Rett Syndrome (RTT): From Diagnosis to Treatment


Associate Professor, Developmental Psychology,  “Giustino Fortunato” University of Benevento, Italy

Series: Health Psychology Research Focus
BISAC: MED056000

Rett syndrome, a rare genetic disease caused by mutations of the MECP2 gene, includes severe to profound developmental impairments. Communicative, intellectual, and motor disabilities are usually embedded. Children with Rett syndrome are individuals with multiple difficulties. Caregivers, families and professionals face to serious daily challenges due to clinical conditions determined by Rett syndrome. Accordingly, traditional interventions may not be adequate. Customized programs based on cognitive-behavioral approaches and assistive technology setups are highly warranted.

The current book includes the newest empirical contributions to tackle functional consequences of Rett syndrome. Sleep and pain disorders were targeted in Chapter One. A cross-disciplinary investigation to enhance active participation and constructive engagement of children with Rett syndrome was detailed in Chapter Two. The importance of functional activities was emphasized in Chapter Three. Communication guidelines to support communication skills of individuals with Rett syndrome were critically discussed in Chapter Four. The relevance of music and music therapy to promote positive participation was argued in Chapter Five. A selective review on the use of assistive technology-based programs in individuals with Rett syndrome was provided in Chapter Six. A case report to help locomotion fluency of an adolescent with Rett syndrome through the use of microswitches and contingent positive stimulation was presented in Chapter Seven.

The book was supported by illustrative examples described by the chapters’ contributors and their professional experience. Readers may find helpful insights within each edited chapter. Caregivers, families, and professionals may have a practical guide to everyday settings and environments or contexts. Clarity and readability for a large audience are undoubtedly strengths and advantages of the current volume. Although technical terminology was used throughout, both future research and practice can widely find meaningful tips and tangible suggestions to tackle daily barriers and/or obstacles in individuals with Rett syndrome and severe to profound developmental delays.

Table of Contents


Chapter 1. Occupational and Physical Therapy Management of Pain and Sleep Disorders in Children with Rett Syndrome
(Mary Swiggum & Stacey S. Caplan – Wingate University)

Chapter 2. Specialist Investigation of Motor Function and Communicative Ability in Rett Syndrome – using Engagement and Active Participation
(Lena Svedberg, Åsa-Sara Sernheim & Helena Wandin – The Swedish National Center for Rett syndrome & related disorders, Frösön, Sweden)

Chapter 3. The Significance of Doing: Activities and Rett syndrome
(Åsa-Sara Sernheim – The Swedish National Center for Rett Syndrome & Related Disorders, Frösön, Sweden)

Chapter 4. Communication Assessment in Rett Syndrome from an ICF perspective – Tools for Assessing Participation and Environmental and Personal factors
(Helena Wandin – The Swedish National Center for Rett syndrome & related disorders, Frösön, Sweden, et al.)

Chapter 5. Music and Music Therapy in Rett Syndrome from Assessment to Treatment
(Cochavit Elefant, Sophie Larsson, & Meir Lotan – School for Creative Art Therapies, University of Haifa. Israel, et al.)

Chapter 6. Assistive Technology to Improve the Quality of Life in People with Rett Syndrome: A Selective Review
(Donatella Ciarmoli & Fabrizio Stasolla – Giustino Fortunato University of Benevento, Italy)

Chapter 7. Promoting Locomotion Fluency through a Microswitch-Based Program in an Adolescent with Rett Syndrome: Contingency’s Awareness and Positive Mood
(Fabrizio Stasolla & Donatella Ciarmoli – “Giustino Fortunato” University of Benevento, Benevento, Italy)


Editor’s ORCID iD

Fabrizio Stasolla

Additional information



Publish with Nova Science Publishers

We publish over 800 titles annually by leading researchers from around the world. Submit a Book Proposal Now!