Stress and Developmental Programming of Health and Disease: Beyond Phenomenology

Lubo Zhang and Lawrence D. Longo (Editors)
Center for Perinatal Biology, Department of Basic Sciences, Loma Linda University School of Medicine, CA, US

Series: Public Health in the 21st Century
BISAC: HEA010000

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$470.00

Volume 10

Issue 1

Volume 2

Volume 3

Special issue: Resilience in breaking the cycle of children’s environmental health disparities
Edited by I Leslie Rubin, Robert J Geller, Abby Mutic, Benjamin A Gitterman, Nathan Mutic, Wayne Garfinkel, Claire D Coles, Kurt Martinuzzi, and Joav Merrick

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One of the most provocative recent findings in modern medicine is that perinatal stress may have a subtle or drastic impact on tissue/organ ontogeny, structure, and function, altering the vulnerability or resiliency to challenges and diseases later in life. A wealth of evidence indicates that stress and adverse environmental milieu during early development is closely associated with increased risks of the genesis of hypertension, coronary artery disease, insulin resistance, type 2 diabetes, central obesity, hyperlipidemia, and other neurobehavioral, neuropsychological and neuropsychiatric disorders in adulthood.

The concept of ‘‘Developmental Programming of Health and Disease’’ or ‘‘Fetal Origins of Adult Disease’’ has been developed to elucidate the links between stress, early development, and risks of disease later in life. Stress is an internal response to stimuli or pressures that challenge or disrupt an organism’s homeostasis in a changing environment. Adverse environmental signals that influence the development cause fetal stress. Such adverse signals can be transmitted from the mother to the fetus, impacting specific vulnerable tissues in their sensitive developmental stage, modulating normal development trajectory, remodeling their structure and function and reprogramming the resiliency or susceptibility to diseases in postnatal life. Such programming may be determined by multiple factors including gestational age, duration and mode of exposure and nature of the stressor, and these processes are tissue/organ specific. Genetic traits, epigenetic modifications and central stress mediators such as dopamine, glucocorticoids, and other transmitters may underpin such phenotypic plasticity.

This volume provides broad and up-to-date information in the recent advancement of our knowledge in the basic science of Developmental Programming of Health and Disease. Each Chapter is written by leading experts in the field, providing the highest academic level for readers including basic, clinical, and translational scientists, pediatricians, maternal-fetal medicine specialists, physiologists, environmental biologists, biostatisticians, sociologists, behavioral scientists, health economists, health informatics experts, geneticists, microbiologists, epidemiologists, medical students, university undergraduate students, and graduate students. (Imprint: Nova Biomedical)

Preface

Chapter 1 - Developmental Origins of Health and Disease – The Past and the Future (pp. 1-12)
Peter D. Gluckman and Tatjana Buklijas (Liggins Institute, The University of Auckland, New Zealand)

Chapter 2 - Programming and the Barker Hypothesis (pp. 13-86)
Kent Thornburg, Andrew J. Patterson and Lubo Zhang (Oregon Health Sciences University, Department of Medicine, Knight Cardiovascular Institute and Moore Institute for Nutrition and Wellness, Portland, OR, US and others)

Chapter 3 - Stress and Programming of Metabolic Disease (pp. 87-130)
Song Zhang, Shervi Lie, Lisa M. Nicholas, Leewen Rattanatray, Janna L. Morrison and I. Caroline McMillen (University of South Australia, Adelaide, and University of Newcastle, NSW, Australia)

Chapter 4 - The Stress of Chronic Hypoxia in Fetal Growth Restriction: Some Physiological Considerations (pp. 131-168)
Lawrence D. Longo and Ravi Goyal (Center for Perinatal Biology, Loma Linda University, School of Medicine, Loma Linda, CA, US)

Chapter 5 - Fetal Stress and Growth Restriction at High Altitude (pp. 169-238)
Lawrence D. Longo and Ravi Goyal (Center for Perinatal Biology, Loma Linda University, School of Medicine, Loma Linda, CA, US)

Chapter 6 - The Developing Brain: What is the Role of Antenatal Stress-Mediated Epigenetics? (pp. 239-340)
Lawrence D. Longo, Lubo Zhang and Ravi Goyal (Center for Perinatal Biology, Loma Linda University, School of Medicine, Loma Linda, CA, US)

