Recent Advancements and Applications in Dosimetry


Series: Cancer Etiology, Diagnosis, and Treatments
BISAC: MED080000

– Provides unique dosimetry for high-intensity MR-guided ultrasound treatment, gold nanoparticle-enhanced radiotherapy, photodynamic therapy, thermal imaging in Brachytherapy, MR-guided radiotherapy, proton beam treatment, and high-definition end-to-end patient-specific dose verification
– Offers clinical applications for all varieties of modern radiation detectors, and evolving dosimetry techniques including innovative calorimetry, TLD, Oone-scan film dosimetry, transmission detectors, real-time EPID dosimetry, best feasible DVH planning, 3D printing, 5D planning and delivery, as well as machine learning

This book provides a comprehensive collection of the newly emerging treatment modalities, covering high-intensity ultrasound treatment, photodynamic therapy, MR-guided treatment machines, nanoparticle-enhanced radiotherapy, and proton beam therapy. The invited expert authors cover a wide range of the latest advancements and developments in dosimetry techniques as well asnd their clinical implications, including calorimetry, radiochromic film, transmission detectors, real-time portal dosimetry, TLD, thermal imaging dosimetry, 3D dosimetry, best feasible DVH planning, 5D planning and delivery, 3D printing, as well asand machine learning in medical dosimetry. This book will bring the reader up-to-date with the state of the art in radiation dosimetry and best clinical practices using such advanced detectors.

Table of Contents

Table of Contents


Chapter 1. Dosimetry for High-Intensity Ultrasound Treatment
(Lili Chen, PhD and C-M Charlie Ma, PhD, Department of Radiation Oncology, Fox Chase Cancer Center, Philadelphia, PA, US)

Chapter 2. Monte Carlo Nanodosimetry in Gold Nanoparticle-Enhanced Radiotherapy
(James Chun Lam Chow, PhD, Radiation Medicine Program, Princess Margaret Cancer Centre, University Health Network, Toronto, ON, CA, and others)

Chapter 3. Photodynamic Therapy Explicit Dosimetry
(Yi Hong Ong, PhD, Michele M. Kim, PhD, and Timothy C. Zhu, PhD, Department of Radiation Oncology, University of Pennsylvania, PA, US)

Chapter 4. Thermal Imaging Applications in HDR Brachytherapy Dosimetry
(Xiaofeng Zhu, PhD and Dandan Zheng, PhD, Department of Radiation Medicine, Medstar Georgetown University Hospital, Washington, DC, US, and others)

Chapter 5. Proton Dosimetry, Commissioning and Applications
(Yin Zhang, PhD, Irina Vergalasova, PhD, Ning Yue, PhD, and Ke Nie, PhD, Department of Radiation Oncology, Rutgers Cancer Institute of New Jersey, New Brunswick, NJ, US)

Chapter 6. Dosimetric Impact of Magnetic Field in MRI Guided Radiotherapy
(Victoria Y. Yu, PhD, and Minsong Cao, PhD, Department of Radiation Oncology, University of California, Los Angeles, CA US)

Chapter 7. Innovations in Calorimetry
(Humza Nusrat, James Renaud, Ph.D and Arman Sarfehnia, Ph.D., Department of Physics, Ryerson University, Toronto, ON, CA, and others)

Chapter 8. One-Scan Film Dosimetry across Multimodalities of Delivery
(Maria F. Chan, PhD, Department of Medical Physics, Memorial Sloan Kettering Cancer Center, New York, NY, US)

Chapter 9. Time-Resolved Dosimetry and Quality Assurance Using Real-Time EPID Imaging
(Benjamin Zwan and Peter B. Greer, PhD, Central Coast Cancer Centre, Gosford Hospital, Gosford, NSW, Australia, and others)

Chapter 10. High-Definition 3D Dosimetry for End-To-End Patient-Specific Treatment Delivery Verification
(Marek J. Maryanski, PhD, MGS Research, Inc., Madison, CT, USA)

Chapter 11. A Priori Estimation of Best Feasible DVH in Radiotherapy Planning
(David V. Fried, PhD, and Greg Robinson, Department of Radiation Oncology, University of North Carolina at Chapel Hill, Chapel Hill, NC, US, and others)

Chapter 12. Of Mice and Men: Applications of Thermoluminescent Dosimetry
(Yvonne Dzierma, PhD, and Frank Nuesken, PhD, Department of Radiotherapy and Radiation Oncology, Saarland University Medical Center, Homburg, Germany)

Chapter 13. Design, Characteristics, and Applications of Transmission Detectors for Advanced Quality Assurance
(Taoran Li, PhD, Jennifer O’Daniel, PhD, and Q. Jackie Wu, PhD, Department of Radiation Oncology, University of Pennsylvania, Philadelphia, PA US, and others)

Chapter 14. 3D Printing Applications in Dosimetry
(Takeshi Kamomae, PhD, Department of Radiology, Nagoya University Graduate School of Medicine, Nagoya, Aichi, Japan)

Chapter 15. 5D Dosimetry in Radiotherapy Planning and Delivery
(Chengyu Shi, PhD, and Bingqi Guo, PhD, Department of Medical Physics, Memorial Sloan Kettering Cancer Center, New York, NY, US, and others)

Chapter 16. Machine Learning Applications in Medical Dosimetry
(Nataliya Kovalchuk, PhD and Lei Xing, PhD, Department of Radiation Oncology, Stanford University School of Medicine, Stanford, CA, US)



Medical Physics JournalReviewed by Colin G. Orton, Ph.D., Professor Emeritus, Wayne State University, Detroit

Keywords: radiotherapy, dosimetry, radiation detectors, radiation oncology, protons, IMRT, EPID, high-intensity ultrasound, photodynamic therapy, calorimetry, radiochromic film, 3D printing, machine learning, QA.

This book was written for Medical physicists, radiation physicists, radiation oncologists, radiation oncology, radiation therapy, medical physics, all medical schools and cancer centers/clinics, as well as medical dosimetrists programs, radiation therapists programs, and libraries of all universities.

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