Signaling, Gene Regulation and Cancer


Shree Ram Singh (Editor)
National Cancer Institute, Frederick, MD

Manoj K. Mishra (Editor)
Alabama State University, Montgomery, AL

Series: Cancer Etiology, Diagnosis and Treatments
BISAC: MED062000

Although there have been tremendous progress in cancer research and treatment, the mortality caused by this disease is still very high. Cancer is the leading cause of death worldwide and second leading cause of death in the United States of America. The book covers topics including the role of various signaling pathway in development, regulation of cell fate, tumor angiogenesis, duodenal neoplasias, breast, colorectal and prostate cancer, cancer development and progression, microRNA in cancer and epigenetic regulation of cancer. This book will provide valuable information for cell biologists, geneticists, cancer biologists, clinicians, and students involved in various aspects of cell signaling, regulation of genes and cancer. (Imprint: Nova Biomedical )

Table of Contents

Table of Contents



1. Cell Death and Survival Signaling in Cancer Therapy
(Simone Fulda)

2. C4ST-1 and Chondroitin Sulfate in Growth Factor Signaling, Development, and Cancer
(Catherine M. Willis, Robert D. Prinz, and Michael Kl¨¹ppel)

3. NFAT Signaling and Transcription in Cancer Development and Progression
(Sandra Baumgart, Elisabeth Glesel, Shiv K Singh, Garima Singh, Nai-Ming Chen, Kristina Reutlinger and Volker Ellenrieder)

4. JAK/STAT Signaling in Cell Fate and Tumorigenesis
(Shree Ram Singh and Manoj K. Mishra)

5. Role of TGF ¦Â and Regulatory T Cells in Prostate Cancer
(Manoj K. Mishra, Erdal Erglou, Sapna Jain, Shree R Singh, Udai, P. Singh, Renu Bhatt, Shree Ram Singh)

6. Signaling Pathways, Gene Regulation and Duodenal Neoplasias
(Carlos A. Rubio)
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7. Targeting Cancer Cells in Head and Neck Tumors
(C. Bianchini, A. Ciorba, S. Pelucchi S., A. Pastore)

8. Akt in Human Colorectal Cancer
(Kumar S. Bishnupuri*, Satheesh K. Sainathan)

9. Dysregulation of Cellular Signaling in Colorectal Cancer
(William KK Wu, Jun Yu)

10. Systems Biology of Nuclear Hormone Signaling and Gene Regulation
(Mei Hui Liu & Edwin Cheung)

11. Targeting Breast Cancer
(Ashok Jain)

12. Notch Signaling Regulates Cancer Stem Cells and Tumor Angiogenesis
(Rashmi K. Ambasta, S.Esther Priyadharshini, Archita Sharma and Pravir Kumar)

13. Cell Cycle Deregulation in Neuro-Oncogenesis: A Fatal Journey by Cells
(Pravir Kumar Rashmi, K. Ambasta, M. Sonia Angeline Inbakumari and Mandar Bhattacharya)

14. Combinatorial Effect of Heat Shock Proteins and Ubiquitin Proteasome System in Neuro-Oncology
(Pravir Kumar, Rashmi K. Ambasta, Aditi Sarkar , Abhidha Kohli and Kushi Anand)

15. Biological Functions of IL-4/IL-13, Signaling Cascades and Implication in Growth and Development of Tumor
(Praveen Deepak, Arbind Acharya)

16. Potential Molecular Targets in Ovarian Cancer
(Indrajit Chowdhury, Roland Matthews and Winston E. Thompson)

17. MicroRNAs and their Involvement in Cancer
(Kartz E. Bibb)

18. Histone Posttranslational Modifications and Cancer Epigenomics
(Chhavi Chauhan)

19. Epigenetic Regulation of Cancer
(Rakesh Kumar Singh, Rohit Seth and Akash Gunjan)

20. An Overview of Cell Cycle Regulation and Tumor Viruses
(Shuntele N. Burns)

21. Biodegradable Polymeric Nano-Biomaterials for Cancer Therapeutic Applications
(Vinoy Thomas, Bini Mathew, Derrick R. Dean, Elijah Nyairo)

22. Cisplatin in Cancer Management ¨C New Approaches for Bypassing Nephrotoxicity
(Rohit Seth, Rakesh Kumar Singh and Alka Seth)


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