Sjögren’s Syndrome: Symptoms, Treatment Options and Potential Health Complications


Eduardo M. Hernandez (Editor)

Series: Immunology and Immune System Disorders
BISAC: MED022000

Sjögren’s syndrome (SS) is a multi-system exocrinopathy. Its etiology remains unknown and it has an autoimmune pathogenesis. Although SS has been reported in young children and men, it is more frequent in middle-aged women. SS may occur alone, defined as primary SS, or in association with another autoimmune disease, defined as secondary SS. SS has a wide variety of glandular and extra-glandular manifestations affecting almost every organ.

Despite its apparently inoffensive initial manifestations, SS can become a disabling and potentially life-threatening disease. This book discusses Sjögren’s syndrome in detail, and provides further insight on topics that include the clinical manifestation and management of SS; the symptoms and diagnosis; health related quality of life in patients with SS; the involvement SS has in the central nervous system; and new aspects of mechanism of salivary glans dysfunctions in SS. (Imprint: Nova Biomedical )

Table of Contents

Table of Contents


Chapter 1 – Omega 3 Fatty Acids and Primary Sjogren‟s Syndrome: Overview and Exploratory Investigation (pp. 1-12)
J. Wu, B. Nazir, D. A. Brand and S. E. Carsons (Department of Medicine, Office of Health Outcomes Research, Winthrop-University Hospital, Mineola, NY, USA, and others)

Chapter 2 – An Overview of the Clinical Manifestations and Management of Primary Sjögren‟s Syndrome (pp. 13-56)
Josephine Vila, Rebecca Batten and Wan-Fai Ng (Newcastle upon Tyne Hospitals NHS Foundation Trust, UK, and others)

Chapter 3 – Sjögren‟s Syndrome Symptoms and Diagnosis (pp. 57-82)
Antonio Bascones-Martínez, Elena Ruiz-Capillas, D.D.S. Cristina Bascones-Ilundain, D.D.S., Ph.D. and Virginia Garcia Garcia, D.D.S., Ph.D. (Oral Medicine and Periodontology, Faculty of Dentistry, Complutense University of Madrid, Madrid, Spain, and others)

Chapter 4 – Health-Related Quality of Life and Sexual Health in Patients with Sjögren‟s Syndrome and with Not- Sjögren‟s Sicca Syndrome (pp. 83-102)
Angela Del Rosso, Susanna Maddali Bongi and Svetlana Mikhaylova (Department of Experimental and Clinical Medicine, Division of Medicine, University of Florence, Italy)

Chapter 5 – Involvement of the Central Nervous System in Sjögren‟s Syndrome (pp. 103-124)
Sandra Gofinet Pasoto, M.D., Ph.D. and Tamyris de Sousa Bocate (Rheumatology Division, University of São Paulo, São Paulo, Brazil)

Chapter 6 – New Aspects of Mechanism of Salivary Gland Dysfunction in Sjögren‟s Syndrome (pp. 125-158)
Takashi Fujimoto, Kiyomi Yoshimoto, Takanori Fujimura, Maiko Takeda, Asako Itaya-Hironaka and Shin Takasawa (The Center for Rheumatic Diseases, Departments of General Medicine, Biochemistry, Nara Medical University, Kashihara, Japan)


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