Pulmonary Arterial Hypertension and Nifedipine: Pathogenesis and Management

$130.00

Victoria Estrada (Editor)

Series: New Developments in Medical Research
BISAC: MED010000

Pulmonary arterial hypertension (PAH) is a progressive, fatal syndrome characterized by increased vascular resistance that leads to right-ventricular hypertrophy and heart failure, eventually leading to death. The chapters of this book describe the molecular mechanisms and cellular events regulating vascular remodeling in PAH; the various animal models and drugs currently being used in various laboratories to study mechanisms leading to pulmonary arterial hypertension; and nifedipine, its pharmacology and it’s role in the management of pulmonary hypertension and some of the drawbacks concerning its use. The authors also discuss drug delivery systems that can lead to different crystallization forms of the immobilized drug which can lead to better solubility and bioavailability. (Imprint: Nova Biomedical)

Table of Contents

Table of Contents

Preface

Mechanisms of Vascular Remodeling in Pulmonary Arterial Hypertension
(Harika Sabbineni and Payaningal R. Somanath, Clinical and Experimental Therapeutics, College of Pharmacy, University of Georgia and Charlie Norwood VA Medical Center, Augusta, GA, USA, and other)

Methods to Study Cellular Plasticity in vitro and Pulmonary Vascular Remodeling in vivo in Pulmonary Arterial Hypertension
(Harika Sabbineni and Payaningal R. Somanath, Clinical and Experimental Therapeutics, College of Pharmacy, University of Georgia and Charlie Norwood VA Medical Center, Augusta, GA, USA, and other)

Pharmacological uses of Nifedipine
(Sampath Kumar Ethiraj, Joe V M Devasahayam, Gowrishankar Erode Singaravelu, Tony Oliver, Valentina S Joseph, Mandasmitha Sowmarpet, Aparna N Kurup, Unnikrishnan Pillai, Consultant in Hospital Medicine
Parkview Hospital, Fort Wayne, IN, USA, and others)

Nifedipine in Management of Pulmonary Hypertension
(Raj Parikh, Department of Internal Medicine, Rush University Medical Center, Chicago, IL, USA)

Nifedipine Controlled Release Systems Based on Inorganic Materials: A Review from the Start of the New Millenium to Present Date
(Inês J. Marques, Pedro D. Vaz, Carla D. Nunes, CQB, Departamento de Química e Bioquímica, Faculdade de Ciências da Universidade de Lisboa, Portugal, and other)

Index

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