology, Cincinnati Children’s Hospital, Cincinnati, Ohio, USA
²Department of Molecular Biology and Biotechnology, University of Kalyani, Nadia, West Bengal, India
³National Institute of Plant Genome Research, Jawaharlal Nehru University Campus, Aruna Asaf Ali Road, New Delhi, India

Chapter 7. Transcriptomics in Microbial Bioremediation
Bisma Rashid, Saima Shafi, Malik Asif Aziz, Zaffar Mehdi Dar, Khalid Hussain Bhat and Mushtaq Ahmad Malik
Division of Basic Sciences and Humanities, FoA, Wadura, Sopore, SKUAST-Kashmir, India

Chapter 8. Transcriptome Advances: From Conventional Breeding to Genome-Assisted Breeding
Saima Shafi¹, Bisma Rashid¹, Malik Asif Aziz¹, Zaffar Mehdi Dar¹, Khalid Hussain Bhat¹, Mushtaq Ahmad Malik¹ and Owais Ali Wani²
¹Division of Basic Sciences and Humanities, FOA, Wadura, Sopore, SKUAST-Kashmir, India
²Division of Soil Science, FOA, Wadura, Sopore, SKUAST-Kashmir, India

Index


Editor’s ORCID iD

Sarah Naiyer https://orcid.org/0000-0002-3961-5489