Toxoplasma gondii: Dangers, Life Cycle and Research

Sean L. Hall (Editor)

Series: Parasites and Parasitic Diseases
BISAC: MED103000

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Toxoplasma gondii is an obligate intracellular parasite that infects 10-20% of the overall population in the US with rates increasing with age. T. gondii infects most warm blooded animals where an antibody response is generated to control the infection, however, the parasite forms bradyzoite cysts in brain and muscle. It can only reproduce in felines where oocytes are excreted in the feces. Infection can occur by a variety of routes. In cats, infection occurs by eating infected prey, primarily rodents or birds. Infection in humans can occur by eating undercooked infected meat, handling infected cat feces, ingesting oocytes on unwashed fruits or vegetables, or drinking contaminated water. Another important route of infection is congenital infection. This book discusses the potential risks this parasitic infection may cause. It also reviews the parasite’s life cycle. (Imprint: Nova Biomedical)

Preface

Chapter 1. Neurologic and Neuropsychiatric Risks Associated with Toxoplasma gondii Infection
Jeffrey B. Eells (Department of Basic Sciences, College of Veterinary Medicine, Mississippi State University, MS, USA)

Chapter 2. Behavior Changes in Humans with Toxoplasmosis
Mariana Fachini Esperança, Weslen Fabricio Pires Teixeira, Breno Cayeiro Cruz, Luciana Prando, Natália Donegá Lisboa, Welber Daniel Zanetti Lopes, and Katia Denise Saraiva Bresciani (Departamento de Psicologia, Universidade Estadual Paulista (Unesp), Faculdade de Ciências de Bauru, São Paulo, Brazil, and others)

Chapter 3. Antimicrobial Activities of Macrophages and Toxoplasma gondii Evasion Mechanisms
Gabriel R. A. Cabral and Renato A. DaMatta (Laboratório de Biologia Celular e Tecidual, Universidade Estadual do Norte Fluminense Darcy Ribeiro, Campos dos Goytacazes, RJ, Brazil)

Chapter 4. Apoptotic Mimicry: A Common Escape Mechanism of Protozoan Parasites
Thiago A. T. dos Santos, Sergio H. Seabra and Renato A. DaMatta (Laboratório de Biologia Celular e Tecidual, Universidade Estadual do Norte Fluminense Darcy Ribeiro, Campos dos Goytacazes, RJ, Brazil, and others)

Chapter 5. Toxoplasma gondii Infection in Wild Felids
J. A. Gomez-Rios, K. Y. Acosta-Viana, Eugenia Guzman-Marin, A. Ortega-Pacheco, D.M. Guiris-Andrade, and M. Jimenez-Coello (Centro de Investigaciones Regionales “Dr. Hideyo Noguchi,” Universidad Autonoma de Yucatan, Merida Yucatan, Mexico, and others)

Index

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