Table of Contents
Preface
Chapter 1. The Adaxonal Myelin Layer Triggers and Destabilizes Multiple Sclerosis Pathogenesis.
Chapter 2. Pathogenic Systems of Heterogeneity in Distinct Onset versus Progression Phases of Multiple Sclerosis in Terms of Amplifying Overlap of Immune Reactivities
Chapter 3. Variability of Expressivity in Multiple Sclerosis Involves Pathogenic Diversity in Lesion Progression and in Attempted Lesion Reconstitution
Chapter 4. Tightly Coupled Demyelination and Remyelination Constitute Basic Biology of Persistence in the Multiple Sclerosis Plaque in Terms of Neuronal/axonal Primal Injury Progression
Chapter 5. The Essential Links between Genetic Susceptibility and Environmental Pathogens in Multiple Sclerosis Progression and Initiation
Chapter 6. Performance Reactivation of Immune Response Defines Multiple Sclerosis Progression as Systems of Overlap Spread and Amplification via Endothelial Cells
Chapter 7. A Multi-Factorial Genesis of the Multiple Sclerosis Triggering Event and of the Propagation of Progressing Lesions in the Central Nervous System
Chapter 8. Attributes of Patterned Injury in Multiple Sclerosis Sequential Plaque Definition—the Primal Vascular Wall Paradigm
Chapter 9. Integral Biologic System-Induced Energy Failure Allows and Further Establishes Neurodegeneration and Inflammatory Demyelination in Multiple Sclerosis
Chapter 10. Constitutive and Acquired Formulas of Transformation in Multiple Sclerosis
Chapter 11. The Outcome of the Individual Multiple Sclerosis Plaque as Pre-Determined Parameter in Disease Progression or Potential Recovery
Chapter 12. Elemental Context Definition in Integral Geography of Multiple Sclerosis Lesions
Chapter 13. An Integral Formulation of Targeting Combinations of the Innate and Adaptive Immune Systems in Ms in Terms of Activated Vasculitis
Chapter 14. Dimensions of Co-Operative Overlap of a Primal Autoimmunity of Contactual Repeated Antigenic Characterization in Multiple Sclerosis
Chapter 15. Autoimmunity as Specific Enhanced Response to Cell Injury in Multiple Sclerosis Persistence and Re-Modulation in Terms of the Gut Microbiota Reconstitutive Profiles
Chapter 16. Systems of Integrity as Interacting and Individual Subsystems in Multiple Sclerosis Networks in Terms of Cns Impaired Immune Privileged Status in Neuroinflammation
Chapter 17. Instability of the Inflammasome Induces Eventual Autoimmunity in Multiple Sclerosis
Chapter 18. Diversity in Injury Pathways Incorporated as Unitary Targeting Events in Multiple Sclerosis
Chapter 19. An Essential Permissive Microenvironment as Primarily Passive Accumulation of Multiple Sclerosis Lesion Byproducts Redefines Disease Pathogenesis
Chapter 20. Proposed Dynamics of Predetermination of Multiple Sclerosis Injury in Terms of Concurrent Potentiality for Recovery
Chapter 21. Interface Interactivities as Systemic Biology Reconstitution in Multiple Sclerosis
Chapter 22. Profiles of Transforming Activations of Immune Cells as Infiltrative Dimensions in Definition of T Cd4+ Helper Cells in Neuroinflammation of Multiple Sclerosis Type
Index
