Pathogenic Bacteria: Pathogenesis, Virulence Factors and Antibacterial Treatment Strategies


Keith D. Watts (Editor)

Series: Microbiology Research Advances
BISAC: MED052000

Although most forms of bacteria are harmless, pathogenic bacteria can cause disease and as such these microorganisms warrant scientific attention. Chapter One describes the virulence problem caused by extracellular polymeric substances and antibacterial compounds capable of inhibiting their production, biofilm formation, and bacterial pathogenicity. Chapter Two provides an overview of biophysical techniques that can validate targets of phytochemicals with anti-virulence properties that can help elucidate their mode of action. Chapter Three discusses terpenes’ anti-virulence modes of action, inhibition of biofilm, disruption of the cell wall and bacterial membrane, intercellular leakage, interruption of nucleic acids transcription, and interference with the quorum sensing signaling process. Chapter Four investigates the anti-pathogenic potential of essential oil from the plant asafoetida obtained through microwave-assisted extraction method. Finally, Chapter Five deals with the effect of audible sound waves on bacteria.

Table of Contents


Chapter 1. Inhibition of Extracellular Polymeric Substances to Reduce Bacteria Pathogenicity
(L. A. Ortega-Ramirez, M. M. Gutiérrez-Pacheco, J. C. López-Romero and J. F. Ayala-Zavala – Departamento de Ciencias de la Salud, Universidad Estatal de Sonora. San Luis Río Colorado, Sonora, México, et al.)

Chapter 2. Biophysical Tools to Explore the Anti-Virulence Mode of Action of Phytochemicals Against Pathogenic Bacteria
(F. J. Vázquez-Armenta, A. A. López-Zavala, A. T. Bernal-Mercado, M. R. Tapia-Rodríguez, D. Encinas-Basurto4 and J. F. Ayala-Zavala – Departamento de Ciencias Químico Biológicas, Universidad de Sonora, Hermosillo, Sonora, México, et al.)

Chapter 3. Antivirulence Mechanisms of Plant Terpenes Against Pathogenic Bacteria
(Melvin R. Tapia-Rodriguez, F. Javier Vazquez-Armenta, Cristobal J. Gonzalez-Perez, Yessica Enciso-Martinez, Maria Gonzalez-Leyva and J. Fernando Ayala-Zavala – Departamento de Biotecnología y Ciencias Alimentarias, Instituto Tecnologico de Sonora, Ciudad Obregon, Sonora, Mexico, et al.)

Chapter 4. Antipathogenic Potential of Ferula asafoetida Essential Oil
(Sanjay Joshi, Pinakin Khambhala, Mayank Shah, Shailja Varma, Gemini Gajera, Sriram Seshadri and Vijay Kothari – National Foods, Vadodara, India, et al.)

Chapter 5. Sonic Stimulation at Certain Frequencies can Confer Limited Protection on Nematode Host Infected with Serratia marcescens
(Gemini Gajera, Purvi Garsondiya, Anjali Kalla, Himani Zaveri, Pinal Sanandiya, Drashti Patel, Nidhi Patel, Megha Maheshwari and Vijay Kothari – Institute of Science, Nirma University, Ahmedabad, India)


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