Transcriptome Analysis and Why it Matters


Sagarika Mishra, PhD – Bhubaneswar, India

Series: Systems Biology – Theory, Techniques and Applications; Life Sciences Research and Development
BISAC: SCI003000; SCI102000; SCI010000

The book is a compilation of broad applications of Transcriptomics in the current field of science and technology and its impact towards the developmental aspects of crop science and clinical applications. The book focuses on the recent advancements in RNA sequencing technologies and the socio-economic impact with generations of huge transcriptome datasets aimed towards crop improvement against biotic and abiotic stress. Nevertheless, it also discusses the impact of transcriptomics in clinical studies focusing on oncology and therapeutics. The book targets mainly the young minds and provides them a basic understanding of how the omics world is contributing towards developmental aspects of science. Again, the book also discusses the various pros and cons of the myriad of datasets generated by the advanced sequencing platforms. Specifically, Chapter 1, 2, and 6 broadly explain the applications of “Transcriptomics” towards studying various abiotic and biotic stress response studies in plants. Chapter 3 focuses on the importance of the transcriptome datasets in extremophiles and studying their adaptive nature for surviving against environmental cues. Similarly, chapter 4 and 5 along with 7 and 8 emphasize on the importance and advancements in legume crops and millets, respectively, some of which are selectively known to display essential traits against various stress conditions affecting their survival. Lastly, chapters 9 and 10 are based on the promising applications of human transcriptomic studies and its profound application in science aimed towards studying various neurological disorders, diseases, and further advancement in therapeutics. Overall, the book is helpful for researchers, students and academicians for getting a better understanding on the wider-range applications of “Transcriptomic Research.”

Table of Contents


Chapter 1. Plant Transcriptomics Unraveling Potential QTLs (Quantitative Trait Loci) in Crops Responding to Abiotic Stress
Éderson Akio Kido, Vinicius Torres Guerra, José Ribamar Costa Ferreira Neto and Ana Maria Benko-Iseppon
Department of Genetics, Federal University of Pernambuco, Recife, Pernambuco, Brazil

Chapter 2. The Importance of Transcriptomics in Plant Stress Response Studies
Bayram Ali Yerlikaya, Seher Yerlikaya and Musa Kavas
Ondokuz Mayıs University, Faculty of Agriculture, Department of Agricultural Biotechnology, Samsun, Turkey

Chapter 3. Understanding the Facets of Extreme Land Plant Adaptation from Transcriptome Analysis
Richa Srivastava1, Debankona Marik2, Subham Meher1, Lingaraj Sahoo1 and Ayan Sadhukhan2
Department of Bioscience and Bioengineering, Indian Institute of Technology, Guwahati, India
2Department of Bioscience and Bioengineering, Indian Institute of Technology, Jodhpur, India

Chapter 4. Transcriptomics in Legume Crops: A Look at How RNA-Seq Has Advanced Research in Legumes
Seema Pradhan and Ajay Parida
Institute of Life Sciences, NALCO Square, Chandrasekharpur, Bhubaneswar

Chapter 5. Transcriptome Analysis in Peanuts to Decipher Abiotic Stress Responses
Feba Jacob1, Rasmieh Hamid2 and Zahra Ghorbanzadeh3
Centre for Plant Biotechnology and Molecular Biology, Kerala Agricultural University, Thrissur, India
2Department of Plant Breeding, Cotton Research Institute of Iran (CRII), Agricultural Research, Education and Extension Organization (AREEO), Gorgān, Iran
3Department of Systems Biology ABRII Agricultural Research Education and Extension Organization (AREEO), Agricultural Biotechnology Research Institute of Iran, Karaj, Iran

Chapter 6. Applications of Transcriptomics in Understanding Plant Disease Resistance
Neethu K. Chandran and S. Sriram
ICAR-Indian Institute of Horticultural Research, Hessaraghatta Lake Post, Bengaluru, India

Chapter 7. Pearl Millet Transcriptomics in Response to Abiotic Stresses: Current Status and Future Prospects
Adhimoolam Karthikeyan1,2, Vellaichamy Gandhimeyyan Renganathan2,3, Murugan Karthikeyan3 and Natesan Senthil4
1Subtropical Horticulture Research Institute, Jeju National University, Jeju, South Korea
2Department of Biotechnology, Centre of Excellence in Innovation, Agricultural College and Research Institute, Tamil Nadu Agricultural University, Madurai, Tamil Nadu, India
3Department of Plant Breeding and Genetics, Agricultural College and Research Institute, Tamil Nadu Agricultural University, Madurai, Tamil Nadu, India
4Department of Plant Molecular Biology and Bioinformatics, Center for Plant Molecular Biology and Biotechnology, Tamil Nadu Agricultural University, Coimbatore, Tamil Nadu, India

Chapter 8. The Role of Transcriptomics Technology in Understanding Abiotic Stress Tolerance in Finger Millets
Debabrata Panda1, Aloukika Panda1, Prafulla K. Behera1, Suraj K. Padhy1 and Jayanta K. Nayak2
Department of Biodiversity and Conservation of Natural Resources, Central University of Odisha, Koraput, India
2Department of Anthropology, Central University of Odisha, Koraput, India

Chapter 9. Neurotranscriptomics: A Significant Approach
Payal Trivedi1, Anurag Singh2 and Prachi Srivastava1
1Amity Institute of Biotechnology, Amity University, Lucknow, Uttar Pradesh, India
2Department of Biochemistry, University of Lucknow, Lucknow, Uttar Pradesh, India

Chapter 10. Applications of Transcriptomics in Clinical Studies
Shrutika Sakpal1,2
1Amity Institute of Biotechnology, Amity University Rajasthan, Jaipur, Rajasthan, India
2Department of Biotechnology, Dr. Homi Bhabha State University,The Institute of Science, Fort, Mumbai, India


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