Ruthenium Complexes as Photosensitizers: New Possibilities in Photodynamic Therapy

Shawn Swavey
University of Dayton, Dayton, Ohio, USA

Series: Chemistry Research and Applications
BISAC: SCI013000

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Volume 10

Issue 1

Volume 2

Volume 3

Special issue: Resilience in breaking the cycle of children’s environmental health disparities
Edited by I Leslie Rubin, Robert J Geller, Abby Mutic, Benjamin A Gitterman, Nathan Mutic, Wayne Garfinkel, Claire D Coles, Kurt Martinuzzi, and Joav Merrick

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From anticancer drugs such as cisplatin to imaging agents of europium and terbium, metal complexes have become an integral part of many aspects of medicine today. Photodynamic therapy (PDT) is a growing field of medicine as a treatment modality for a variety of cancers, macular degeneration, and antibacterials, to name a few. PDT utilizes photosensitizers, typically organic macrocycles, to produce the photodynamic effect; however, a growing area of study deals with new photosensitizers based on transition metal complexes. This book discusses the most recent advances in ruthenium chemistry as it relates to photodynamic therapy. (Imprint: Nova)

I. ABSTRACT

II. INTRODUCTION

III. MONOMETALLIC RUTHENIUM COMPLEXES

IV. DNA INTERACTIONS WITH MULTI-METALLIC RUTHENIUM COMPLEXES

V. PORPHYRIN-RUTHENIUM COMPLEXES IN PDT

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