The Book of Fungal Pathogens

$250.00

André Luis Souza dos Santos, PhD – Laboratory of Advanced Studies of Emerging and Resistant Microorganisms, General Microbiology Department, Microbiology Institute Paulo de Góes (IMPG), Health Center Science, Federal University of Rio de Janeiro, Brazil
Marta Helena Branquinha – Universidade Federal do Rio de Janeiro (UFRJ), Brazil
Lucimar Ferreira Kneipp – Fundação Oswaldo Cruz (FIOCRUZ), Brazil
Maryam Roudbary – Iran University of Medical Sciences, Iran

Series: Infectious Diseases and Microbiology; Recent Advances in Microbiology
BISAC: SCI094000; SCI045000; MED052000
DOI: 10.52305/RPUR9670

Fungi can be harmful to global health, biodiversity and agriculture and they are responsible for life-threatening diseases, especially in individuals with a weakened immune system. Over the last decades, the number of invasive infections, mainly caused by fungi belonging to Candida, Cryptococcus, Aspergillus and Pneumocystis genera has increased and negatively affected the clinical outcomes of the patients.

With regard to all these issues, this book focuses on the processes associated with fungal pathogenesis. The authors believe that this book will serve as a useful reference for consultations with specialists in the Mycology field since it contemplates the most important issues in the proposed area. The chapters are written by experts who actively contribute to international scientific literature. The editors also believe that the theme is a very attractive proposal, and the compilation of interesting data will benefit readers in terms of identification, epidemiology, pathogenesis, and treatment of predominant fungal infections around the world. “The Book of Fungal Pathogens” contains 18 chapters, several pictures, diagrams, and tables that can be used in both undergraduate and postgraduate teaching as well as scientific lectures.

Table of Contents

Preface

Chapter 1. Fungal Diseases and COVID-19
Ellie Rose Mattoon1, Radames JB Cordero2 and Arturo Casadevall2
1Krieger School of Arts and Sciences, Johns Hopkins University Baltimore, Maryland, USA
2Department of Molecular Microbiology and Immunology, Johns Hopkins Bloomberg School of Public Health, North Wolfe Street, Baltimore, USA

Chapter 2. New Aspects of Candida spp Infections
Fatemeh Nikoomanesh1,2, Maryam Roudbary3 and Farhad Saeif4
1Department of Medical Microbiology, School of Medicine, Birjand University of Medical Sciences,
Birjand, Iran
2Infectious Diseases Research Center, Birjand University of Medical Sciences, Birjand, Iran
3Deapartment of Parasitology and Mycology, School of Medicine, Iran University of Medical Sciences, Tehran, Iran
4Department of Immunology and Allergy, Academic Center for Education, Culture, and Research (ACECR), Tehran, Iran

Chapter 3. Pathogenesis of Oral Candidiasis: A Virulence Insight into Drug Discovery and New Treatments
Priscilla Guimarães Silva Vasconcelos1, Diego Romário-Silva2, Ernani Canuto Figueirêdo Júnior1, Jozinete Vieira Pereira1 and Edja Maria Melo de Brito Costa1
1Department of Dentistry, State University of Paraíba (UEPB), Campina Gande, PB, Brazil
2Research Program in Integrated Dental Sciences, University of Cuiabá (UNIC), Cuiabá, MT, Brazil

Chapter 4. Candida Auris, an Emerging Pathogen: Virulence, Current Diagnostic Approaches, and Therapeutic Options
Thayná Ellen de Sousa Alves Ferreira1, Andréa Cristina Barbosa da Silva2, Janaína de Cássia Orlandi Sardi1, Tahyna Duda Deps3, Paula Ribeiro Garcia3, Sindy Magri Roque4, Priscila Guimarães Silva Vasconcelos5, Edja Maria Melo de Brito Costa5 and Diego Romario-Silva1,3,*
1Graduate Program in Integrated Dental Sciences, School of Dentistry of the University of Cuiabá, Cuiabá, Brazil
2Department of Pharmacy, State University of Paraiba (UEPB), Campina Grande, PB, Brazil
3Faipe College, Cuiabá, Mato Grosso, Brazil
4School of Pharmaceutical Sciences, State University of Campinas, Campinas, SP, Brazil
5Department of Dentistry, State University of Paraíba, Campina Grande, Paraíba, Brazil

