Pineal Gland: Research Advances and Clinical Challenges


Angel Catalá, Ph.D. (Editor)
Facultad de Ciencias Exactas, Universidad Nacional de La Plata, CONICET, CIC., La Plata, Argentina

Series: Endocrinology Research and Clinical Developments
BISAC: MED027000

This book presents an overview of the research advances and clinical challenges of the pineal gland. The topics analyzed cover a broad spectrum of functions played by the pineal gland and present new information in this area of research. These topics include: the physiology and pathology of skeletal and cardiac muscles; the beneficial actions of melatonin; n3 and n6 essential fatty acids, lipoxygenation and melatonin synthesis; the structure and functions of the fish pineal organ; therapeutical aspects of melatonin in bone marrow and thyroid-associated immune regulation; melatonin as a promising cytoprotective agent against ischemia-reperfusion injury in the liver; therapeutic approaches with melatonin; melatonin and neuroinflammation: encouraging findings vs. fundamental problems; melatonin and aging; pineal parenchymal tumor of intermediate differentiation; pineal glial cysts: features and clinical significance; melatonin as a modulator of radiosensibility and chemosensibility in cancer, circadian rhythm and melatonin associated with cancer development and treatment. (Imprint: Nova Biomedical)



Table of Contents


Chapter 1. The Physiology and Pathology of Skeletal and Cardiac Muscle: Beneficial Actions of Melatonin
Ana Coto-Montes, Juan Antonio Boga, Dun X Tan and Russ Reiter (Department of Morphology and Cell Biology University of Oviedo, Oviedo, Spain, and others)

Chapter 2. Pineal Gland: N3 and N6 Essential Fatty Acids, Lipoxygenation and Melatonin Synthesis
Angel Catalá (Institute of Physical and Theoretical Investigations, Theoretical and Applied, (INIFTA-CCT La Plata-CONICET), Faculty of Exact Sciences, National University of La Plata, La Plata, Argentina)

Chapter 3. Structural Diversity and Functional Integrity of the Fish Pineal Gland
Saumen Kumar Maitra and Palash Kumar Pal (Department of Zoology, Visva-Bharati (A Central University), Santiniketan, India)

Chapter 4. Therapeutic Aspects of Melatonin in Bone Marrow and Thyroid Associated Immune Regulation
Shraddha Rastogi, Rakesh Verma and Chandana Haldar (Pineal Research Laboratory, Department of Zoology, Institute of Science, Banaras Hindu University, Varanasi, India)

Chapter 5. Melatonin: A Promising Cytoprotective Agent against Ischemia-Reperfusion Injury in the Liver
J.J. García, L. López-Pingarrón, E. Esteban-Zubero, G. Pola, P. Iñigo, J.M. Ramírez, C. Bernardos and F.A. García-Gil (University of Zaragoza, Zaragoza, Spain)

Chapter 6. Therapeutical Approaches with Melatonin
Darío Acuña-Castroviejo (Center for Biomedical Research, University of Granada, Granada, Spain)

Chapter 7. Melatonin and Neuroinflammation: Encouraging Findings vs. Fundamental Problems
Rüdiger Hardeland and Johann Friedrich Blumenbach (Institute of Zoology and Anthropology, University of Göttingen, Göttingen, Germany)

Chapter 8. Melatonin and Aging
Surbhi and Randy J Nelson (Department of Neuroscience, The Ohio State University Wexner Medical Center, Columbus, USA)

Chapter 9. Pineal Parenchymal Tumors of Intermediate Differentiation
Jordan M. Gales and Richard A. Prayson (Cleveland Clinic Lerner College of Medicine, Department of Anatomic Pathology, Cleveland, USA)

Chapter 10. Pineal Glial Cysts: Features and Clinical Significance
Kara L. Gawalek and Richard A. Prayson (Cleveland Clinic Lerner College of Medicine, Department of Anatomic Pathology, Cleveland, USA)

Chapter 11. Melatonin as Modulator of Radiosensibility and Chemosensibility in Cancer
Alonso-González C, González A, Cos S, González-González A, Menéndez-Menéndez J and Martínez-Campa C (Department of Physiology and Pharmacology School of Medicine, Cardenal Herrera Oria s/n University of Cantabria and Instituto de Investigacion Valdecilla (IDIVAL), Santander, Spain)

Chapter 12. Circadian Rhythm and Melatonin Associated with Cancer Development and Treatment
Rubens de Paula Junior and Debora Aparecida Pires de Campos Zuccari (Medical School of Sao Jose do Rio Preto, São José do Rio Preto, Sao Paulo, and others)


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