Therapy for Hepatocellular Carcinoma – Etiology and Treatment

Nobuhiro Ohkohchi, MD, PhD (Editor)
Department of Surgery, University of Tsukuba, Japan

Series: Cancer Etiology, Diagnosis and Treatments
BISAC: MED062000



Volume 10

Issue 1

Volume 2

Volume 3

Special issue: Resilience in breaking the cycle of children’s environmental health disparities
Edited by I Leslie Rubin, Robert J Geller, Abby Mutic, Benjamin A Gitterman, Nathan Mutic, Wayne Garfinkel, Claire D Coles, Kurt Martinuzzi, and Joav Merrick


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Hepatocellular carcinoma (HCC) is the most common disease in the primary malignant tumor of the liver. It is considered that the therapy for HCC is very troublesome because most of the HCC occur from the injured liver such as chronic hepatitis or cirrhosis. If the patients with HCC receive proper therapy for their stage of HCC and liver function, a long survival is expected. In this book, the up-to-date contents of etiology, diagnosis techniques, and various kinds of therapies for HCC are described. This book is very helpful for the medical staff that takes care of the patients with HCC.

The contents of this book include precise descriptions of the following: i) the etiology and epidemiology of HCC, ii) the diagnosis technique of CT and MRI, and the indications and results of the treatments, i.e., iii) radiofrequency ablation, iv) molecular-targeted therapy, v) surgical resection, vi) transplantation, vii) trans-arterial chemo-embolization, and radiotherapy. In addition, viii) proton beam therapy is introduced, which is a less invasive therapy for localized HCC. (Imprint: Nova Biomedical )


Chapter 1 - Epidemiology and Etiology of Hepatocellular Carcinoma (pp. 1-24)
Junichi Shoda, M.D., Ph.D., A.G.A.F. (Department of Gastroenterology, Faculty of Medicine, University of Tsukuba, Japan)

Chapter 2 - Diagnosis of Hepatocellular Carcinoma Using CT and MRI (pp. 25-60)
Katsuhiro Nasu, M.D., Manabu Minami, M.D., Kensaku Mori, M.D., Masato Sugano, M.D., Yukio Morishita, M.D. and Yoshifumi Kuroki, M.D. (Department of Radiology, Faculty of Medicine, University of Tsukuba, Japan and others)

Chapter 3 - Clinical Staging and Treatment Selection for Hepatocellular Carcinoma: Overview of the Current Status and Perspectives for the Future (pp. 61-100)
Masato Abei, M.D., Ph.D. (Department of Gastroenterology, Faculty of Medicine, University of Tsukuba, Japan)

Chapter 4 - Hepatic Resection for Hepatocellular Carcinoma (pp. 101-126)
Kiyoshi Fukunaga, Keisuke Kohno and Nobuhiro Ohkohchi, M.D., Ph.D. (Department of Surgery, Faculty of Medicine, University of Tsukuba, Japan)

Chapter 5 - Transplantation for Hepatocellular Carcinoma (pp. 127-158)
Naoki Kawagishi, M.D. (Division of Transplantation, Reconstruction, and Endoscopic Surgery, Tohoku University Hospital, Japan)

Chapter 6 - Transcatheter Arterial Chemoembolization (pp. 159-242)
Shiro Miyayama (Department of Diagnostic Radiology, Fukuiken Saiseikai Hospital, Japan)

Chapter 7 - Proton Beam Therapy for Hepatocellular Carcinoma (pp. 243-308)
Hideyuki Sakurai, Toshiyuki Okumura, Nobuyoshi Fukumitsu, Hitoshi Ishikawa, Kayoko Ohnishi, Masashi Mizumoto, Toshiyuki Terunuma, Hiroaki Kumada and Takeji Sakae (Proton Medical Research Center, University of Tsukuba, Japan)


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