Table of Contents
Table of Contents
Preface
About the Editors
List of Contributors
CHAPTER 1
Neuropathological Phenotypes in Human Prion Disorders
(Gianluigi Zanusso, Sergio Ferrari and Salvatore Monaco, Department of Neurological and Movement Sciences, University of Verona, Verona, Italy)
CHAPTER 2
X-Ray Fiber Diffraction from Prions: Of Mice and Beta-Solenoids
(Holger Wille, Centre for Prions and Protein Folding Diseases and Department of Biochemistry, University of Alberta, Edmonton, Alberta, Canada)
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CHAPTER 3
Neurotoxicity in Prion Disease: Relationships with other Neurodegenerative Diseases and Outlooks for Therapeutic Intervention
(Cathryn L. Ugalde, Victoria A. Lawson, David I. Finkelstein and Andrew F. Hill, Department of Biochemistry and Molecular Biology, Bio21 Molecular Science & Biotechnology Institute, The University of Melbourne, Parkville, Victoria, Australia, and others)
CHAPTER 4
Glycosaminoglycans in Prion and Prion-like Diseases
(Tuane C.R.G. Vieira and Jerson L. Silva, Instituto Federal do Rio de Janeiro, Rio de Janeiro, Brazil, and others)
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CHAPTER 5
Complexity of Aggregation Pathway of α-synuclein
(Leonid Breydo and Vladimir N. Uversky, Department of Molecular Medicine, Byrd Alzheimer’s Research Institute, Morsani College of Medicine, University of South Florida, Tampa, FL, USA, and others)
CHAPTER 6
Structural Characterization of α-synuclein Amyloids
(Wolfgang Hoyer, Hamed Shaykhalishahi, Santhosh Ayalur-Karunakaran and Henrike Heise, Heinrich Heine University Düsseldorf, Institute of Physical Biology, Universitätsstraße, Düsseldorf, Germany, and others)
CHAPTER 7
Prion-Like Spreading of Aβ and tau Aggregates and their Relevance as Drivers of Pathology in Alzheimer’s Disease
(Giuseppe Di Fede, Marcella Catania and Fabrizio Tagliavini, Fondazione IRCSS “Carlo Besta” Neurological Institute, Division of Neurology V and Neuropathology, Milan, Italy)
CHAPTER 8
Tau Strains and their Propagation in Experimental Disease Models
(Kyle P. McHugh, Olga A. Morozova and David W. Colby, Department of Chemical and Biomolecular Engineering, University of Delaware, Newark, DE, USA)
CHAPTER 9
Prion-Like Mechanisms in Amyotrophic Lateral Sclerosis
(Leslie I. Grad, Edward Pokrishevsky and Neil R. Cashman, Department of Medicine (Neurology), Djavad Mowafaghian Centre for Brain Health, University of British Columbia, Vancouver BC, Canada)
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CHAPTER 10
Prions in Yeast: Thinking Outside of the Brain
(Polina Drozdova and Andrew Matveenko, Dept. of Genetics and Biotechnology, Saint Petersburg State University, St. Petersburg, Russia, and others)
CHAPTER 11
Functional Prions: The Case Study of Aplysia
(Eric R. Kandel, Zuckerman Mind Brain Behavior Institute, Department of Neuroscience, Kavli Institute for Brain Science, Howard Hughes Medical Institute
College of Physicians and Surgeons of Columbia University, New York State Psychiatric Institute, New York, NY, USA)
CHAPTER 12
Concluding Remarks
(Giuseppe Legname, Suzana Aulić and Gabriele Giachin, Department of Neuroscience, Scuola Internazionale Superiore di Studi Avanzati (SISSA), Trieste, Italy, and others)
Index
