Preterm Delivery: Prevalence, Risk Factors and Related Complications

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Llanos Belmonte Andujar, PhD – Obstetrics and Gynaecology Department, University and Hospital Complex of Albacete, Spain
Ana Fuentes Rozalen, MD – Gynaecologist and Reproductive Medicine Specialist, Instituto Bernabéu, Alicante, Spain

Series: Neonatology Research Developments; Obstetrics and Gynecology Advances
BISAC: MED070000; MED033000; HEA041000
DOI: https://doi.org/10.52305/NJKO4527

If there is a complication of paramount importance in the field of maternofoetal health, it is preterm delivery. Defined as the birth of an infant before completing 37 weeks of gestation, preterm delivery stands as a primary contributor to foetal morbidity and mortality and places a major socio-economic burden on health systems. It is therefore undeniable, that preterm birth remains a substantial global health concern and a priority that needs to be addressed from different perspectives.

The primary aim of this book is to contribute to a deeper understanding of preterm delivery among healthcare professionals. For this purpose, this compilation gathers the collective knowledge of experts, researchers, and clinicians from diverse disciplines. Their contributions explore various aspects of preterm delivery, examining its causes, risk factors, clinical management, and long-term complications. In this way, the multifactorial nature of preterm delivery is unraveled in the diverse themes explored in this book.

Table of Contents

Preface

Chapter 1. Epidemiology of Preterm Birth
M. Pérez Haro¹, MD, L. Belmonte Andújar², PhD, A. Fuentes Rozalén¹, MD, and M.T. Gómez García², PhD
¹Bernabeu Institute, Albacete, Spain
²Obstetrics and Gynaecology Department, University and Hospital Complex of Albacete, Spain

Chapter 2.
Risk Factors for Preterm Delivery
M. L. Juan Rodrigo¹, MD, L. Sales Pérez¹, MD, A. Tello Delsors¹, MD, E. Achiaga Sánchez², MD, L. Belmonte Andujar¹, PhD, and M. T. Gómez García¹,³, PhD
¹Obstetrics and Gynaecology Department, University and Hospital of Albacete, Spain
²Create Fertility, London, United Kingdom
³Medical Science Department, School of Medicine of Albacete, Universidad de Castilla-La Mancha, Spain

Chapter 3. The Vaginal Microbiome and the Risk of Preterm Delivery
A. Fuentes Rozalén¹, MD, M. Pérez Haro¹,², MD, and Ll. Belmonte Andújar², PhD
¹Department of Reproductive Medicine, Bernabeu Institute, Alicante, Spain
²Department of Obstetrics and Gynaecology, Hospital General Almansa Albacete, Spain

Chapter 4. Screening for Preterm Birth
A. Tello Delsors¹, MD, M. L. Juan Rodrigo¹, MD, L. Sales Pérez¹, MD, L. Belmonte Andújar¹, PhD, E. Achiaga Sánchez², MD, and M. T. Gómez García¹,³, PhD
¹Obstetrics and Gynecology Department, University and Hospital of Albacete, Spain
²Create Fertility, London, United Kingdom
³Medical Science Department, School of Medicine of Albacete, Castilla-La Mancha University, Spain

Chapter 5. Prevention Methods Regarding Preterm Delivery
L. Sales Pérez¹, MD, A. Tello Delsors¹, MD, M. L. Juan Rodrigo¹, MD, Ll. Belmonte Andujar¹, PhD, E. Achiaga Sánchez², MD, and M. T. Gómez García³, PhD
¹Obstetrics and Gynecology Department, University and Hospital of Albacete, Spain
²Create Fertility, London, United Kingdom
³Medical Science Department, School of Medicine of Albacete, Castilla-La Mancha University, Spain

Chapter 6. Role of Antibiotic Therapy in Preterm Birth Care
I. Soler-Ferrero¹, MD, E. López del Cerro¹, MD, E. Cucarella Osca², MD, and M. González-Timoneda³, MD
¹Gynaecology and Obstetrics Department, Hospital Lluís Alcanyís, Xàtiva, Valencia, Spain
²Gynaecology and Obstetrics Department, Hospital of Alzira, Alzira, Valencia, Spain
³Gynaecology and Obstetrics Department, Hospital of Sagunt, Sagunt, Valencia, Spain

