Table of Contents
Table of Contents
Dedication
Preface
Chapter 1. Th17 Cells in Health
(Tsvetelina Velikova, MD, PhD, Clinical Immunology, University Hospital Lozenetz, Sofia University, Sofia, Bulgaria)
Chapter 2. The Role of Th17 Cells in Osteoclastogenesis and Rheumatoid Arthritis
(Yuki Nanke, MD, PhD, and Shigeru Kotake, MD, PhD, Institute of Rheumatology, Tokyo Women’s Medical University, Tokyo, Japan, and others)
Chapter 3. Phenotypic and Functional Heterogeneity of Th17 Cells in Systemic Sclerosis
(Rositsa V. Karalilova, MD, PhD, Department of Internal Diseases, Medical University of Plovdiv, University Hospital “Kaspela”, Clinic of Rheumatology, Plovdiv, Bulgaria)
Chapter 4. The Role of Th17 Cells in Spondyloarthritis
(Yuki Nanke, MD, PhD, and Shigeru Kotake, MD, PhD, Institute of Rheumatology, Tokyo Women’s Medical University, Tokyo, Japan)
Chapter 5. Allergic Rhinitis, IL-17 and the Concept of a Common Respiratory Pathway
(Kremena Naydenova, MD, Tsvetelina Velikova, MD, PhD, and Vasil Dimitrov, MD, PhD, Clinical Center of Allergology, University Hospital Alexandrovska, Sofia, Bulgaria, and others)
Chapter 6. Th17 Cells in Childhood Asthma
(Snezhina Lazova, MD, PhD, Guergana Petrova, MD, PhD, and Tsvetelina Velikova, MD, PhD, Pediatric Department, University Hospital “N. I. Pirogov”, Sofia, Bulgaria, and others)
Chapter 7. Th17 Cells and Cystic Fibrosis
(Guergana Petrova, MD, PhD, Snezhina Lazova, MD, PhD, and Tsvetelina Velikova, MD, PhD, Pediatric Clinic, University Hospital Alexandrovska, Medical University of Sofia, Sofia, Bulgaria, and others)
Chapter 8. Multiple Sclerosis: Th17 Cells in Immunopathogenesis and Therapy
(Marina Ivanova, MD, Ivan Milanov, MD, PhD, Ekaterina Krasimirova, MD, PhD, Dobroslav Kyurkchiev, MD, PhD, and Tsvetelina Velikova, MD, PhD, Clinic of Neurology, University Hospital of Neurology and Psychiatry “St. Naum”, Sofia, Bulgaria, and others)
Chapter 9. Inflammatory Bowel Disease in Children and Adolescents: Th17 Cells and Other Players
(Rayna R. Shentova-Eneva, MD, PhD, Department of Gastroenterology and Hepatology, University Children’s Hospital, Sofia, Bulgaria, and others)
Chapter 10. Th17/Tregs Cells in Patients with Ulcerative Colitis during Anti-TNFα Therapy
(Tsvetelina Velikova, MD, PhD, Ekaterina Ivanova-Todorova, MD, PhD, Zoya Spasova, MD, PhD, Maria Petkova, MD, Ekaterina Krasimirova, MD, PhD, Kalina Tumangelova-Yuzeir, PhD, Georgi Vasilev, MD, Lyudmila Mateva, MD, PhD, Dobroslav Kyurkchiev, MD, PhD, Laboratory of Clinical Immunology, University Hospital “St. Ivan Rilski”, Department of Clinical Immunology, Medical University of Sofia, Sofia, Bulgaria, and others)
Chapter 11. Th17 Cells Involvement in Celiac Disease
(Gergana Taneva, MD, and Tsvetelina Velikova, MD, PhD, Sveta Sofia Hospital, Bulgaria, Sofia, Bulgaria)
Chapter 12. Th17 Cells and Other Pathologies
(Tsvetelina Velikova, MD, PhD, Clinical Immunology, University Hospital Lozenetz, Medical Faculty, Sofia University, Sofia, Bulgaria)
Chapter 13. The Controversial Interaction between Th17 and T Regulatory Cells in Autoimmunity
(Tsvetelina Velikova, MD, PhD, Clinical Immunology, University Hospital Lozenetz, Medical faculty, Sofia University, Sofia, Bulgaria)
Index
Reviews
“In the last years much attention has focused on the essential role of Th17 cells in human health and protective immunity, but also in a wide spectrum of pathological processes, such as chronic inflammation, autoimmunity, allergy, and carcinogenesis. Th17 cells have been demonstrated to be pathogenic in several chronic inflammatory, immune-mediated disorders in the fields of rheumatology, dermatology, gastroenterology, neurology, etc. In this book the reader will find a comprehensive overview of the role of Th17 and Il-17 in many pathologic entities such as rheumatoid arthritis, inflammatory bowel disease, celiac disease, psoriasis, multiple sclerosis, asthma, etc.” <B>- Snejina Vassileva, MD, PhD, Professor, Department: Dermatology & Veneorology, Faculty of Medicine, Institution: Medical University Sofia, Bulgaria</B>
Audience
Scientists, doctors, specialists, PhD students, postdoc fellows, residents and everyone who is interested in Th17 cells involvement in the normal processes in the organism and Th-related diseases.
Keywords
Th17 cells, IL-17, inflammation, Tregs, autoimmunity