Chapter 5. Talaromyces Marneffei: Biology, Epidemiology, Diagnosis and Treatment
Mateusz Benkowski and Kevin Kavanagh
Department of Biology, Maynooth University, Maynooth, Co. Kildare, Ireland

Chapter 6. Outstanding Questions in the Field from the Curious Coccidioidomycosis
Raimunda Sâmia Nogueira Brilhante1, Marcos Fábio Gadelha Rocha1,2, José Júlio Costa Sidrim1
and Germana Costa Paixão1
1Department of Pathology and Legal Medicine, Federal University of Ceará, Fortaleza, Ceará, Brazil
2College of Veterinary, State University of Ceará, Fortaleza, Ceará, Brazil

Chapter 7. Sporotrichosis, the Fungal Disease Caused by Members of the Sporothrix Genus
Ximena Esquivias-Varela, Juan Mauricio Ibarra-Chavira, Laura C. García-Carnero, Manuela Gómez-Gaviria, Ana Paulina Vargas-Macías and Héctor Manuel Mora-Montes
Department of Biology, Universidad de Guanajuato, Guanajuato, Mexico

Chapter 8. Paracoccidioidomycosis: An Update from the Environment to Clinics
Haroldo Cesar de Oliveira1, Ana Carolina Alves de Paula e Silva2, Caroline Maria Marcos3, Julhiany de Fátima da Silva4, Liliana Scorzoni5,6, Patricia Akemi Assato7 and Suélen Andreia Rossi8
1Instituto Carlos Chagas, Fundação Oswaldo Cruz (Fiocruz-PR), Curitiba, Parana, Brazil
2Department of Dental Materials and Prosthodontics, Sao Paulo State University (UNESP), Araraquara, Sao Paulo, Brazil
3Department of Clinical Analysis, School of Pharmaceutical Sciences, São Paulo State University (UNESP), Araraquara, Sao Paulo, Brazil
4Department of Infectious Diseases, Dermatology, Diagnostic Imaging and Radiotherapy, Sao Paulo State University (UNESP), Botucatu, Sao Paulo, Brazil
5Department of Biosciences and Oral Diagnosis, Institute of Science and Technology, Department of Biosciences and Oral Diagnosis, Sao Paulo State University (UNESP), Sao Jose dos Campos, Sao Paulo, Brazil
6Nursing Post Graduation, Guarulhos University (UNG), Guarulhos, Sao Paulo, Brazil
7Department of Bioprocess and Biotechnology, School of Agricultural Sciences, São Paulo State University (UNESP), Botucatu, Sao Paulo, Brazil
8Department of Microbiology, Institute of Biomedical Sciences, University of Sao Paulo (USP), Sao Paulo, Brazil

Chapter 9. Dermatophytes and Dermatophytosis: A New Look at an Old Mycosis
Germana Costa Paixão,1,2, Marcos Fábio Gadelha Rocha1,2, José Júlio Costa Sidrim1 and Raimunda Sâmia Nogueira Brilhante1
1Department of Pathology and Legal Medicine, Federal University of Ceará, Fortaleza, Ceará, Brazil
2State University of Ceará, Fortaleza, Ceará, Brazil

Chapter 10. Some Rare and Endemic Fungal Species: The Cause of Difficult-To-Diagnose Community-Acquired Mycoses
Justus Amuche Nweze1,2,3, Julius Eyiuche Nweze1,2, Somtochukwu Cecilia Agbo4, Emeka Innocent Nweze4 and Emmanuel A. Eze4
1Department of Ecosystem Biology, Faculty of Science, University of South Bohemia in Ceske Budejovice, Ceske Budejovice, Czech Republic
2Institute of Soil Biology and Biogeochemistry, Biology Centre, Czech Academy of Sciences, Ceske Budejovice, Czech Republic
3Department of Science Laboratory Technology, Faculty of Physical Sciences, University of Nigeria, Nsukka, Enugu State, Nigeria
4Department of Microbiology, Faculty of Biological Sciences, University of Nigeria, Nsukka, Nigeria