Chapter 7. Administration of Corticosteroids to Induce Maturation of Foetal Lung
M. González-Timoneda¹, MD, E. López del Cerro², MD, I. Soler-Ferrero², MD, E. Cucarella Osca³, MD, and A. González-Timoneda⁴, PhD
¹Gynaecology and Obstetrics Department, Hospital of Sagunt, Sagunt, Valencia, Spain
²Gynaecology and Obstetrics Department, Hospital Lluís Alcanyís, Xátiva, Valencia, Spain
³Gynaecology and Obstetrics Department, Hospital of Alzira, Alzira, Valencia, Spain
⁴Department of Nursing, University of Valencia, Spain

Chapter 8. Foetal Neuroprotection with Magnesium Sulphate
E. Cucarella Osca¹, MD, E. López del Cerro², MD, M. González-Timoneda³, MD, and I. Soler-Ferrero², MD
¹Gynaecology and Obstetrics Department, Hospital of Alzira, Alzira, Valencia, Spain
²Gynecology and Obstetrics Department, Hospital Lluis Alcanyís, Xàtiva, Valencia, Spain
³Gynaecology and Obstetrics Department, Hospital of Sagunt, Sagunt, Valencia, Spain

Chapter 9.
Immediate Preterm Perinatal Care: Complications and Limitations of Neonatal Cardiopulmonary Resuscitation
N. González Fajardo, MD, P. Tercero Baidez, MD, N. Roda Martínez, MD, A. Correas Sánchez, MD, and N. Patiño Navarro, PhD
Neonatology Department of Pediatrics Service, University Hospital of Albacete, Spain

Chapter 10. Respiratory Complications of Preterm Birth
P. Tercero Baidez, MD, N. González Fajardo, MD, N. Roda Martínez, MD, M. Vicent Rozas, MD, M. Ll. González Amo, MD, and M. Baquero Cano, PhD
Neonatology Department of Pediatrics Service, University Hospital of Albacete, Spain

Chapter 11.
Neonatal Necrotising Enterocolitis: Gastrointestinal Complications Related to Prematurity
M. Ll. González Amo¹, MD, N. Roda Martínez¹, MD, P. Tercero Baidez¹, MD, S. Rico Cardenal², MD, A. Castillo Serrano¹, MD, and E. Achiaga Sánchez³, MD
¹Neonatology Department of Paediatrics Service, University Hospital of Albacete, Spain
²Obstetrics and Gynaecology Department, Hospital of Villarrobledo, Albacete, Spain
³Create Fertility London, London, United Kingdom

Chapter 12. Retinopathy of Prematurity: Other Complications Related to Preterm Infants
M. Ll. González Amo¹, MD, M. Vicent Rozas¹, MD, N. Roda Martínez¹, MD, N. González Fajardo¹, MD, A. Castillo Serrano¹, MD, and E. Achiaga Sánchez², MD
¹Neonatology Department of Pediatrics Service, University Hospital of Albacete, Spain
²Create Fertility, London, United Kingdom

Chapter 13.
Early and Late Onset Neonatal Sepsis: Other Complications Associated with Prematurity
M. Ll. González Amo¹, MD, M. Vicent Rozas¹, MD, N. González Fajardo¹, MD, E. Gil Pons¹, MD, A. Castillo Serrano¹, MD, and E. González Amo²
¹Neonatology Department of Paediatrics Service, University Hospital of Albacete, Spain
²Complutense University, Faculty of Psychology and Speech Therapy, Spain

Chapter 14. Hemodynamic Complications of Prematurity
M. Vicent Rozas¹, MD, P. Tercero Baidez¹, MD, M. Ll. González Amo¹, MD, M. Bengoa Caamaño¹, MD, L. M. Escribano Gómez¹, MD, and J. M. García Cebrián², MD
¹Neonatology Department of Pediatrics Service, University Hospital of Albacete, Spain
²Obstetrics and Gynecology Department, Viamed Fertility Institute of Sevilla, Spain

Chapter 15. Complications and Neurological Sequelae in Preterm Newborn
N. Roda Martínez, MD, N. González Fajardo, MD, M. Vicent Rozas, MD, P. Tercero Baidez, MD, A. B. Delgado García, MD, and C. Pellicer Viudes MD
Neonatology Department of Pediatrics Service, University Hospital of Albacete, Spain

Index

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