The Omega-3 Fatty Acid Deficiency Syndrome: Opportunities for Disease Prevention

Robert McNamara (Editor)
University of Cincinnati, College of Medicine, Cincinnati, OH, USA

Series: Nutrition and Diet Research Progress, Metabolic Diseases – Laboratory and Clinical Research
BISAC: HEA017000

History has repeatedly taught us that diet-dependent nutrient deficiencies can cause a constellation of adverse symptoms (a syndrome) that are treatable and preventable by replacing the nutrient in the diet. Mammals are completely dependent on their diet to maintain optimal levels of long-chain omega-3 (LCn-3) fatty acids in cellular membranes throughout the body. It has been estimated that LCn-3 fatty acids in typical western diets have declined over the last century, largely being replaced by omega-6 fatty acids. Individuals residing in western countries commonly exhibit tissue and breast milk LCn-3 fatty acid levels that are substantially lower than those observed in individuals residing in countries that regularly consume LCn-3 fatty acids. This book, written by experts from around the world, describes what is currently known about the relationship between LCn-3 fatty acid status and resilience to different diseases. The goal of this book is to raise awareness of the importance of LCn-3 fatty acids in human health and their potential to increase resilience to several common diseases. (Imprint: Nova Biomedical )


This product is currently out of stock and unavailable.

Table of Contents

Table of Contents

Editorial – The Omega-3 Deficiency Syndrome

Section I. Omega-3 Fatty Acid Status: Gene-Diet Interactions

Chapter 1. Microsomal Biosynthesis of Omega-3 Fatty Acids
(Holly T. Reardon and J. Thomas Brenna, Cornell University, Ithaca, NY, USA)

Chapter 2. Peroxisomal Biosynthesis of Omega-3 Fatty Acids and Human Peroxisomal Diseases
(Ronald J.A. Wanders, University of Amsterdam, Academic Medical Centre, Departments of Clinical Chemistry and Pediatrics, Emma Children’s Hospital, Laboratory Genetic Metabolic Diseases, AZ, Amsterdam, The Netherlands)

Chapter 3. Docosahexaenoic Acid: The Brain Selective Omega-3 Fatty Acid that Facilitated Human Brain Evolution
(Stephen C. Cunnane, Research Center on Aging, Departments of Medicine and Physiology and Biophysics, Université de Sherbrooke, Sherbrooke, Québec, Canada)

Chapter 4. The Evolution of Omega-3 Fatty Acids in the Human Diet
(Leah G. Gillingham and Peter J.H. Jones, Richardson Centre for Functional Foods and Nutraceuticals, Department of Human Nutritional Sciences, University of Manitoba, Winnipeg, Manitoba, Canada)

Chapter 5. Omega-3 Fatty Acid Deficiency, Increased Omega-6/Omega-3 Ratio, and Disease Risk
(Artemis P. Simopoulos, The Center for Genetics, Nutrition and Health
Washington DC, USA)

Section II. Peripheral Tissue Diseases

Chapter 6. Omega-3 Fatty Acid Deficiency and Psoriasis
(Janelle Rachel Ricketts and Jane M. Grant-Kels, Dermatology Department, University of Connecticut Health Center, Farmington, CT, USA)

Chapter 7. Omega-3 Fatty Acid Deficiency and Osteoporosis
(Andrea Artoni, Fulvio Lauretani, Antonio Cherubini, Gian Paolo Ceda, and Marcello Maggio, Department of Internal Medicine and Biomedical Sciences, Section of Geriatrics, University of Parma and Geriatric Clinic Unit, Geriatric-Rehabilitation Department, University Hospital, Parma, Italy and others)

Chapter 8. Omega-3 Fatty Acid Deficiency and Sarcopenia
(Bettina Mittendorfer, Center for Human Nutrition, Washington University School of Medicine, Saint Louis, MO, USA)

Chapter 9. Omega-3 Fatty Acid Deficiency and Type 2 Diabetes Mellitus
(Darshan S. Kelley and Kent L. Erickson, Western Human Nutrition Research Center, ARS, USDA, and Department of Nutrition, University of California, Davis, CA, USA)

Chapter 10. Omega-3 Fatty Acid Deficiency and Rheumatoid Arthritis
(Phillip C. Calder, Human Development and Health Academic Unit, Faculty of Medicine, University of Southampton, IDS Building, MP887 Southampton General Hospital, Southampton, UK

Chapter 11. Omega-3 Fatty Acid Deficiency and Cardiovascular Disease
(Thomas A. Barringer and William S. Harris, UNC School of Medicine, Chapel Hill, NC, USA and others)

Chapter 12. Role of Omega-3 Fatty Acids in Weight Loss and Maintenance
(Manohar L. Garg and Lisa G. Wood, Nutraceuticals Research Group, School of Biomedical Sciences and Pharmacy, University of Newcastle, Callaghan, NSW, Australia)

Chapter 13. Omega-3 Fatty Acids – Opportunity for Cancer Prevention?
(Martina Wendel, Thom Thi Vu, and Axel R. Heller, Department of Child and Adolescent Psychiatry, Zentrum für Psychiatrie Südwürttemberg, Ravensburg, Germany and others)

Section III. Central Nervous System Disorders

Chapter 14. The Putative Role of Long-Chain Polyunsaturated Fatty Acids for Prevention and Treatment of Retinal Diseases
(John Paul SanGiovanni, Clinical Trials Branch, National Eye Institute, National Institutes of Health, NIH Clinical Center, Bethesda, MD, USA)

Chapter 15. Omega-3 Fatty Acids, Neurocognitive Development and Attention Deficit Hyperactivity Disorder
(Rachel V. Gow, Department of Child and Adolescent Psychiatry, Institute of Psychiatry, King’s College, London, UK)

Chapter 16. Role of Omega-3 Fatty Acids in Mood Disorders
(Kuan-Pin Su and Vicent Balanzá-Martínez, School of Medicine and Graduate Institute of Neural and Cognitive Sciences, China Medical University, Department of Psychiatry and Mind-Body Research Center (MBI-Lab), China Medical University Hospital, Taichung, Taiwan and others)

Chapter 17. Pathological and Therapeutic Implications of Omega-3 Fatty Acids in Schizophrenia
(Jeffrey K. Yao, Ravinder Reddy, Ruth Condray, Tao Long and Gretchen Haas, VA Pittsburgh Healthcare System, Pittsburgh, PA, USA and others)

Chapter 18. Omega-3 Fatty Acids in Alzheimer’s Disease: Opportunity for Prevention and Early Intervention
(Ricardo Palacios Pelaez and Nicolas G. Bazan, Diater Laboratories, S.A., Madrid, Spain and others)

Section IV. Approaches and Standards

Chapter 19. Standardizing Methods for Assessing Omega-3 Fatty Acid Biostatus
(William S. Harris, Clemens von Schacky and Yongsoon Park, OmegaQuant, LLC, and Sanford School of Medicine, University of South Dakota, Sioux Falls, SD, USA and others)

Chapter 20. Standards for the Prevention and Treatment of Omega-3 Fatty Acid Deficiency
(Connye N. Kuratko and Norman Salem, Jr., DSM Nutritional Products, Columbia, MD, USA)



Publish with Nova Science Publishers

We publish over 800 titles annually by leading researchers from around the world. Submit a Book Proposal Now!