Skin Aging and Photoaging: Physiology, Clinical Aspects and Emerging Therapies


Emanuel Graham (Editor)

Series: Dermatology – Laboratory and Clinical Research
BISAC: MED017000

Skin aging is the result of two distinct, biological processes which may occur concurrently: extrinsic and intrinsic aging. The first chapter of this book focuses on the anti-skin aging effects of natural products, such as polyphenols and terpenes using topical application and oral administration. Future prospects for this field of research will focus on natural products combined with molecular techniques to help maximize the desired anti-skin aging benefits. The second chapter provides a brief review of skin characteristics, skin aging mechanisms and dermal applications.

The next chapter of the book reviews the types of pollution and external aggression that skin is exposed to and reviews recently published studies that report that cumulative exposure to the five daily environmental aggressors (pollution, sun, cold, heat and wind) increase this skin damage. The remaining chapters review the role of inflammation in regulation of skin aging; the relevant methods, the physiological structure and function of the Stratum Corneum, as well as the effects of intrinsic and extrinsic aging on these parameters; the physiology of skin photoaging and the emerging therapies for combating photoaging and photocarcingenesis; and the biological effects and the latest findings on the role of macrophage migration inhibitory factors (MIF) in photoaging following UV exposure.
(Imprint: Nova Biomedical)

Table of Contents

Table of Contents


Chapter One
An Insight into Anti-Skin Aging effects of Natural Products: Topical Application and Oral Administration
(Bin Du, Fengmei Zhu, and Baojun Xu, Beijing Normal University-Hong Kong Baptist University United International College, Zhuhai, Guangdong,
China, and others)

Chapter Two
Equol: A Botanical Active Ingredient for Human Skin Anti-aging
(Edwin D. Lephart, Department of Physiology and Developmental Biology,
The Neuroscience Center, College of Life Sciences, Brigham Young University, Provo, Utah, USA)

Chapter Three
New Insights on the Role of Pollution in Regulation of Skin Physiology and Aging
(Simarna Kaur, Michelle Garay, Marisa Dufort and Michael D. Southall, Johnson & Johnson Skin Research Center, CPPW, a Division of Johnson & Johnson Consumer Companies, Inc. Skillman, New Jersey, USA)

Chapter Four
New Insights on the Role of Inflammation in Regulation of Skin Aging
(Ali Fassih, Anne-Sophie Brillouet, Dianne Rossetti, Simarna Kaur and Michael D. Southall, Johnson and Johnson Consumer Companies, Inc.,
Skillman, NJ, USA)

Chapter Five
Aging Effects on the Physiology of the Stratum Corneum
(Elise Boireau-Adamezyk, Arlette Baillet-Guffroy, and Georgios N Stamatas, Université Paris Sud 11, Châtenay-Malabry, France, and others)

Chapter Six
Polyphenolic Nanobiomaterials as Emerging Therapies for Combating Physiology and Clinical Aspects of Photoaging and Photocarcinogenesis
(Neena Philips, Jovinna Chalensouk-Khaosaat, Avani Devmurrai and Hardika Patel, Fairleigh Dickinson University, Teaneck, NJ, USA)

Chapter Seven
Ultraviolet-Induced Photoaging in the Skin: The role of Inflammatory Cytokine, Macrophage Migration Inhibitory Factor
(Mati Ur Rehman, Takashi Kondo, Tadamichi Shimizu, Department of Dermatology, Department of Radiological Sciences, Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama, Sugitani, Toyama, Japan)


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