Table of Contents
Table of Contents
Introduction
Part 1. Free Radical Biology
Non-enzymatic antioxidants
1. Glutathione;pp. 3-19
(Dale Dickinson and Karen E. Iles, Dept. of Environmental Health Sciences, School of Public Health, Birmingham, AL, USA and others)
2. Vitamin C;pp. 21-40
(Tom Chan,Boehringer Ingelheim Pharmaceuticals, Ridgefield, CT, USA)
3. Vitamin E;pp. 41-60
(John R. Burnett and Michael Clarke,Royal Perth Hospital, Australia and others)
4. Nutritional antioxidants;pp. 61-77
(Tom S. Chan and Peter J. O’Brien, Boehringer Ingelheim Pharmaceuticals, Ridgefield, CT, USA and others)
Antioxidant enzymes
5. Superoxide dismutases;pp. 81-99
(Diane E. Cabelli, Dept. of Chemistry, Brookhaven National Laboratory, Upton, NY, USA USA)
6. SOD mimics;pp. 101-128
(Ivan Spasojevic and Ines Batinic-Haberle,Dept of Medicine, Duke University Medical Center, Durham, NC,USA)
7. Catalases;pp. 129-145
(Christian Obinger, Paul G. Furtmuller and Marcel Zmocky,Dept. of Chemistry, University of Natural Resources and Life Sciences, Vienna, Austria and others)
8. Glutathione peroxidases;pp. 147-169
(Regina Brigelius-Flohé and Leopold Flohé, Dept.Biochemistry of Micronutrients, German Institute of Human Nutrition Potsdam-Rehbrucke, Nuthetal, Germany and others)
9. Thioredoxins and glutaredoxins;pp. 171-186
(Yves Meyer, Arne Holmgren, Universite de Perpignan, France and others)
10. Peroxiredoxins;pp. 187-201
(Sue Goo Rhee and Hyun Ae Woo, Ewha Womans University, Seoul,Korea)
11. Role and regulation of heme oxygenase in oxidative stress;pp. 203-227
(Phyllis Dennery,University of Pennsylvania School of Medicine, Philadelphia,USA)
Redox signaling
12. NF-kB transcription factor: Mechanism of redox regulation;pp. 231-250
Nathalie Grandvaux, Dept. of Biochemistry, Universite de Montreal, Qc, CanadaCanada)
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13. The Nrf2 (NFE2L2) transcription factor pathway;pp. 251-273
(Volker Blank, Dept. of Medicine and Physiology, McGill University, Quebec,Canada)
14. Redox-modulated AP-1 signaling;pp. 275-292
(Katerina K. Papachroni and Athanassios Papavassiliou, Medical School, University of Athens,Greece)
Subcellular Compartmentalization
15. Oxidative stress in mitochondria;pp. 295-314
(Valeria Valez, Adrian Aicardo, Adriana Cassina, Celia Quijano and Rafael Radi,Departmento de Bioquimica, Universidad de la Republica, Montevideo,Uruguay and others)
16. Oxidative stress and lysosomes;pp. 315-332
(Tino Kurz, Ulf T. Brunk and Alexei Terman,Division of Pharmacology, Linkoping University,Sweden and others)
17. Oxidative stress and peroxisomes;pp. 333-358
(Nina A. Bonekamp, Michael Schrader and H. Dariush Fahimi, University of Aveiro, Portugal and others)
18. Oxidative stress and the endoplasmic reticulum;pp. 359-378
(Elizabeth D. Crane, Ali A. Al-Hashimi and Rick Austin, Dept. of Medicine, McMaster University and St. Joseph’s Hospital, Hamilton, Ontario, Canada)
Metabolism and Physiology
19. Systemic and Cellular Iron Homeostasis;pp. 381-421
(Kostas Pantopoulos, Sir Mortimer B. Davis Jewish General Hospital and others Montreal,Canada)
20. Copper metabolism;pp. 423-443
(Stephanie Cull and Jim Koropatnick, University of Western Ontario,Canada and others)
21. Inflammation;pp. 445-462
(Nurlan Dauletbaev and Larry C. Lands,Research Institute of McGill University Health Centre, Canada and others)
22. Mitochondrial ROS and oxygen sensing;pp. 463-477
(Robert B. Hamanaka and Navdeep S. Chandel, Northwestern University Medical School, Chicago, IL,USA)
23. Oxygen radicals and glutathione in aging;pp. 479-500
(Wulf Dröge, Immunotec Inc., Vaudreuil-Dorion,Canada)
24. Oxidative stress, telomeres and cell senescence;pp. 501-511
(João F. Passsos and Thomas von Zglinicki, Henry Wellcome Laboratory for Biogerontology Research, Newcastle upon Tyne,UK and others)
25. Reactive Oxygen Species, Cell Death Signaling and Apoptosis;pp. 513-545
(Pragathi Pallepati and Diana A. Averill,Departement des sciences biologiques, Universite du Quebec a Montreal,Canada)
26. Glutathione and apoptosis;pp. 547-573
(Magdalena L. Circu and Tak Yee Aw,Dept. of Molecular and Cellular Physiology, Louisiana State University Health Sciences Center, Shreveport, USA)
27. Circadian redox regulation;pp. 575-627
(C. David Rollo,Dept. of Biology, McMaster University, Hamilton, Ontario, Canada)
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Index