Prescription Drugs: Global Perspectives, Long-Term Effects and Abuse Prevention


Alfredo Holt (Editor)
Maureen Vaughn (Editor)

Series: Pharmacology – Research, Safety Testing and Regulation
BISAC: MED071000

By the nature of its use, the intrathecal baclofen pump is frequently implanted in children and adults with either an advanced spinal, pelvic or hip deformity who suffer from muscle spasticity. These deformities often lead to additional surgical procedures either simultaneously or after the implantation of the baclofen pump and intrathecal catheterization. In the first chapter, several different scenarios are described and surgical maneuvers for mitigating complications and improving outcomes in patient populations are examined. The second chapter addresses all issues dealing with the prescription of baclofen, including the questions of doses and ways to deal with adverse effects. The conclusion is that baclofen is currently revolutionizing the therapeutic approach to AUD, with a prescription mainly based on the therapeutic alliance, where the patient gets personally involved, with the support of the physician, in the monitoring of the treatment.

According to the National Institute on Drug Abuse (NIDA), prescription drugs such as stimulants, opioids, and depressants are the most commonly misused classes of prescription drugs (NIDA, 2016). The authors of the third chapter examine NMUPD (i.e., depressants, opioids, and stimulants) among college students based on gender, living arrangements, and involvement in extracurricular activities. Specifically, if living arrangements and extracurricular activities influence the use of depressants, opioids, and stimulants while in college. The fourth chapter examines the relationship between nonmedical prescription drug (NMPD) use, perceived risk, ease of access, and peer disapproval of NMPDs based on school sports participation among 7th-12th grade male and female students. The final chapter of this book reviews the clinical evidence of the antimanic and the long-term mood stabilizing effect of memantine and suggests the possible biological effects. (Imprint: Nova)

Table of Contents

Table of Contents


Chapter 1. Intrathecal Baclofen Pumps in Spinal Deformity and Orthopedic Surgery
Jonathan Weyhenmeyer, and Albert Lee (Department of Neurosurgery, Indiana University School of Medicine, Goodman Campbell Brain and Spine, Indianapolis, IN, USA)

Chapter 2. Baclofen in the Treatment of Alcohol-Dependence: Indications, Contraindications and Adverse Effects
Renaud de Beaurepaire (Groupe Hospitalier Paul-Guiraud, Villejuif, France)

Chapter 3. Nonmedical Use of Depressants, Opioids, and Stimulants among College Students
Oladunni Oluwoye, Laura A. Nabors and Ashley L. Merianos,Rebecca A. Vidourek (Washington State University, USA and others)

Chapter 4. Sports Participation and Nonmedical Prescription Drug Use among Male and Female Students
Keith A. King, Rebecca A. Vidourek and Oladunni A. Oluwoye, Kelsi J. Wood and Ashley L. Merianos (University of Cincinnati, USA and others)

Chapter 5. The Antimanic and Sustained Mood Stabilizing Effect of Memantine
Guilia Serra, Francesca Serra, Francesca Demontis and Gino Serra (Child Neuropsychiatry Unit, Department of Neuroscience, I.R.C.C.S. Children Hospital Bambino Gesù, Rome, Italy)


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