Recent Advances in Mitochondrial Medicine and Coenzyme Q10

Anna Gvozdjáková (Editor)
Comenius University in Bratislava, Bratislava, Slovakia

Germaine Cornelissen (Editor)
University of Minnesota, Medical School, Minneapolis, USA

Ram B. Singh (Editor)
Halberg Hospital and Research Institute, Moradabad, India

Series: Medicine and Biology Research Developments
BISAC: MED014000

Clear

$230.00

eBook

Digitally watermarked, DRM-free.
Immediate eBook download after purchase.

Product price
Additional options total:
Order total:

Quantity:

Details

Recent Advances in Mitochondrial Medicine and Coenzyme Q10 (eds. Anna Gvozdjáková, Germaine Cornélissen, Ram B Singh) is an updated version of a book Mitochondrial Medicine (ed. A. Gvozdjáková) published by Springer, The Netherlands, in 2008.

International contributors and world specialists in Mitochondrial Medicine and Coenzyme Q10 provide up-to-date knowledge in mitochondrial physiology, and review the role played by mitochondria in relation to diseases, diagnosies and therapies pertinent to various fields of medicine. This monograph covers topics related to mitochondrial physiology, mitochondrial sirtuins, supercomplexes, chronobiology, epigenetics, genetics, neurology, cardiology, nephrology, immunology, diabetology, oncology, and reproductive medicine. A chapter on the history of coenzyme Q10 focuses on the work of Prof. Frederick L Crane, discoverer of coenzyme Q10, who died in 2015.
Current diagnostic methods of mitochondrial disturbances are reviewed, including a new non-invasive approach using high-resolution respirometry in human blood cells.

The effectiveness of supplementary therapies of mitochondrial disturbances is examined for the case of natural antioxidants, melatonin, high protein diet, omega-3-PUFA, omega-6-PUFA, natural mineral water sources and polarized light. Targeting mitochondrial therapy involves coenzyme Q10 (ubiquinone, ubiquinol), prospective mitochondrial replacement therapy and mitochondrial transplantation.

This book is intended for general medical practitioners and specialists in various fields of medicine, including neurologists, cardiologists, geneticists, nephrologists, diabetologists, lipidologists, immunologists, oncologists, pharmacists, biochemists and nutritionists. Pre- and post-graduate education physicians, pharmacists and biochemists will also benefit from material covered in this monograph.

Preface

Chapter 1. Mitochondrial Medicine
(Anna Gvozdjáková, Rafael de Cabo, and Plácido Navas, Pharmacobiochemical Laboratory of the 3rd Department of Internal Medicine, Medical Faculty, Comenius University in Bratislava, Slovakia, and others)

Chapter 2. Mitochondrial Physiology
(Anna Gvozdjáková, Pharmacobiochemical Laboratory of the 3th Department of Internal Medicine, Mediacl Faculty, Comenius University in Bratislava, Slovakia)

Chapter 3. Mitochondrial Free Radicals and Antioxidants
(Anna Gvozdjaková, Zdeòka Ïuraèková and Ingrid Žitòanová, Pharmacobiochemical Laboratory of the 3rd Department of Internal Medicine, Medical Faculty, Comenius University in Bratislava, Slovakia)

Chapter 4. Chronobiology of Mitochondria
(Germaine Cornélissen, Anna Gvozdjáková, Cathy Lee Gierke, Lyazzat Gumarova and Linda Sackett Lundeen, Halberg Chronobiology Center, University of Minnesota, Minneapolis, MN, USA)

Chapter 5. Mitochondrial Modulation of the Epigenome and the Emergence of Cardiometabolic Diseases
(Ram B. Singh and Anna Gvozdjáková, Halberg Hospital and Research Institute, Civil Lines, Moradabad, India)

Chapter 6. Mitochondrial Diseases
(Anna Gvozdjáková and Ram B. Singh, Pharmacobiochemical Laboratory of the 3rd Department of Internal Medicine, Medical Faculty, Comenius University in Bratislava, Slovakia, and others)

Chapter 7. Mitochondrial DNA
(Diana Drobná and Peter Celec, Institute of Molecular Biomedicine, Faculty of Medicine, Comenius University in Bratislava, Bratislava, Slovakia)

Chapter 8. Mitochondrial Neurology
(Anna Gvozdjáková, Jarmila Kucharská and Boris Mravec, Pharmacobiochemical Laboratory of the 3rd Department of Internal Medicine, Medical Faculty, Comenius University in Bratislava, Slovakia, and others)

Chapter 9. Autism Spectrum Disorder and Mitochondrial Dysfunction
(Katarína Babinská, Anna Gvozdjáková, Jarmila Kucharská, Lenka Vokálová, Gabriela Repiská, Dalibor Nakládal, and Daniela Ostatníková, Institute of Physiology, Medical Faculty, Comenius University in Bratislava, Slovakia, and others)

Chapter 10. Mitochondrial Cardiology
(Anna Gvozdjáková, Jarmila Kucharská, Naranjan S. Dhalla, and Fedor Šimko, Pharmacobiochemical Laboratory of the 3th Department of Internal Medicine, Medical Faculty, Comenius University in Bratislava, Slovakia, and others)

