Synaptic Plasticity: Cell Biology, Regulation and Role in Disease


Gale N. McMahon (Editor)
Rich G. Buckner (Editor)

Series: Neuroscience Research Progress, Neurology – Laboratory and Clinical Research Developments
BISAC: MED057000

Synaptic plasticity is the ability of the connection, or synapse, between two neurons to change in strength in response to either use or disuse of transmission over synaptic pathways. In this book, the authors present current research in the study of the cell biology, regulation and role in disease of synaptic plasticity. Topics include the involvement of zinc via crosstalk with calcium in synaptic plasticity and neurodegeneration in the hippocampus; convergent mechanisms of drug-induced and activity-dependent plasticity; neuronal calcium sensor-1 and its role in synaptic plasticity and neurological disease; Long Term Potentiation (LTP) and Long Term Depresstion (LTD) in neurological disorders; and synaptic plasticity in addiction. (Imprint: Nova Biomedical )

Table of Contents

Table of Contents


Homeostatic Synaptic Plasticity: Molecular Mechanisms and Implications in Neurological Disorders
(James P. Gilbert, Guan Wang, Heng-Ye Man, Department of Biology, Boston University, Boston, Massachusetts, USA)

Alternate Calcium-Mediated Signaling Pathways Initiate and Limit Glutamatergic Plasticity Underlying Benzodiazepine-Withdrawal Anxiety
(Elizabeth I. Tietz, Damien E. Earl, Departments of Physiology and Pharmacology and Neurosciences, University of Toledo College of Medicine, Toledo Ohio, USA)

Neuronal Calcium Sensor-1 and Synaptic Plasticity: Role in Neurological and Neuropsychiatric Disorders
(David Fleischmann, Jamie L. Weiss, William Paterson University, Department of Biology, Wayne, New Jersey, USA)

Faulty Plasticity: A Common Thread Connecting Neurological Diseases
(Daniel Montoya, Ashley Bofill, Stephen Gill, Fayetteville State University, Biopsychology Laboratory, Department of Psychology, Fayetteville, North Carolina, USA)

Synaptic Plasticity in Addiction
(Yan Dong, R. Suzanne Zukin, Program in Neuroscience, Department of Vet and Comparative Anatomy, Pharmacology and Physiology, Washington State University, Pullman, Washington, USA, and others)*

Involvement of Zinc via Crosstalk with Calcium in Synaptic Plasticity and Neurodegeneration in the Hippocampus
(Atsushi Takeda, Department of Medical Biochemistry, School of Pharmaceutical Sciences, University of Shizuoka, Japan)*


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