Chapter 7 - Maternal Cardiovascular Adaptation and Uterine Circulation: Physiology and Pathophysiology (pp. 241-374)
Ronald R. Magness and Stephen P. Ford (Departments of Ob/Gyn, Departments of Pediatrics, and Animal Sciences, University of Wisconsin, Madison, WI and others)

Chapter 8 - The Role of the Placenta in Fetal Programming (pp. 373-386)
John R. G. Challis, Kent Thornburg and Felice Petraglia (University of Toronto, Dept of Obstetrics and Gynecology and Physiology, Toronto, Ontario; Simon Fraser University, Faculty of Health Sciences, Vancouver BC; and Dept of Obstetrics and Gynaecology, University of Western Australia, Perth, WA, US and others)

Chapter 9 - Stress and Maternal Response: Preeclampsia and Its Impact on Offspring Health (pp. 387-426)
Nicholas Parchim, Takayuki Iriyama, Olaide Ashimi and Yang Xia (Department of Biochemistry and Molecular Biology, The University of Texas - Houston Medical School, Houston; Department of Obstetrics & Gynecology and Reproductive Sciences, The University of Texas - Houston Medical School, Houston, and Graduate School of Biomedical Sciences, The University of Texas, Houston, TX, US)

Chapter 10 - Stress and the HPA Axis Response: The Ovine Model of Developmental Programming (pp. 427-462)
Dean A. Myers and Charles A. Ducsay (Dept. of Obstetrics and Gynecology, University of Oklahoma Health Sciences Center, Oklahoma City, OK, US and others)

Chapter 11 - Increased Central and Peripheral Glucocorticoid Synthesis Act As an Orchestrator of Developmental Programming (pp. 463-486)
Elena Zambrano, Nuermaimaiti Tuersunjiang, Nathan M. Long, Chunming Guo, Kang Sun, Laura A. Cox, Stephen P. Ford, Peter W. Nathanielsz and Cun Li (Instituto Nacional de la Nutricion, Mexico and others)

Chapter 12 - Early Life Stress and Predisposition to Cardiovascular Disease (pp. 487-508)
D. A. Giussani and M. A. Hanson (Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, and Human Development and Health, Institute of Developmental Sciences, Faculty of Medicine, University of Southampton, and National Institute of Health Research Nutrition Biomedical Research Centre, University Hospital Southampton, UK)
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Chapter 13 - Stress and Preterm Birth (pp. 509-540)
Inge Christiaens, David M. Olson and Gerlinde A. Metz (Obstetrics and Gynaecology, Newcastle University, Newcastle upon Tyne, UK and others)
Free Download Available

Chapter 14 - Sex Dimorphism in Developmental Programming of Health and Disease (pp. 541-558)
Kunju Sathishkumar and Chandra Yallampalli (Department of Obstetrics & Gynecology, The University of Texas Medical Branch, Galveston, and Department of Obstetrics and Gynecology, Baylor College of Medicine, Houston, TX, US)

Chapter 15 - Epigenetic Mechanisms in Developmental Programming of Health and Disease (pp. 559-600)
Fuxia Xiong, Lawrence D. Longo and Lubo Zhang (Center for Perinatal Biology, Loma Linda University, School of Medicine, Loma Linda, CA, US)

Chapter 16 - Stress, the Immune System and Cancer (pp. 601-632)
Vonetta M. Williams and Penelope Duerksen-Hughes (Department of Basic Sciences, Loma Linda University School of Medicine, Loma Linda, CA, US)

Chapter 17 - Developmental Programming of Telomere Biology: Role of Stress and Stress Biology (pp. 631-650)
Sonja Entringer and Pathik Wadhwa (Departments of Pediatrics, Obstetrics & Gynecology, Epidemiology, and Psychiatry & Human Behavior, University of California, Irvine, CA, US and others)

Chapter 18 - Cranial Compression Ischemic Encephalopathy: Fetal Neurological Injury Related to the Mechanical Forces of Labor and Delivery (pp. 651-688)
Barry S. Schifrin, Pierre Deymier and Wayne R. Cohen (Department of Obstetrics and Gynecology, University of Southern California School of Medicine, Los Angeles, CA, US and others)

Index

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