Photodynamic Therapy: Fundamentals, Applications and Health Outcomes

Adrian G. Hugo (Editor)

Series: Cancer Etiology, Diagnosis and Treatments
BISAC: MED062000

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$230.00

Volume 10

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Special issue: Resilience in breaking the cycle of children’s environmental health disparities
Edited by I Leslie Rubin, Robert J Geller, Abby Mutic, Benjamin A Gitterman, Nathan Mutic, Wayne Garfinkel, Claire D Coles, Kurt Martinuzzi, and Joav Merrick

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Photodynamic therapy (PDT) is a well-established clinical modality for cancer, cardiovascular, ophthalmic, dermatological, and dental diseases. PDT is based on the activation of photosensitizer agents with specific wavelength of light, which results in energy transfer cascades that ultimately yield cytotoxic reactive oxygen species that can render cell death. This book discusses the fundamentals, applications and health outcomes of photodynamic therapy.

(Imprint: Nova Biomedical)

Preface

Chapter 1 - Multifunctional Nanoparticles in Photodynamic Therapy: Recent Developments (pp. 1-32)
Juan L. Vivero-Escoto (Department of Chemistry, The Center for Biomedical Engineering and Science, University of North Carolina at Charlotte, Charlotte, NC, USA)

Chapter 2 - Recent Advances in Nanomedicine for Photodynamic Therapy of Cancer (pp. 33-58)
Yamin Yang and Hongjun Wang (Department of Chemistry, Chemical Biology and Biomedical Engineering, Stevens Institute of Technology, Hoboken, NJ, USA)

Chapter 3 - The Mechanism of Action of Topical Dermatological Photodynamic Therapy (pp. 59-102)
Alison Curnow and Jessica Tyrrell (European Centre for Environment and Human Health, University of Exeter, UK)

Chapter 4 - Nanotechnology-Based Cancer PhotoDynamic Therapy (pp. 103-122)
Elisa Panzarini and Luciana Dini (Department of Biological and Environmental Science and Technology (Di.S.Te.B.A.), University of Salento, Lecce, Italy)

Chapter 5 - Photodynamic Therapy in Animal Health (pp. 123-152)
Michelle Peneluppi Silva and Antonio Olavo Cardoso Jorge (Department of Biosciences and Oral Diagnosis, Institute of Science and Technology, UNESP – Univ Estadual Paulista, São José dos Campos, São Paulo, Brazil)

Chapter 6 - The Use of Photosensitizers in Photodynamic Therapy (pp. 153-172)
Michelle Peneluppi Silva and Antonio Olavo Cardoso Jorge (Department of Biosciences and Oral Diagnosis, Institute of Science and Technology, UNESP – Univ Estadual Paulista, São José dos Campos, São Paulo, Brazil)

Chapter 7 - In Vitro and In Vivo 5-Aminolevulinic Acid-Based Photodynamic Therapy in Sensitive and Drug Resistant Leukemic Murine Cells (pp. 173-192)
Berenice Diez, Silvia Hajos, Roberto Meiss, Glenda Ernst, Maria Julieta Teijo, Alcira Batlle and Haydée Fukuda (Departamento de Química Biológica, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, Argentina, and others)

Chapter 8 - 4-Thiothymidine and Its Analogues as UVA-Activated Photosensitizers (pp. 193-206)
Giuseppe Trigiante and Yao-Zhong Xu (LHCS Department, The Open University, Milton Keynes, and others)

Chapter 9 - Towards Multifunctional Hybrid Nanosystems for PDT: Polymeric Nanostructures Containing Zinc Selenide Nanoparticles and Photosensitizer (pp. 207-224)
T. E. Sukhanova, M. L. Gelfond, V. A. Bershtein, S. V. Valueva, M. E. Vylegzhanina, A. Ya. Volkov, A. A. Kutin and G. N. Matveeva (Institute of Macromolecular Compounds, Russian Academy of Sciences, St.-Petersburg, Russia, and others)

Chapter 10 - Ocular Photodynamic Therapy (pp. 225-240)
Assaf Dotan and Rita Ehrlich (Department of Ophthalmology, Rabin Medical Center, PetachTikva, Israel)

Index

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