The Medulloblastoma Book


Series: Neuroscience Research Progress
BISAC: MED057000

This book is a unique insight into the medulloblastoma, and it provides both a broad review and detailed information. It starts with the history of medulloblastoma as a term and a distinct entity in nosology, and then it explores in-depth the diagnosis, genetics, neurosurgical and oncological management of medulloblastoma patients, their outcome, and long-term complications.

Also discussed are novel therapies and next generation clinical trials. This landmark text is written by leading authorities in research and treatment of medulloblastoma. It provides information based on clinical trials, major clinical series, and the outstanding experience and knowledge of the authors. It contains many great illustrations, which help the reader to understand the new knowledge easily. It also includes authoritative and expert opinions and advice regarding the treatment and management of the patients with medulloblastoma. This will help readers avoid mistakes and achieve good results during the management of their patients.

This book is useful to medical specialists such as paediatricians, radiologists, neurosurgeons, and oncologists who want to be updated in an integrated way about the current knowledge of medulloblastoma. It is also an excellent tool for medical students, nurses, residents, and young researchers who are interested in medulloblastoma and neuro-oncology.

This book aims to enrich the medical literature throughout the world by providing an integrated knowledge of medulloblasoma in a comprehensive and practical way, as it is written by scientists who work at the cutting-edge of their specialities. (Imprint: Nova Biomedical )


Table of Contents

Table of Contents


Chapter 1. Introduction to Medulloblastoma
(Dimitris A. Kombogiorgas, Department of Neurosurgery, HMG Al Qassim Hospital, Kingdom of Saudi Arabia)

Chapter 2. Histopathology and Molecular Pathology of Medulloblastoma
(Manila Antonelli, Francesca Romana Buttarelli, Felice Giangaspero, Deptartment of Radiological, Oncological and Anatomo-pathological Sciences, University Sapienza Rome, Italy, and others)

Chapter 3. Genetics of Medulloblastoma
(Abhinav Dey, Anshu Malhotra, Meghan Connor Buss, Juhyun Lee, BS, Anna Marie Kenney, Robert Craig Castellino, Aflac Cancer & Blood Disorders Center, Children’s Healthcare of Atlanta, Department of Pediatrics, Emory University School of Medicine, Atlanta, GA, USA)

Chapter 4. Imaging of Medulloblastoma
(Korgun Koral, Department of Radiology, University of Texas Southwestern Medical Center and Children’s Medical Center, Dallas, Texas, USA)

Chapter 5. Surgical Treatment of Medulloblastoma
(Stephanie Puget, Dimitris A. Kombogiorgas, Thomas Blauwblomme, Michel Zerah, Christian Sainte-Rose, AP-HP, Hôpital Necker Enfants Malades, Department of Pediatric Neurosurgery, Paris, France; Université Paris Descartes, Sorbonne Paris Cité, France, and others)

Chapter 6. Radiotherapy in the Management of Medulloblstoma
(Niccolo Giaj Levra, Frank Saran, Department of Oncology, Radiation Oncology, Azienda Ospedaliera Citta’ della Salute e della Scienza, University of Torino, Turin, Italy, and others)

Chapter 7. Toxicity of Radiotherapy in the Treatment for Medulloblastoma
(Rachael Lester, Nadia Laack, Department of Radiation Oncology, Mayo Clinic, Mayo School of Medicine, Rochester, MN, USA, and others)

Chapter 8. Chemotherapy of Medulloblastoma
(Asher M. Marks, Eugene I. Hwang, Roger J. Packer, Department of Pediatrics, Section of Hematology-Oncology, Yale School of Medicine, New Haven, Connecticut, USA and others)

Chapter 9. Metastatic Medulloblastoma: Clinical and Biological Insights
(Vijay Ramaswamy, Marc Remke, Xiaochong Wu, Michael D. Taylor, Division of Neurosurgery, Arthur and Sonia Labatt Brain Tumour Research Centre, Hospital for Sick Children, Toronto, ON, Canada, and others)

Chapter 10. Intra-Cerebrospinal Fluid Therapy for Leptomeningeal Metastases in Medulloblastoma
(Lisethe Meijer, David Walker, Irene Slavc, Children’s Brain Tumour Research Centre, University of Nottingham, Nottingham, United Kingdom, and others)

Chapter 11. Outcome and Long-Term Complications
(Veronica Biassoni, Elisabetta Schiavello, Lorenza Gandola, Ettore Seregni, Alice Indini, Filippo Spreafico, Maura Massimino, Department of Pediatrics, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy, and others)

Chapter 12. Medulloblastoma in Developmental Age: Long-Term Neurocognitive and Emotional-Behavioral Outcome
(Daria Riva, Developmental Neurology Division, Fondazione IRCCS Istituto C.Besta, Milano, Italy)

Chapter 13. Neurocognitive Sequelae: Personal Experiences
(Geraldina Poggi, Annarita Adduci, Unit of Acquired Brain Injury, Scientific Institute E. Medea – Bosisio Parini (Lecco), Italy, and others)

Chapter 14. Medulloblastoma in Adulthood
(Laurent Riffaud, Department of Neurosurgery, Pontchaillou University Hospital, Rennes, France)

Chapter 15. Novel Therapies and Next Generation Clinical Trials in Medulloblastoma
(Claudia C. Faria, Roberto J. Diaz, James T. Rutka, Division of Neurosurgery and Labatt Brain Tumour Research Centre, The Hospital for Sick Children, University of Toronto, Canada)


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