Paraneoplastic Syndromes: Symptoms, Diagnosis and Treatment


Lora H. Winter (Editor)

Series: Cancer Etiology, Diagnosis and Treatments
BISAC: MED062000

Paraneoplastic Syndromes (PNS) are a group of disorders that cause endocrinologic, hematologic, neurologic, and dermatologic manifestations of cancer. These conditions are not directly caused by tumor metastasis, but rather the malignancies produce hormones and other proteins which act to disrupt the body’s homeostasis, thereby causing symptoms. The neurological complications of PNS are the result of an immune response to tumor antigens. PNS have been associated with a variety of cancers, such as genitourinary, ovarian, and breast, but are most commonly associated with neuroendocrine tumors.

These syndromes can even occur before the primary tumor is identified. Historically, these conditions were considered rare, but given the difficulties with diagnosis, the exact prevalence is unknown. This book focuses on the symptoms, diagnosis, and treatment of PNS. More specifically, it discusses current concepts in common PNS; cutaneous PNS and skin features of internal malignancy; PNS in patients with malignancies of the genitourinary tract; PNS polyneuropathies; the correction of cancer-related anemai with oxyresveratrol; and PNS associated with lung cancer. (Imprint: Nova Biomedical )

Table of Contents

Table of Contents


Chapter 1 – Current Concepts in Common Paraneoplastic Syndromes: Symptoms, Diagnosis and Treatment (pp. 1-22)
Candace Mainor, Ashiq Masood, Muddassir Shahdhar and Heather D. Mannuel (Assistant Professor of Medicine, Program Director, Oncology/ Hematology program, University of Maryland Greenebaum Cancer Center, Baltimore, MD, and others)

Chapter 2 – Cutaneous Paraneoplastic Syndromes and Skin Features of Internal Malignancy: Symptoms, Diagnosis and Treatment (pp. 23-106)
M. Yuste Chaves and M. González de Arriba (Servicio de Dermatología Hospital Clínico Universitario de Salamanca, Spain)

Chapter 3 – Paraneoplastic Syndromes in Patients with Malignancies of the Genitourinary Tract (pp. 107-148)
Emilio Sacco, Ph.D. and Riccardo Bientinesi, M.D. (Urology Department, “Agostino Gemelli” Academic Hospital, Catholic University Medical School, Rome, Italy)

Chapter 4 – Paraneoplastic Polyneuropathies: Searching in the Mist (pp. 149-162)
Antonios Kerasnoudis, M.D. (Neurological Private Practice, Ethnikis Antistasis, Serres, Greece, and others)

Chapter 5 – Correction of Cancer-Related Anemia with Oxyresveratrol (pp. 163-200)
G. I. Solyanik, O. N. Pyaskovskaya and N. K. Rodionova (Institute of Experimental Pathology, Oncology and Radiobiology of National Academy of Sciences of Ukraine, Ukraine)

Chapter 6 – Paraneoplastic Syndromes Associated with Lung Cancer (pp. 201-224)
Neven Z. Rakusic and Nevena Rakusic (Clinical Hospital Centre Zagreb, University Hospital for Lung Diseases “Jordanovac”, Zagreb, Croatia, and others)


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