Pituitary Adenoma: Pathophysiology, Diagnosis and Treatment Options

Kanakis Dimitrios N., MD, PhD (Editor)
Pathologist and Neuropathologist, Associate Professor of Pathology, University of Nicosia Medical School, Cyprus

Series: Endocrinology Research and Clinical Developments
BISAC: MED027000

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Pituitary adenomas are benign neoplasms that are associated with a variety of endocrinological disorders, which in turn cause substantial difficulties not only in the physical health of the affected individuals, but also in their psychosocial state.

Consequently, the imperative need for a prompt and accurate diagnosis of this tumor mobilizes investigators to concentrate and carry out their basic research in this particular area. Moreover, the wish to develop and try new therapeutic methods in daily practice brings together physicians from different medical disciplines; all of them cooperate harmonically to achieve the best for their patients.

It is the intention of Pituitary Adenoma: Pathophysiology, Diagnosis and Treatment Options to illustrate the current scientific results regarding the pathogenesis and progression of this neoplasm and also to explain in every detail the diverse diagnostic and therapeutic modalities used nowadays. In order to accomplish this aim, leading specialists were invited to participate with certain topics in the book, according to their field of expertise.

In brief, this completed work fulfills the initial expectations of the editor, the authors and the publisher, which are indeed glad to present this book to its wide intended audience. All of them are convinced that the content of its chapters will be a useful guide not only for medical professionals and students, but also for other neuroscientists exploring the secrets of pituitary adenoma’s pathogenesis. (Imprint: Nova Biomedical)

Foreword
George Kontogeorgos

Preface

Chapter 1. Introduction and Epidemiology
Doxakis Anestakis (Department of Histopathology, Laboratory of Forensic Medicine, School of Health Sciences, Medical Faculty, Aristotle University of Thessaloniki, Thessaloniki, Greece)

Chapter 2. Pituitary Morphogenesis and Development: From Physiology to Disease
John G. Yovos (Laboratory of Clinical and Molecular Endocrinology, 1st Department of Internal Medicine, School of Health Sciences, Medical Faculty, Aristotle University of Thessaloniki, Thessaloniki, Greece)

Chapter 3. The Role of Intracellular Signaling Pathways Notch, Hedgehog, and Wnt in the Pathogenesis of Pituitary Adenomas
Maria P. Yavropoulou (Laboratory of Clinical and Molecular Endocrinology, 1st Department of Internal Medicine, AHEPA Univ. Hospital, Thessaloniki, Greece)

Chapter 4. Clinical Symptomatology of Pituitary Adenomas: From a Neuropsychiatric Point of View
Magda Tsolaki (3rd Department of Neurology, School of Health Sciences, Medical Faculty, Aristotle University of Thessaloniki, Thessaloniki, Greece)

Chapter 5. Clinical Picture of Pituitary Adenomas: Endocrine Signs and Symptoms
Olga Karapanou and Stylianos Tsagarakis (Department Of Endocrinology, Diabetes and Metabolism, “Evaggelismos” Hospital, Athens, Greece)

Chapter 6. Gender Difference in Prolactinomas: A Comparative Clinicopathologic Study
Daizo Yoshida, Akira Teramoto Akio and Akio Morita (Department of Neurosurgery, Nippon Medical School, Tokyo, Japan)

Chapter 7. Pathology of Pituitary Adenomas
Wolfgang Saeger (Institute of Pathology and Neuropathology of the University of Hamburg, UKE, Hamburg, Germany)

Chapter 8. Imaging of Pituitary Adenomas
Antonios Drevelegas, Ellisabet Papadopoulou and Danai Chourmouzi (Interbalcan European Medical Center, Thessaloniki, Greece)

Chapter 9. Radionuclide Imaging and Therapy of Pituitary Adenomas
Efstratios Moralidis (Nuclear Medicine Department, School of Health Sciences, Medical Faculty, Aristotle University of Thessaloniki, Thessaloniki, Greece)

Chapter 10. Treatment of Pituitary Adenomas: An Integrated Approach
Olga Karapanou and Stylianos Tsagarakis (Department Of Endocrinology, Diabetes and Metabolism, “Evaggelismos” Hospital, Athens, Greece)

Chapter 11. Current Update of Surgical Management for Pituitary Adenomas
Se-Youn Jang and Choong-Hyun Kim (Department of Neurosurgery, Seoul Medical Center, Seoul, Korea and Department of Neurosurgery, Guri Hospital, Hanyang University, Korea)

Chapter 12. Vascular Anatomy of the Sellar Region, and Complications during Endoscopic Endonasal Transsphenoidal Surgery for Pituitary Adenomas
Yasuhiko Hayashi (Department of Neurosurgery, Graduate School of Medical Science, Kanazawa University, Kanazawa, Japan)

Chapter 13. Transsphenoidal Surgery for Pituitary Adenomas Guided by Intraoperative Magnetic Resonance Imaging (iMRI)
Sven Berkmann and Javier Fandino (Department of Neurosurgery, Kantonsspital Aarau, Aarau, Switzerland)

About the Editor

Index

Audience: Medical Students, General Practitioners, Endocrinologists, Radiologists, Neurologists, Psychiatrists, Neuropathologists, Neurosurgeons, Neuroscientists

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