The Pharmacological Guide to Sofosbuvir

Vijay Gayam, MD (Editor)
Interfaith Medical Center, SUNY Downstate University Hospital

Series: Pharmacology – Research, Safety Testing and Regulation
BISAC: MED071000

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$160.00

Volume 10

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Special issue: Resilience in breaking the cycle of children’s environmental health disparities
Edited by I Leslie Rubin, Robert J Geller, Abby Mutic, Benjamin A Gitterman, Nathan Mutic, Wayne Garfinkel, Claire D Coles, Kurt Martinuzzi, and Joav Merrick

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Chronic hepatitis C infection (HCV) has been a global health burden since its discovery in 1989. This book “The Pharmacologic Guide to Sofosbuvir” is the integrated reference book for all clinicians, researchers, and students dealing with HCV infection. Sofosbuvir is a backbone for the majority of direct‐acting antivirals (DAA) combination regimens for all HCV Genotypes infected patients. This is the first book that offers a concise and up-to-date review on Sofosbuvir including pharmacological profile and difficult-to-treat-specific populations such as cirrhotic patients, HCV Co-infection (HIV and/or hepatitis B infection), renal impairment, renal and liver transplant, hepatocellular cancer, previous treatment failure, psychiatric illness, and substance abuse.

The book also addresses evolving therapy, and future directions in the antiviral treatment of hepatitis C. Clinicians, residents, students, and physician assistants who like a prompt review of hepatitis C treatment and new developments in treatment for hepatitis C will receive the greatest advantage from this concise guide. Based on promising results from the previous and ongoing studies involving sofosbuvir; HCV will likely be the first chronic viral infection to be eradicated globally with combinations of DAA.

The authors, editors, and publishers have exerted every effort to ensure that drug selections and dosage outlined in this text are per current recommendations for hepatitis C treatment and practice at the time of publication.
(Imprint: Nova Medicine and Health)

Preface

Chapter 1. Pharmacological Principles of Sofosbuvir
(Ramakanth Pata, Pavani Garlapati, Srikanth Naramala, Venu Madhav Konala, Sreedhar Adapa and Vijay Gayam, Department of Internal Medicine, Interfaith Medical Center, Brooklyn, NY, US, and others)

Chapter 2. Sofosbuvir in Non-Cirrhotic Patients with Chronic Hepatitis C Infection
(Amrendra Kumar Mandal, Benjamin Tiongson, Eric O. Then, Vijay Gayam and Vinaya Gaduputi, Department of Internal Medicine, Interfaith Medical Center, Brooklyn, NY, US, and others)

Chapter 3. Initial Management Options Involving Sofosbuvir in Chronic Hepatitis C Infection with Liver Cirrhosis
(Vijay Gayam, Arshpal Gill, Ricky Lali, Pavani Garlapati, Eric O. Then, Srikanth Maddika and Vinaya Gaduputi, Department of Internal Medicine, Interfaith Medical Center, Brooklyn, NY, US, and others)

Chapter 4. Management of HCV Infection with Sofosbuvir-Based Regimens in Patients with Medical Co-Morbidities
(Amrendra Kumar Mandal, Jasdeep Singh Sidhu, Benjamin Tiongson, Pavani Garlapati, Pallav Patel and Vijay Gayam, Department of Internal Medicine, Interfaith Medical Center, Brooklyn, NY, US, and others)

Chapter 5. Management of Patients Co-infected with HCV/HIV and HCV/HBV
(Amrendra Kumar Mandal, Jasdeep Singh Sidhu, Benjamin Tiongson, Pavani Garlapati, Pallav Patel and Vijay Gayam

Chapter 6. Sofosbuvir Treatment of Hepatitis C in People with Psychiatric Illness and Substance Use Disorders
(Benjamin Tiongson, Oluwole Jegede, Olaniyi Olayinka, Pavani Garlapati, Amrendra Kumar Mandal, Vijay Gayam and Jason Hershberger, Department of Psychiatry and Behavioral Sciences, Interfaith Medical Center, 1545 Atlantic avenue, Brooklyn, NY, US, and others)

Chapter 7. Sofosbuvir and Chronic Hepatitis C Treatment Failure
(Arshpal Gill, Priya Batta, Amrendra Kumar Mandal, Pavani Garlapati, Vijay Gayam and Smruti Mohanty,
American University of Antigua, Osbourn, Antigua and Barbuda, and others)

Index

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