Table of Contents
Table of Contents
1. INTRODUCTION
2. NUCLEAR RECEPTORS
3. INVOLVEMENT IN HEPATIC DISEASES
4. STAP/CTYOGLOBIN EXPRESSION IN HSCS
5. DEVELOPMENT (ONTOGENY AND PHYLOGENY)
6. AGEING
7. IMMUNITY AND HSCS
CONCLUSIONS
INDEX
Regulation of Vitamin A Homeostasis by the Stellate Cell (Vitamin A-Storing Cell) System
$59.00
Haruki Senoo
Akita University School of Medicine, Akita-City, Akita, Japan
Series: Nutrition and Diet Research Progress, Cell Biology Research Progress
BISAC: SCI017000
Vitamin A-storing cells in the liver exist in the space between parenchymal cells and liver sinusoidal endothelial cells of the hepatic lobule, and store 50-80% of vitamin A in the whole body as retinyl palmitate in lipid droplets in the cytoplasm. In physiological conditions, these cells play pivotal roles in the regulation of vitamin A homeostasis. In pathological conditions such as hepatic fibrosis or liver cirrhosis, hepatic stellate cells lose vitamin A, and synthesize a large amount of extracellular matrix components including collagen, proteoglycan, glycosaminoglycan, and adhesive glycoproteins. Morphology of these cells also changes from the star-shaped stellate cells to that of fibroblasts or myofibroblasts. This book discusses and presents research on vitamin A-storing cells.
(Imprint: Nova Biomedical)