Substance Use Disorders in Adolescents and Young Adults: A Manual for Pediatric and Primary Care Clinicians. Second Edition

Donald E. Greydanus, MD (Editor)
Department of Pediatric and Adolescent Medicine, Western Michigan University School of Medicine, Kalamazoo, MI, USA

Gabriel Kaplan, MD (Editor)
Clinical Associate Professor of Psychiatry at Rutgers New Jersey Medical School, Newark, New Jersey and Behavioral Health Network, RWJBarnabas Health, West Orange, New Jersey

Dilip R. Patel, MD (Editor)
Department of Pediatric and Adolescent Medicine, Western Michigan University Homer Stryker MD School of Medicine, Kalamazoo, Michigan, USA

Joav Merrick, MD, MMedSci, DMSc, (Editor)
Medical Director, Health Services, Division for Intellectual and Developmental Disabilities, Ministry of Social Affairs and Social Services, Jerusalem, Israel
Division of Adolescent Medicine, KY Children’s Hospital, Department of Pediatrics, Lexington, Kentucky, USA
National Institute of Child Health and Human Development, Jerusalem, Israel
Division of Pediatrics, Hadassah Hebrew University Medical Centers, Mt Scopus Campus, Jerusalem, Israel
School of Public Health, Georgia State University, Atlanta, Georgia, USA

Series: Pediatrics, Child and Adolescent Health
BISAC: MED069000

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This updated and revised second edition on substance abuse in adolescents and young adults provides information on this global public health topic. We cover a wide variety of subjects within the paradigm of drug abuse and agree with the 21st century message of integrating substance abuse management with primary care services. The editors thank the many experts who so graciously and lambently provided their time and knowledge in these areas. The editors hope that the readers of this treatise find useful and beneficial information that will help them in their work seeking to understand and ameliorate the negative effects of these plants of paradise and of other chemicals that are part of the drug addiction pharmacopeia of the 21st century.

The science of this field continues to evolve and this edition looks at a wide variety of concepts in this regard—-including neurobiology, genetics, the role of the primary care clinicians, the US opioid epidemic, and psychosocial management. Specific drugs of abuse include tobacco, cannabis, alcohol, opioids, prescription drugs, illicit stimulant drug abuse, hallucinogens, and date rape drugs. We also look at concepts related to prenatal drug exposure, substance abuse in adolescent females, co-occurring substance use with psychiatric disorders, prescription stimulant abuse in college students, and performance enhancing drugs in sports. We conclude with a consideration of new drugs of abuse in the 21st century, the societal burden of substance abuse, and the pros as well as cons of drug legalization.
(Imprint: Nova Medicine and Health)

Dedication

Foreword

Preface

Chapter 1. Neurobiology of Substance Use Disorders
(Ahsan Nazeer, MD, Nehdia Hashemi, MD, Nazish Imran and Muhammad Waqar Azeem, MD, Department of Psychiatry, Division of Child and Adolescent Psychiatry, Sidra Medicine, Doha, Qatar, and others)

Chapter 2. Genetics and Substance Use Disorders
(Helga V Toriello, PhD, College of Human Medicine, Michigan State University, Grand Rapids, Michigan, US)

Chapter 3. The Role of the Pediatrician and Primary Care Clinician
(Shannon W Simmons, MD, Ray Chih-Jui Hsiao, MD, and Christopher K Varley, MD, Department of Psychiatry and Behavioral Sciences, University of Washington School of Medicine, Seattle, Washington, US)

Chapter 4. The Current US Opioid Epidemic: Historical Perspective and Review of Proposed Solutions
(Yonatan Benjamin Kaplan and Gabriel Kaplan, MD, Rutgers New Jersey Medical School, Newark, New Jersey, and Behavioral Health Network, RWJBarnabas Health, West Orange, New Jersey)

Chapter 5. Psychosocial Treatments for Substance Use Disorders
(Muhammad Ather, MRCPsych, Nehdia Hashemi, MD, Ahsan Nazeer, MD, and Muhammad Waqar Azeem, MD, Department of Psychiatry, Sidra Medicine, Doha, Qatar, and others)

Chapter 6. General Pharmacotherapy Principles
(Gabriel Kaplan, MD, and Aaron Damian Kaplan, Rutgers New Jersey Medical School, Newark, New Jersey, US)