Chapter 11. Mitochondrial Diabetology
(Jarmila Kucharská, Anna Gvozdjáková, Ram B Singh, Viliam Mojto, and Germaine Cornélissen, Pharmacobiochemical Laboratory of the 3th Department of Internal Medicine, Medical Faculty, Comenius University in Bratislava, Slovakia, and others)

Chapter 12. Mitochondrial Nephrology
(Katarína Gazdíková, and Viliam Mojto, Department of General Medicine, Medical Faculty and Institute of Nutrition, Faculty of Nursing and Professional Health Studies Slovak Medical University, Bratislava, Slovakia, and others)

Chapter 13. Mitochondrial Immunology
(Katarína Gazdíková, Department of General Medicine, Medical Faculty and Institute of Nutrition, Faculty of Nursing and Professional Health Studies, Slovak Medical University, Bratislava, Slovakia)

Chapter 14. Mitochondrial Oncology
(Patrik Palacka, 2nd Oncology Department, Medical Faculty, Comenius University in Bratislava, Slovakia)

Chapter 15. Mitochondrial Reproductive Medicine
(Anna Gvozdjáková, Jozef Dúbravický, and Ram B. Singh, Pharmacobiochemical Laboratory of the 3th Department of Internal Medicine, Medical Faculty, Comenius University in Bratislava, Slovakia)

Chapter 16. Methods for Diagnosing Mitochondrial Disturbances
(Anna Gvozdjáková, Jarmila Kucharská, Zuzana Rausová, and Anna Hlavatá, and others, Pharmacobiochemical Laboratory of the 3rd Department of Internal Medicine, Medical Faculty, Comenius University in Bratislava, Slovakia)

Chapter 17. Respirometric Analysis of Mitochondrial Function in Human Blood Cells
(Zuzana Sumbalová, Luiz F. Garcia-Souza, Beáta Veliká, Chiara Volani and Erich Gnaiger, Daniel Swarovski Research Laboratory, Department of Visceral, Transplant and Thoracic Surgery, Medical University of Innsbruck, Innsbruck, Austria, and others)

Chapter 18. Coenzyme Q10 Targeting Therapy of Mitochondrial Disturbances
(Anna Gvozdjáková, Jarmila Kucharská, Rafael de Cabo, Luca Tiano and Plácido Navas, Pharmacobiochemical Laboratory of the 3rd Department of Internal Medicine, Medical Faculty, Comenius University in Bratislava, Slovakia, and others)

Chapter 19. Targeting Mitochondria with Natural Antioxidants
(Zdeòka Ïuraèková, Branislav Trebatický, Jana Trebatická, and Jana Muchová, Institute of Medical Chemistry, Biochemistry and Clinical Biochemistry, Medical Faculty, Comenius University in Bratislava, Slovakia, and others)

Chapter 20. Mitochondrial Transplantation
(Anna Gvozdjáková and Ram B. Singh, Pharmacobiochemical Laboratory of the 3rd Department of Internal Medicine, Medical Faculty, Comenius University in Bratislava, Slovakia, and others)

Chapter 21. Melatonin as a Natural Protector of Mitochondria
(Fedor Šimko, Institute of Pathophysiology, Medical Faculty, Comenius University in Bratislava, Slovakia, and others)

Chapter 22. The Effects of a High-Protein Diet on Mitochondria
(Anna Gvozdjáková, Jarmila Kucharská, Zuzana Paduchová, Mária Kubalová, and Jana Muchová, Pharmacobiochemical Laboratory of the 3rd Department of Internal Medicine, Medical Faculty, Comenius University in Bratislava, Slovakia, and others)

Chapter 23. Omega-3-PUFA, Omega-6-PUFA and Mitochondrial Dysfunction in Relation to Remodelling
(Ram B. Singh, Anna Gvozdjáková, Jaipaul Singh, Sergey Shastun, Naranjan S. Dhalla, Daniel Pella, Ján Fedaèko, and Germaine Cornélissen, Halberg Hospital and Research Institute, Moradabad, India)

Chapter 24. Balneotherapy and the Effect of Natural Mineral Water on Mitochondrial Function
(Anna Gvozdjáková, Pharmacobiochemical Laboratory of the 3th Department of Internal Medicine, Medical Faculty, Comenius University in Bratislava, Slovakia)

Chapter 25. The Effect of Polarized Light and Coenzyme Q10 on Mitochondrial Function
(Anna Gvozdjáková and Alfonz Smola, Pharmacobiochemical Laboratory of the 3rd Department of Internal Medicine, Medical Faculty, Comenius University in Bratislava, Slovakia)

Index

This book is intended for general medical practitioners and specialists in various fields of medicine, including neurologists, cardiologists, geneticists, nephrologists, diabetologists, lipidologists, immunologists, oncologists, pharmacists, pharmacologists, biochemists and nutritionists. Pre- and post-graduate education physicians, pharmacists and biochemists will also benefit from materials covered in this monograph.

If you have any questions or comments with regards to this book, please fill out the form below. Thank you!

You have not viewed any product yet.