Recent Avenue to Cancer Prevention

$179.00

Zsuzsanna Suba (Editor)
National Institute of Oncology, Department of Surgical and Molecular Tumor Pathology, Budapest, Hungary

Series: Cancer Etiology, Diagnosis and Treatments
BISAC: SCI055000

This work presents some recent clinical, epidemiological and experimental data on the cancer preventive effect of healthy hormonal equilibrium. Insulin resistance-associated overproduction of peptide hormones, such as growth hormone, insulin and insulin-like growth factors, interacting simply with cell membrane receptors, have a proven tumor inducing capacity. Another group of hormones, including estrogens, thyroids and vitamin D, has both genomic intranuclear and non-genomic membrane-associated receptor signaling, thus they have complex roles in all basic cellular functions. Recent results suggest that defective synthesis of these latter hormones or alterations of their signal transduction pathways may thoroughly disturb metabolic processes, reproduction and the regulation of cell proliferation.

Primary cancer prevention based on the preservation or restoration of the hormonal and metabolic equilibrium of patients may be the main program of the anticancer fight in the 21st century. Moreover, in cases with diagnosed malignancy, we should cure the ill patients instead of their tumors. After surgical tumor removal, the achievement of hormonal and metabolic equilibrium restores the natural defense mechanisms of patients, which may help to stop tumor recurrence. (Nova Biomedical) (Imprint: Nova Biomedical )

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Table of Contents

Table of Contents

Preface

Chapter 1. A long way from hyperestrogenism to estrogen deficiency as mediator of cancer risk in obesity. (Zsuzsanna Suba, National Institute of Oncology, Department of Surgical and Molecular Pathology, Budapest, Hungary)
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Chapter 2. Light exposure associated hormonal equilibrium is protective against cancer risk.
(Zsuzsanna Suba, National Institute of Oncology, Department of Surgical and Molecular Pathology, Budapest, Hungary)
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Chapter 3. Sexual dimorphism in obesity related cancer risk (Zsuzsanna Suba, National Institute of Oncology, Department of Surgical and Molecular Pathology, Budapest, Hungary)
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Chapter 4. Recovery of estrogen level in obese women is preventive against cancer. (Zsuzsanna Suba, National Institute of Oncology, Department of Surgical and Molecular Pathology, Budapest, Hungary)
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Chapter 5. Estrogen receptors are pivotal regulators of glucose uptake and energy expenditure. (Zsuzsanna Suba, National Institute of Oncology, Department of Surgical and Molecular Pathology, Budapest, Hungary)
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Chapter 6. Triple-negative breast cancer risk in women is increasing by the loss of estrogen supply or by defective estrogen signaling. (Zsuzsanna Suba, National Institute of Oncology, Department of Surgical and Molecular Pathology, Budapest, Hungary)
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Chapter 7. Role of ultraviolet-B irradiance and vitamin D in reducing risk of cancer. (William B. Grant1, Meis Moukayed2, Sunlight, Nutrition and Health Research Center, San Francisco, California, USA1, School of Arts and Sciences, American University in Dubai, Dubai, UAE2)
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Index

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