Chapter 11. Purpureocillium lilacinum: From Environment to Emergent Human Pathogens
Danielly Corrêa-Moreira1,2, Cintia de Moraes Borba2 and Manoel Marques Evangelista Oliveira2
1Department of Education, Post-Doctoral in Clinical Research of Infectious Diseases, Evandro Chagas National Institute of Infectious Diseases, Fiocruz, Rio de Janeiro, Brazil
2Laboratory of Taxonomy, Biochemistry and Bioprospecting of Fungi, Oswaldo Cruz Institute, Fiocruz, Rio de Janeiro, Brazil

Chapter 12. The Genus Diaporthe: A Prolific Source of Novel Bioactive Metabolites
María Victoria Castelli, Nathalie Ruiz Mostacero, Cecilia Luisa Fulgueira and Silvia Noelí López
Farmacognosia, Universidad Nacional de Rosario – CONICET, Rosario, Argentina

Chapter 13. Taking a Break: Host-Fungi in a Distance Relationship
Pedro H. M. Bürgel, Lucas de O. Las-Casas and Anamelia L. Bocca
Laboratory of Applied Immunology, Institute of Biology, University of Brasília, Brasília, Federal District, Brazil

Chapter 14. Mycobiota Dysbiosis in Immune-Associated Pathologies
Fabianno Ferreira Dutra
Department of Immunology, Instituto de Microbiologia Paulo de Góes, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brasil

Chapter 15. Coronavirus Disease-2019 (COVID-19)-Positive Patients as Susceptible Hosts to Severe Fungal Coinfections
Heloisa Freire Frota1,2, Carolline Margot Albanez Lorentino1, Luca Mokus dos Santos1, Marcos Vinicius Santos1, Nahyara Louize Miranda Siqueira1, Maryam Roudbary3, Lucimar Ferreira Kneipp4,5, Marta Helena Branquinha1,5 and André Luis Souza dos Santos1,2,5
1Laboratório de Estudos Avançados de Microrganismos Emergentes e Resistentes (LEAMER), Departamento de Microbiologia Geral, Instituto de Microbiologia Paulo de Góes, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil
2Programa de Pós-Graduação em Bioquímica, Instituto de Química, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil
3Department of Parasitology and Mycology, School of Medicine, Iran University of Medical Sciences, Tehran, Iran
4Laboratório de Taxonomia, Bioquímica e Bioprospecção de Fungos, Instituto Oswaldo Cruz, Fundação Oswaldo Cruz, Rio de Janeiro, Brazil
5Rede Micologia RJ – Fundação de Amparo à Pesquisa do Estado do Rio de Janeiro (FAPERJ), Rio de Janeiro, Brazil

Chapter 16. Antifungal Resistance Mechanisms
Antonio Ferreira-Pereira1, José Alexandre da Rocha Curvelo1, Anna Lea Silva Barreto1,2, Daniel Clemente de Moraes1 and Levy Tenório Sousa Domingos1
1Laboratório de Bioquímica Microbiana, Departamento de Microbiologia Geral, Universidade Federal do Rio de Janeiro, Rio de Janeiro, RJ, Brazil
2Centro Universitário IBMR, Rio de Janeiro, RJ, Brazil

Chapter 17. Drug Delivery Systems Targeting Fungal Brain Diseases: Achievements, Challenges and Perspectives
Cristina de Castro Spadari, Fernanda Wirth and Kelly Ishida
Department of Microbiology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, Brazil

Chapter 18. Trehalose Biosynthesis: Neutralizing Fungal Menace by Attacking Its Achilles Heel
Rayne S. S. Magalhães, Renata M. dos Santos and Elis C. A. Eleutherio
Institute of Chemistry, Federal University of Rio de Janeiro (UFRJ), Rio de Janeiro,Brazil

Index