Table of Contents
Table of Contents
Abstract
Introduction: Rationale for Temozolomide in High–Grade Gliomas
The Current Use of Temozolomide in High–Grade Gliomas
MGMT: Mechanisms of Action
The Standard Use of TMZ
Temozolomide and Radiotherapy
New Radiotherapy Techniques in the Treatment Strategy of HGG
TMZ Concomitant with Radiation: Is There a Rationale for That?
Comparison of the Standard Temozolomide Schedule with the Alternative Ones
Anaplastic (Grade – III) Gliomas
Temozolomide – Related Toxicity
Conclusion
References
Index