Prostate cancer incidence and survival by race: A narrative review

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Authors: Krishna Thakore, Anthony La, Deepak Kumar Palanichami, Osazee Eguagie, Victor Adedara, Abidemi Fasanmi, Marios Loukas, and Emmanuel O Keku
Page Range: 69-75
Published in: International Public Health Journal, 15#1 (2023)
ISSN: 1947-4989

Table of Contents

ABSTRACT

Prostate cancer is the most common form of newly diagnosed cancer in men in the United States. Understanding the trends in prostate cancer incidence and survival among various racial groups can potentially help us guide prevention strategies and screening guidelines for at-risk populations. Demographic and clinical data on prostate cancer patients’ incidence and survival was obtained from SEER public-use data set. Prostate cancer survival rates were acquired by computing relative survival for the SEER-identified prostate cancer patients. Additionally, a literature search was performed using PubMed and Google Scholar to explore non-modifiable risk factors and other lifestyle factors affecting the incidence and survival of prostate cancer. Prostate cancer incidence has drastically increased since the introduction of PSA in 1988 and subsequently, approved by USFDA in 1994. The 5-year mortality for prostate cancer was higher in African American men than in Caucasians. High-fat diet, smoking, and obesity showed association with increased risk of prostate cancer incidence and worse prognosis. Prostate cancer affects African American men more than Caucasian men with a lower relevant survival rate. African American men between the age of 55 to 69 could benefit from routine PSA screening.

Keywords: Prostate cancer, incidence, survival, trends, mortality, race, African American, racial disparity, lifestyle factors, obesity, smoking

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