Stem Cells Origins of Cytokine Interactions


Prasad S. Koka (Editor)
Chief Scientific Director and Professor of DiponEd Institute of Regenerative Medicine Merisis Therapeutics – DiponEd BioIntelligence, Bangalore, India

Series: Stem Cells – Laboratory and Clinical Research
BISAC: MED107000

CD34+ pluripotent hematopoietic stem cells (HSCs) are generally involved in all aspects of the human system as well as in the stem cell therapeutic strategies, as in bone marrow transplantation (BMT). This book deals with several original research articles on HSC proliferation and containment. Lineage directed differentiation of HSCs and use of easily available herbal extracts for greatly increased proliferation into erythrocytes to treat thrombocytopenia are herein reported.

HSCs respond to the growth factors and the herbal medicine is a welcome substitute with lack of known side effects for treatment purposes. However molecular mechanisms as in signal transduction are more easily deciphered than those derived from the herbs which may well be taken up for future studies. Mutations in the signal transduction genes such as JAK-2 have been shown to cause dysregulation of the CD34+ cell differentiation causing erythrocytosis, which is the reverse of thrombocytopenia, both of which are undesirable clinical consequences! Erythrocytes have been shown to date back to ancient tissues from the fossils.
(Imprint: Nova Medicine and Health)



Table of Contents

Chapter 1. Stem Cells Origins of Cytokine Interactions
(Prasad Koka)

Chapter 2. Follicular Transection Rates in Follicular Unit Extraction Method
(Sandeep Mahapatra, Vignesh Subramanian, Rani James, Kaushik D. Deb, and Prasad S. Koka)

Chapter 3. Effect of Growth Hormone–Releasing Hormone and IGF-1 on Human Placenta-Derived Mesenchymal Stem Cells’ Proliferation and Differentiation
(Avinash Kharat, Usha Padmanabhan, and S. V. Gadre)

Chapter 4. Staining Methods to Distinguish between Fungi and Erythrocytes in Ancient Tissue Histology
(Inger Birgitta Sundell and Teddi J. Setzer)

Chapter 5. Potential Origins of Cancer Stem Cells in the Disease Evolution and Etiology
(Prasad S. Koka, Inger Birgitta Sundell, Usha Padmanabhan, Boris Minev, Teddi J. Setzer, and Abhay Chowdhary)

Chapter 6. Impact of Short-Term Residential Yoga-Based Lifestyle Intervention on Cognitive Function in Hypertensive Patients
(Kashinath G. Metri, Balaram Pradhan, and H. R. Nagendra)

Chapter 7. Hypoxia Decreases Osteogenic Differentiation Potential but Enhances Vasculogenic Differentiation Potential of Human Adipose Stem Cells on Biphasic Calcium Phosphate Scaffolds in Fibrin Gels
(Fransisca A. S. van Esterik, Jolanda M. A. Hogervorst, Pieter Koolwijk, and Jenneke Klein-Nulend)

Chapter 8. The Culture Medium Conditioned by Adipose Tissue Is Able to Regulate the lncRNA HOTAIR, HOXC11, HOXC12, Osx and SATB2 Gene Expression in MSCs during Osteoblasts’ Differentiation
(P. Piombino, F. Riccitiello, L. Califano, S. Rengo, G. Spagnuolo, and A. Procino)

Chapter 9. In Vitro Differentiation and Characterization of Human Hematopoietic CD34+ Stem Cells into Erythrocytes
(Pasupuleti Santhosh Kumar, Chodimella Chandrasekhar, Lokanathan Srikanth, Manne Mudhu Sunitha, and Potukuchi Venkata Gurunadha Krishna Sarma)

Chapter 10. A Retrospective Study of JAK-2 Mutations, Endogenous Erythroid Colony Formation Assay in Absolute Erythrocytosis Patients in a Tertiary Care Centre, South India
(Chandra Sekhar Chodimella, Pasupuleti Santhosh Kumar, Marthyaya Sumanth Kumar, and Potukuchi Venkata Gurunadha Krishna Sarma)

Chapter 11. Multiple Sclerosis: It Is Our Turn to Attack
(Mohamed S. A. Mohamed)

Chapter 12. Impact of the Fibroblast Morphogenetic Field Information on Human Healthy and Tumor Cell Lines In Vitro
(Dušan M. Marić, Zoran Milankov, Vesna V. Kojić, Dimitar S. Jakimov, Dzihan Abazovic, Dušica L. Marić, and Himanshu Bansal)

Chapter 13. The lncRNA HOTAIR Was Regulated by Polyacrylic Acid Resins in Human Gingival Fibroblasts
(J. Syed, G. Spagnuolo, and A. Procino)

Chapter 14. A Concept of Inducing Innate Regeneration through Cell-Free Regenerative Medicine: A Possible Therapeutic Approach for the Ischemic Cerebrovascular Insult
(Jyothi Navada Suryanarayana and Prasad S. Koka)

Chapter 15. Effects of Integrated Approach of Yoga Therapy (IAYT) on Cardiac Variables and Mental Health in Hypertensive Patients with Elevated Anxiety and Depression
(Kashinath G. Metri, Balaram Pradhan, and H. R. Nagendra)

Chapter 16. Stem Cell Genes Synergism: Elucidation of the Mechanistic Basis of Response Induced by Cytokine Combination (IL-3, FLT-3, and SCF)
(Swati Sharma, Gurudutta U. Gangenahalli, and Upma Singh)

Chapter 17. Effect of Culture Conditions on Colony-Forming Ability of Stem Cells from Human Exfoliated Deciduous Teeth
(Chareerut Phruksaniyom, Thanasup Gonmanee, Kutkao Vongsavan, Taweepong Arayapisit, Petcharat Kraivaphan, and Hathaitip Sritanaudomchai)

Chapter 18. In Vitro Proliferation of Human Haematopoietic Stem Cells by Andrographis paniculata (Burm.f.) Nees Extracts
(Thiruvengadasamy Kannan, Manne Mudhu Sunitha, Lokanathan Srikanth, Pasupuleti Santhosh Kumar, Chodimella Chandrasekhar, and Potukuchi Venkata Gurunadha Krishna Sarma)

Chapter 19. Intrinsic vs. Extrinsic Regulatory Mechanisms of Lung Stem Cell Biology and Behavior
(Ahmed H.K. El-Hashash)

Chapter 20. Quality Management in the Manufacture of Stem-Cell-Based Products
(Chandra Viswanathan, Sushilkumar Ramdasi, Rohit Kulkarni, and Abhijit Bopardikar)

Additional information