Propranolol: Medical Uses, Mechanisms of Action and Potential Adverse Effects

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Mislav Puljević, MD, PhD (Editor)
University of Zagreb, School of Medicine, University Hospital Center Zagreb, Clinic for Cardiovascular Diseases, Zagreb, Croatia

Series: Pharmacology – Research, Safety Testing and Regulation
BISAC: MED071000

Why would anyone want to write about propranolol, the first clinically utilized beta blocker? It is, after all, an outdated medicine. However, that is precisely why it is important to write about this treatment. Propranolol has been used in medical practices since 1962 and still plays an important role as a remedy for various diseases. Although primarily used in cardiovascular cases, it is also used in neurology, endocrinology, psychiatry and gastroenterology. Unfortunately, newly discovered beta blockers have replaced the use of propranolol as a regular treatment for cardiologists. Despite this, we strongly believe in conducting new studies that may show properties in propranolol being more beneficial to patients in some cases than new beta blockers.

There are situations now and then where all other forms of modern medicine have proven futile in aiding physicians with their practices. Many of these cases report new and interesting indications that show propranolol might work more efficiently under particular conditions. This book provides readers with the benefits of propranolol in different branches of the medical field. The authors of these chapters are elected, distinguished experts of different medical disciplines from all around the world. It was a great pleasure to gather their influential and respectable viewpoints about this neglected medicine. Additionally, the future of propranolol in terms of chemical theory is deliberated within these pages. The authors’ main objective was to shed light on the universality of propranolol. They hope to help save the use of this pharmaceutical before it is completely superseded by ever-evolving drugs.
(Imprint: Nova Biomedical)

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Table of Contents

Preface

Chapter One
Propranolol Pharmacology
(Eugen Javor and Marko Skelin, University Hospital Centre Sisters of Mercy, Zagreb, Croatia, and others)

Chapter Two
Propranolol Adverse Reactions
(Marko Skelin, Eugen Javor, General Hospital Sibenik, Medicinal Products’ Safety Committee, External expert, Croatia, and others)

Chapter Three
Propranolol use in Cardiac Arrhythmias
(Mislav Puljevic, M.D., Ph.D., University of Zagreb, School of Medicine, University Hospital Center Zagreb, Clinic for Cardiovascular Diseases, Zagreb, Croatia)

Chapter Four
Propranolol use in Heart Failure
(Jure Samardzic, University of Zagreb School of Medicine, University hospital Center Zagreb, Clinic for cardiovascular diseases, Zagreb, Croatia)

Chapter Five
Propranolol use in Hyperthyroidism
(Maja Baretic, Internal Clinic, Department of Endocrinology, University Hospital Centre Zagreb, Croatia)

Chapter Six
Propranolol use in Patients with Liver Cirrhosis
(Irena Hrstic and Rajko Ostojic, Pula General Hospital, School of Medicine, University of Zagreb, Zagreb, Croatia, and others)

Chapter Seven
Propranolol use in Psychiatry
(Martina Bojanic and Vesna Baric University Psychiatric Hospital Vrapèe, Zagreb, Croatia)

Chapter Eight
Propranolol use in Neurology
(Marina Puljević, University Hospital Centre Zagreb, Department of Neurology, Croatia)

Chapter Nine
Propranolol: A Protective Mechanism for Bone Marrow Dysfunction Following Injury
(Alicia M. Mohr, Ines G. Alamo, University of Florida/Department of Surgery, Gainesville, FL, USA)

Chapter Ten
Propranolol as Chiral Agent
(R. Èižmáriková, J. Valentová and A. Némethy, Department of Chemical Theory of Drugs, Faculty of Pharmacy, Comenius University in Bratislava, Bratislava, Slovak Republic)

Index


Audience: Doctors (Internal Medicine –All Branches), Pharmaceuticals, Biochemists

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