Mark P. Simons, Kevin G. Leidal , Sally J. McCormick, Thomas S. Griffith and William M. Nauseef (Editors)
University of Iowa, Iowa City, IA, USA, and others

Series: Cell Biology Research Progress, Cancer Etiology, Diagnosis and Treatments
BISAC: MED062000

Most bladder tumors are non-muscle invasive at diagnosis and have a high rate of local recurrence and progression even after local surgical therapy. Thus, many patients require lifelong follow-up examinations that include additional prophylactic treatments in the event of recurrence. Despite over 30 years of clinical use, the anticancer mechanism of BCG in the treatment of bladder cancer has not been clearly defined.

Proteins located in the three distinct granule populations of mature PMN are compartmentalized concomitant with their synthesis during cell maturation, rather than being differentially segregated by localizing markers that target a specific protein to a particular granule. This new book presents research including the understanding PMN production, localization, and release of TRAIL which is important in the design of future BCG-based bladder tumor immunotherapy protocols. (Imprint: Nova Biomedical)