Chapter 7. Use of Pharmacologic Agents for Smoking Cessation
(Dilip R. Patel, MD, Danielle Hirsch, MD, and Kimberly Wells, Department of Pediatric and Adolescent Medicine, Western Michigan University Homer Stryker MD School of Medicine, Kalamazoo, Michigan, US)

Chapter 8. Cannabis: Current Concepts and Conundrums
(Donald E. Greydanus, MD, DrHC, Karen Randall, MD, and Maria Demma Cabral, MD, Department of Pediatric and Adolescent Medicine, Western Michigan University Homer Stryker MD School of Medicine, Kalamazoo, Michigan, US, and others)

Chapter 9. Primary Care Management of Alcohol Use and Misuse of Adolescents and Young Adults
(Angela Nash, PhD, and Oscar G Bukstein, MD, The University of Texas Health Science Center, Houston, Texas, The University of Texas, Houston, Texas and Boston Children’s Hospital, Harvard Medical School, Boston, Massachusetts, US)

Chapter 10. Opioids and Prescription Drugs
(Joseph L Calles, Jr, MD, Department of Psychiatry, Western Michigan University Homer Stryker MD School of Medicine, Kalamazoo, Michigan, US)

Chapter 11. Illicit Stimulant Use Disorders in Adolescents and Young Adults
(Marc S. Lener, MD, Sarah A. R. Anderson-Burnett, MD, PhD, Abigail R Cohen, MD, and Iliyan Ivanov, MD, Singula Institute, NY, US, and others)

Chapter 12. Hallucinogens and Date Rape Drugs
(Maria Demma Cabral, MD, Colleen Dodich, MD, and Monika Siedlarz, MD, Department of Pediatric and Adolescent Medicine, Western Michigan University School of Medicine, Kalamazoo, Michigan, US)

Chapter 13. Prenatal Drug Exposure: Maternal/Fetal Issues
(Colleen Dodich, MD, Shalin Patel, MD, Amanda Williams, MD, Arushi Tripathy and Marisha G Agana, MD, Department of Pediatric and Adolescent Medicine, Western Michigan University Homer Stryker MD School of Medicine, Kalamazoo, Michigan, US)

Chapter 14. It Is Not the Same: Issues in the Diagnosis and Treatment of Substance Abuse in Adolescent Girls
(Ruqiya Shama Tareen, MD, and Kinza Tareen, MD, Department of Psychiatry, Western Michigan University School of Medicine, Kalamazoo, Michigan and Cleveland Clinic Center for Behavioral Health, Cleveland, Ohio, US)

Chapter 15. Co-Occurring Substance Use and Psychiatric Disorders in Adolescents and Young Adults: Clinical Guidelines for Diagnosis and Treatment
(Brieana M. Rowles Marino, Aaron Ellington, PhD, Andrew Tarr, John L Hertzer, MD, Robert L. Findling, MD, and Christopher J. Hammond, MD, PhD, Department of Psychiatry and Behavioral Sciences, Johns Hopkins University, Baltimore, Maryland, US, and others)

Chapter 16. Prescription Stimulant and Other Substance Abuse in College Students
(Abigail Cohen, MD, Brandon Johnson, MD and Jeffrey H Newcorn, MD, Icahn School of Medicine at Mount Sinai, New York, US)

Chapter 17. Use of Performance Enhancing Agents by Young Athletes
(Maria Demma Cabral, MD, Dilip R. Patel MD and Donald E. Greydanus MD, DrHC, Department of Pediatric and Adolescent Medicine, Western Michigan University, Homer Stryker MD School of Medicine, Kalamazoo, Michigan, US)

Chapter 18. New Drugs of Abuse in the 21st Century
(Joseph L. Calles, Jr, MD, Department of Psychiatry, Western Michigan University Homer Stryker MD School of Medicine, Kalamazoo, Michigan, US)

Chapter 19. Estimating the Societal Burden of Substance Abuse: Advantages and Limitations of Current Methodologies
(Jonathan P. Caulkins, PhD, Anna Kasunic, and Michael A. C. Lee, Carnegie Mellon University, Pittsburgh, Pennsylvania, US)

Chapter 20. The Pros and Cons of Legalization
(Jonathan P. Caulkins, PhD, Anna Kasunic, MS, Mark Kleiman, PhD, and Michael AC Lee, Carnegie Mellon University, Pittsburgh, Pensylvania and New York University, New York, US)

About the Editors

Index

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