Ruthenium Complexes as Photosensitizers: New Possibilities in Photodynamic Therapy

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Shawn Swavey
University of Dayton, Dayton, Ohio, USA

Series: Chemistry Research and Applications
BISAC: SCI013000

From anticancer drugs such as cisplatin to imaging agents of europium and terbium, metal complexes have become an integral part of many aspects of medicine today. Photodynamic therapy (PDT) is a growing field of medicine as a treatment modality for a variety of cancers, macular degeneration, and antibacterials, to name a few. PDT utilizes photosensitizers, typically organic macrocycles, to produce the photodynamic effect; however, a growing area of study deals with new photosensitizers based on transition metal complexes. This book discusses the most recent advances in ruthenium chemistry as it relates to photodynamic therapy. (Imprint: Nova)

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Table of Contents

I. ABSTRACT

II. INTRODUCTION

III. MONOMETALLIC RUTHENIUM COMPLEXES

IV. DNA INTERACTIONS WITH MULTI-METALLIC RUTHENIUM COMPLEXES

V. PORPHYRIN-RUTHENIUM COMPLEXES IN PDT

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