Table of Contents

Table of Contents

Preface

Introduction

Acronyms and Abbreviations

Part I: General Considerations

Chapter 1 – From Lyell’s Syndrome to Toxic Epidermal Necrolysis (pp. 3-4)

Chapter 2 – The Keratinocyte, Major Target and Actor (pp. 5-10)

Chapter 3 – Immunological Mechanisms (pp. 11-12)

Part II: Clinico-Pathologic Features

Chapter 4 – Cutaneous and Mucosal Clinical Presentations (pp. 15-18)

Chapter 5 – Extracutaneous Involvement (pp. 19-28)

Chapter 6 – Histopathology (pp. 29-32)

Chapter 7 – Proteomic Kinetic Analysis (pp. 33-34)

Chapter 8 – Differential Diagnosis (pp. 35-44)

Chapter 9 – Drug Impact (pp. 45-46)

Chapter 10 – Pharmacogenetics (pp. 47-48)

Chapter 11 – Lymphocytic Impact (pp. 49-52)

Chapter 12 – Monocyte-Macrophage and Mesenchymal Cell Impact (pp. 53-54)

Chapter 13 – Keratinocyte Pathobiology and Demise (pp. 55-70)

Chapter 14 – Analytic Skin Biometrology (pp. 71-74)

Part III: Management

Chapter 15 – TEN Prevention (pp. 77-78)

Chapter 16 – Prognosticators (pp. 79-84)

Chapter 17 – Supportive Care Management (pp. 85-88)

Chapter 18 – Survival Management (pp. 89-90)

Chapter 19 – Topical Treatment (pp. 91-98)

Chapter 20 – Systemic Pharmacotherapy (pp. 99-106)

Chapter 21 – Tissue Replacement (pp. 107-108)

Chapter 22 – Cost-Effectiveness of Treatment (pp. 109-110)

Part IV: Framing the Future

Chapter 23 – Spotlight on Perspective (pp. 113-116)

References

Index

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Additional Information

Audience: Medical students, dermatologists, intensive care physicians, burn units, ophthalmologists.