Thiadiazoles: Advances in Research and Applications


Alberto Cohen (Editor)

Series: Chemistry Research and Applications
BISAC: SCI013040

Thiadiazoles: Advances in Research and Applications opens by discussing how, due to antioxidant properties, influence on muscarinic acetylcholine receptors, and inhibition of acetylcholinesterase activity, 1,2,4-thiadiazole-class compounds can be considered as potential drugs in the treatment of disorders connected with the central nervous system, such as Alzheimer’s disease.
An overall review of the synthesis, biological activity, solubility, lipophilicity, and membrane permeability of a number of 1,2,4-thiadiazole derivatives with different substituents in the structure is presented.
Additionally, the authors provide an overview of the applications of thiadiazoles in the corrosion inhibition of metals and alloys. A detailed review of the literature on thiadiazole derivatives as corrosion inhibitors for acidic and neutral environments for different metallic substrates is also provided.

Table of Contents

Table of Contents


Chapter 1. Design of Bioavailable Drugs on Basis of 1,2,4-Thiadiazoles: Solubility Improvement via Modification of Crystal Structure and Solvation Characteristics
(Artem O. Surov, Tatyana V. Volkova and German L. Perlovich, Department of Physical Chemistry of Drugs, G. A. Krestov Institute of Solution Chemistry, Ivanovo, Russia)

Chapter 2. Novel 1,2,4-Thiadiazole Derivatives: Biological and Physicochemical Properties and Their Improvement Using Cyclodextrins and Polymers
(Tatyana V. Volkova, Alexey N. Proshin and Irina V. Terekhova, Department of Physical Chemistry of Drugs, G. A. Krestov Institute of Solution Chemistry, Russian Academy of Sciences Ivanovo, Russia, and others)

Chapter 3. Recent Advances on Thiadiazoles as Potential Corrosion Inhibitors for Industrial Metals and Alloys
(Dheeraj Singh Chauhan, D. B. Tripathy, M. A. Quraishi and Ambrish Singh, Center of Research Excellence in Corrosion, Research Institute, King Fahd University of Petroleum and Minerals, Dhahran, Saudi Arabia, and others)


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