The Innate Immune System in Health and Disease: From the Lab Bench Work to Its Clinical Implications. Volume 1

$230.00$276.00

Series: Immunology and Immune System Disorders
BISAC: MED047000; MED044000
DOI: https://doi.org/10.52305/KCVE8303

The aim of this book, The Innate Immune System in Health and Disease: From the Lab Bench Work to Its Clinical Implications. Volume 1, is to provide updated information to scientists and clinicians that is valuable in their quest to gather information, carry out new investigations, and develop novel drugs that are more effective and do not cause adverse effects targeting the innate immune system. This book is of high priority to people interested in an update on innate immunity. Volume 1 examines the participation of innate immunity in diseases such as infections by viruses, cancer, or parasites. Specifically, this volume discusses innate immunity as it relates to chronic HIV infection, type 2 diabetes, and SARS-CoV-2, as well as its relationship with vitamin D. The dual role of neutrophils in cancer development and the plasticity of natural killer cells are investigated. Also, the immune response to infections from helminth and Toxoplasma gondii are described.

The Innate Immune System in Health and Disease: From the Lab Bench Work to its Clinical Implications. Volume 1 promises to be a must-have book for all people who want to know about the role of the basic functioning of the innate immune system in several diseases of actual relevance to human health.

Key Features:
• Provides basic and clinical evidence based on molecular interactions to address the role of innate immunity in viral diseases, such as HIV and SARS-CoV-2
• Discusses the role of vitamin D as modulator of the immune response during viral infections
• Addresses the immunometabolic interactions in type 2 diabetes and SARS-CoV-2 infection (COVID-19)
• Analyzes the dual role for neutrophils and myeloid-derived suppressor cells in the development of colorectal cancer
• Provides evidence of the plasticity of natural killer cells in cancer and its opportunities for therapy
• Delves into the dual role of neutrophils in cancer development
• Presents updated information on innate immunity against Toxoplasma gondii infection
• Discusses in depth the role of the innate immune response during helminth infections

We hope that readers enjoy this book and that it may be of use to all people involved, from scientists in the lab to clinicians in the field.

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Table of Contents

Preface

Section I. Innate Immunity and Viruses

Chapter 1. Innate Immunity in Chronic HIV Infection: Relationship Between Viral Reservoir and Inflammatory Response and Its Clinical Implications
(Perla Mariana Del Río-Estrada, Enrique Espinosa and Mónica Viveros-Rogel – Instituto Nacional de Enfermedades Respiratorias (INER) Ismael Cosío Villegas, Centro de Investigación en Enfermedades Infecciosas, Mexico City, Mexicom, et al.)

Chapter 2. Vitamin D as a Modulator of the Immune Response During Viral Infections
(Georgina I. López-Cortés, Alejandro Magallanes-Puebla, Enrique Ortega – Departamento de Inmunología, Instituto de Investigaciones Biomédicas, Universidad Nacional Autónoma de México, México City, Mexico)

Chapter 3. Immunometabolic Interactions in Type 2 Diabetes and SARS-CoV-2 Infection (COVID-19)
(Rebeca Viurcos-Sanabria and Galileo Escobedo – Laboratory of Immunometabolism, Research Division, General Hospital of Mexico “Dr. Eduardo Liceaga,” Mexico City, Mexico, et al.)

Section II. Innate Immunity and Cancer

Chapter 4. A Dual Role for Neutrophils and Myeloid-Derived Suppressor Cells in the Development of Colorectal Cancer
(C. Ángel Sánchez-Barrera, J. Efraín Olguín and Luis I. Terrazas – Laboratorio Nacional en Salud, Facultad de Estudios Superiores Iztacala, Universidad Nacional Autónoma de México, Tlalnepantla, Estado de México, Mexico, et al.)

Chapter 5. Plasticity of Natural Killer Cells in Cancer: Opportunities for Therapy?
(Mariana Segovia-Mendoza and Jorge Morales-Montor – Departamento de Farmacología, Facultad de Medicina, Universidad Nacional Autónoma de México, Ciudad de México, México, et al.)

Chapter 6. The Dual Role of Neutrophils in Cancer Development
(Eileen Uribe-Querol and Carlos Rosales – Laboratorio de Biología del Desarrollo, División de Estudios de Posgrado e Investigación, Facultad de Odontología, Universidad Nacional Autónoma de México, Mexico City, Mexico, et al.)

Section III. Innate Immunity and Parasites

Chapter 7. Innate Immunity Against Toxoplasma gondii Infection
(Carmen T Gómez de León and Jorge Morales-Montor – Departamento de Inmunología, Instituto de Investigaciones Biomédicas, Universidad Nacional Autónoma de México, Ciudad de México, México)

Chapter 8. The Role of the Innate Immune Response During Helminth Infections
(Víctor Hugo Del Río-Araiza, Karen Elizabeth Nava-Castro and Jorge Morales-Montor – Departamento de Parasitología, Facultad de Medicina Veterinaria y Zootecnia, Universidad Nacional Autónoma de México, Ciudad de México, México, et al.)

Index

Additional information

Binding

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