Rett Syndrome and Other Communication Disorders: Symptoms, Treatment and Prognosis

Daniel L. Kolby (Editor)

Series: Neurology – Laboratory and Clinical Research Developments
BISAC: MED107000




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Rett syndrome is a X-linked neurodevelopmental disorder that affects 1 in 10,000 females. It presents itself clinically with developmental regression at 6-18 months of age, with loss of acquired language and motor skills, leading to a complex lifelong syndrome characterised by intellectual disability; behavioural and neuropsychiatric disturbances; social withdrawal; hand stereotypies; epilepsy; autonomic dysfunction causing breathing irregularities and cardiac arrhythmias; muscle tone abnormalities leading to orthopaedic deformities such as scoliosis; and motor incoordination that causes gait disturbance and feeding difficulties which, along with a number of gastrointestinal problems, leads to growth failure and nutritional deficiencies. This book discusses symptoms, treatment and prognosis of Rett Syndrome, as well as other related communication disorders. (Imprint: Nova Biomedical)


Chapter 1 - Treating Rett Syndrome: Current Approaches and New Treatments (pp. 1-58)
D. Tropea, S. Wrigley and G. Pini (Neuropsychiatric Genetics, Trinity Centre for Health Sciences, St James Hospital, D8, Dublin, Ireland, and others)

Chapter 2 - Assistive Technology to Promote Communication, Leisure and Occupation Skills for Children with Rett Syndrome and Severe to Profound Developmental Disabilities: A Literature Overview (pp. 59-80)
Fabrizio Stasolla and Viviana Perilli (Lega del Filo d’Oro Research Center, Molfetta, Italy and Viviana Perilli, Lega del Filo d'Oro Research Center, Lesmo Italy)

Chapter 3 - Microvascular Modifications in Rett Syndrome (pp. 81-92)
G. Bianciardi, M. Acampa and M. Pastorelli (Dpt. Biotecnologie mediche, Anatomia Patologica, Università di Siena, Siena, Italy, and others)


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